ID   Y2129_CUPNH             Reviewed;         289 AA.
AC   Q0K9U5;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=UPF0173 metal-dependent hydrolase H16_A2129 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=H16_A2129;
OS   Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS   / H16 / Stanier 337) (Ralstonia eutropha).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=381666;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337;
RX   PubMed=16964242; DOI=10.1038/nbt1244;
RA   Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA   Eitinger T., Ewering C., Poetter M., Schwartz E., Strittmatter A., Voss I.,
RA   Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT   "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT   eutropha H16.";
RL   Nat. Biotechnol. 24:1257-1262(2006).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM260479; CAJ93226.1; -; Genomic_DNA.
DR   RefSeq; WP_010810615.1; NZ_CP039287.1.
DR   AlphaFoldDB; Q0K9U5; -.
DR   SMR; Q0K9U5; -.
DR   STRING; 381666.H16_A2129; -.
DR   EnsemblBacteria; CAJ93226; CAJ93226; H16_A2129.
DR   GeneID; 57644256; -.
DR   KEGG; reh:H16_A2129; -.
DR   eggNOG; COG2220; Bacteria.
DR   HOGENOM; CLU_070010_4_0_4; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 767622at2; -.
DR   Proteomes; UP000008210; Chromosome 1.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..289
FT                   /note="UPF0173 metal-dependent hydrolase H16_A2129"
FT                   /id="PRO_0000367200"
SQ   SEQUENCE   289 AA;  30150 MW;  060580D954AFFBEA CRC64;
     MTRLRAVLLA TVIALLGACA APTPPAEARR PMPAGQPTAG KAEVLWLGQA ATRITTPGGK
     VIVVDPWLTT NPKTPPGFKQ LSALGKVDLI LVTHAHSDHL GDAPALARLT NAPIYNGGGL
     GQALVSLGMV PAAQAQRFGK SGTVMPFGPT GPRITAVHAE HSSELALKNP ATGKDETHYG
     GEPVGYIIEL ENGFKIWHMG DTGLFGDMRL IGEVYKPDLV LIPIGGHFTM GPQEAAIAVR
     DLIRPRFAIP IHYQTSPQLS GTPEAFKAAL GAGAAAGVIV PQPGEKVDF