ID   Y2124_STAHJ             Reviewed;         304 AA.
AC   Q4L4J2;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Nucleotide-binding protein SH2124 {ECO:0000255|HAMAP-Rule:MF_00636};
GN   OrderedLocusNames=SH2124;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- FUNCTION: Displays ATPase and GTPase activities. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
CC   -!- SIMILARITY: Belongs to the RapZ-like family. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
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DR   EMBL; AP006716; BAE05433.1; -; Genomic_DNA.
DR   RefSeq; WP_011276388.1; NC_007168.1.
DR   AlphaFoldDB; Q4L4J2; -.
DR   SMR; Q4L4J2; -.
DR   STRING; 279808.SH2124; -.
DR   EnsemblBacteria; BAE05433; BAE05433; SH2124.
DR   GeneID; 58061747; -.
DR   KEGG; sha:SH2124; -.
DR   eggNOG; COG1660; Bacteria.
DR   HOGENOM; CLU_059558_0_0_9; -.
DR   OMA; TVMSFGF; -.
DR   OrthoDB; 1603998at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00636; RapZ_like; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005337; RapZ-like.
DR   PANTHER; PTHR30448; PTHR30448; 1.
DR   Pfam; PF03668; ATP_bind_2; 1.
DR   PIRSF; PIRSF005052; P-loopkin; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; GTP-binding; Nucleotide-binding.
FT   CHAIN           1..304
FT                   /note="Nucleotide-binding protein SH2124"
FT                   /id="PRO_0000259005"
FT   BINDING         19..26
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
FT   BINDING         70..73
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
SQ   SEQUENCE   304 AA;  34845 MW;  A134C2D36BCB7043 CRC64;
     MTNHKENEMS KSELLVVTGL SGAGKSVVIQ CLEDIGYFCV DNLPPILLPK FVELMEQGNP
     SLQKVAIAID LRGKELFKSL VEEIDAIKSR NDVIVDVMFL EAETEKLISR YKESRRAHPL
     NENGQMSLMD SILEEKQLLS NIRTIANYIV DTTQLTTKEL KARVKEKFED ENFKSFSINV
     SSFGFKHGIQ KDADLVFDVR FLPNPYYVED LRPMTGEDEP VYHYVMKWKE TEIFFEKLMD
     LLKFMIPGYK KEGKSQLVIA IGCTGGQHRS VALAKRIGEE LTEIFDYNVY VHHRDAHIES
     GVRK