ID   Y2987_NOSS1             Reviewed;         307 AA.
AC   Q8YSU5;
DT   21-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2002, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=UPF0187 protein alr2987;
GN   OrderedLocusNames=alr2987;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0187 family. {ECO:0000305}.
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DR   EMBL; BA000019; BAB74686.1; -; Genomic_DNA.
DR   PIR; AD2179; AD2179.
DR   RefSeq; WP_010997138.1; NZ_RSCN01000003.1.
DR   AlphaFoldDB; Q8YSU5; -.
DR   SMR; Q8YSU5; -.
DR   STRING; 103690.17132081; -.
DR   EnsemblBacteria; BAB74686; BAB74686; BAB74686.
DR   KEGG; ana:alr2987; -.
DR   eggNOG; COG3781; Bacteria.
DR   OMA; TDICGAC; -.
DR   OrthoDB; 1348684at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005254; F:chloride channel activity; IEA:InterPro.
DR   InterPro; IPR021134; Bestrophin/UPF0187.
DR   InterPro; IPR044669; UPF0187.
DR   PANTHER; PTHR33281; PTHR33281; 1.
DR   Pfam; PF01062; Bestrophin; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..307
FT                   /note="UPF0187 protein alr2987"
FT                   /id="PRO_0000217667"
FT   TRANSMEM        19..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        236..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   307 AA;  34686 MW;  8AF2061380343DF2 CRC64;
     MTVAKKHWFQ IAFQLRGSVI GAIYKRVICC ALFGVLVTLL YQLKIPVSQP ILGSVIPSIV
     LGLLLVFRTN TAYDRFWEGR KAWGSIVNNT RNLARQIWVS VEEVSLKDRE AKISVLNLLV
     AFAVATKLHL RGEPINSELE DLISTSRYFK LKSMNNPPLE VAFWIGDYLQ QQYTCKCLNS
     YQLTSIQELL NNLVDNLGSC ERILRTPMPL AYSIHLKQLL LLYCFLLPFQ MVESLGWWTG
     LVVGLVSFTL FGIEAIGLEI ENPFGYDPND LPLDAICNTM KRNIDDLTSL SPNVRSHDLG
     ETSNVTI