ID   Y2104_STRP1             Reviewed;         243 AA.
AC   Q99XQ1; Q48W69;
DT   16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=UPF0246 protein SPy_2104/M5005_Spy1788 {ECO:0000255|HAMAP-Rule:MF_00652};
GN   OrderedLocusNames=SPy_2104, M5005_Spy1788;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- SIMILARITY: Belongs to the UPF0246 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00652}.
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DR   EMBL; AE004092; AAK34751.1; -; Genomic_DNA.
DR   EMBL; CP000017; AAZ52406.1; -; Genomic_DNA.
DR   RefSeq; NP_270030.1; NC_002737.2.
DR   AlphaFoldDB; Q99XQ1; -.
DR   SMR; Q99XQ1; -.
DR   PaxDb; Q99XQ1; -.
DR   EnsemblBacteria; AAK34751; AAK34751; SPy_2104.
DR   KEGG; spy:SPy_2104; -.
DR   KEGG; spz:M5005_Spy1788; -.
DR   PATRIC; fig|160490.10.peg.1822; -.
DR   HOGENOM; CLU_061989_2_1_9; -.
DR   OMA; WKNGQYK; -.
DR   Proteomes; UP000000750; Chromosome.
DR   HAMAP; MF_00652; UPF0246; 1.
DR   InterPro; IPR005583; YaaA.
DR   PANTHER; PTHR30283; PTHR30283; 1.
DR   Pfam; PF03883; H2O2_YaaD; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..243
FT                   /note="UPF0246 protein SPy_2104/M5005_Spy1788"
FT                   /id="PRO_0000204011"
SQ   SEQUENCE   243 AA;  28271 MW;  02232AA3CE5B38DA CRC64;
     MLTFLIPTAK EMTIPKESHP HLLPQDSQAI LKIMAAMTTE DLAKSYRIKE ESAKKEQQRW
     QDMASQQSLA YPAYQLFNGL MYRHIKRDKL TTQEQAYLTQ QVYITSSFYG IIPANHPIAE
     HRHDFHTRIK IEGQSLKSYW RPCYNQFAKE HPQVISLLSS EFDDVFSKDC KQLWISPKFM
     AEKEGQFKTH STISKKARGA FLTACMENNC QTVDSLKSLV FAGFYYHPDL STDHEFVYIK
     KEA