ID   CAPSH_BPKVM             Reviewed;         514 AA.
AC   Q6WHE1;
DT   04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   02-DEC-2020, entry version 47.
DE   RecName: Full=Major capsid protein {ECO:0000250|UniProtKB:P04535, ECO:0000255|HAMAP-Rule:MF_04117};
DE   AltName: Full=Gene product 23 {ECO:0000250|UniProtKB:P04535};
DE   AltName: Full=Major head protein {ECO:0000255|HAMAP-Rule:MF_04117, ECO:0000305};
DE   AltName: Full=gp23 {ECO:0000250|UniProtKB:P04535, ECO:0000255|HAMAP-Rule:MF_04117};
DE   Contains:
DE     RecName: Full=Mature major capsid protein {ECO:0000250|UniProtKB:P04535, ECO:0000255|HAMAP-Rule:MF_04117};
DE     AltName: Full=gp23* {ECO:0000255|HAMAP-Rule:MF_04117, ECO:0000305};
GN   Name=23 {ECO:0000312|EMBL:AAQ64432.1};
GN   OrderedLocusNames=KVP40.0363 {ECO:0000312|EMBL:AAQ64432.1};
OS   Vibrio phage KVP40 (isolate Vibrio parahaemolyticus/Japan/Matsuzaki/1991)
OS   (KVP40) (Bacteriophage KVP40).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Schizotequatrovirus.
OX   NCBI_TaxID=1283340 {ECO:0000312|Proteomes:UP000001785};
OH   NCBI_TaxID=670; Vibrio parahaemolyticus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Isolate Vibrio parahaemolyticus/Japan/Matsuzaki /1991
RC   {ECO:0000312|Proteomes:UP000001785};
RX   PubMed=12923095; DOI=10.1128/jb.185.17.5220-5233.2003;
RA   Miller E.S., Heidelberg J.F., Eisen J.A., Nelson W.C., Durkin A.S.,
RA   Ciecko A., Feldblyum T.V., White O., Paulsen I.T., Nierman W.C., Lee J.,
RA   Szczypinski B., Fraser C.M.;
RT   "Complete genome sequence of the broad-host-range vibriophage KVP40:
RT   comparative genomics of a T4-related bacteriophage.";
RL   J. Bacteriol. 185:5220-5233(2003).
RN   [2]
RP   PROTEIN SEQUENCE OF 63-80, AND PROTEOLYTIC CLEAVAGE.
RX   PubMed=9514973; DOI=10.1006/viro.1997.9018;
RA   Matsuzaki S., Inoue T., Tanaka S.;
RT   "A vibriophage, KVP40, with major capsid protein homologous to gp23* of
RT   coliphage T4.";
RL   Virology 242:314-318(1998).
CC   -!- FUNCTION: Major capsid protein that self-associates to form hexamers,
CC       building most of the capsid in association with pentons made of the
CC       capsid vertex protein and one dodecamer of the portal protein.
CC       {ECO:0000255|HAMAP-Rule:MF_04117}.
CC   -!- SUBUNIT: Homohexamer. Interacts with the portal protein. Interacts with
CC       the capsid vertex protein that forms pentamers. {ECO:0000255|HAMAP-
CC       Rule:MF_04117}.
CC   -!- SUBCELLULAR LOCATION: [Major capsid protein]: Virion. Note=Part of the
CC       capsid icosahedric shell of the immature virion.
CC       {ECO:0000250|UniProtKB:P04535}.
CC   -!- SUBCELLULAR LOCATION: [Mature major capsid protein]: Virion
CC       {ECO:0000250|UniProtKB:P04535, ECO:0000255|HAMAP-Rule:MF_04117}.
CC       Note=Part of the icosahedric capsid shell of the mature virion.
CC       {ECO:0000255|HAMAP-Rule:MF_04117}.
CC   -!- PTM: A proteolytic cleavage gives rise to the mature major capsid
CC       protein during virus maturation. {ECO:0000255|HAMAP-Rule:MF_04117}.
CC   -!- SIMILARITY: Belongs to the T4 phage capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; AY283928; AAQ64432.1; -; Genomic_DNA.
DR   RefSeq; NP_899609.1; NC_005083.2.
DR   SMR; Q6WHE1; -.
DR   GeneID; 2546039; -.
DR   KEGG; vg:2546039; -.
DR   Proteomes; UP000001785; Genome.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04117; CAPSID_H_T4; 1.
DR   InterPro; IPR038997; CAPSID_Myoviridae.
DR   InterPro; IPR010762; Gp23/Gp24_T4-like.
DR   Pfam; PF07068; Gp23; 1.
PE   1: Evidence at protein level;
KW   Capsid protein; Direct protein sequencing; Late protein;
KW   Reference proteome; Virion.
FT   CHAIN           1..514
FT                   /note="Major capsid protein"
FT                   /id="PRO_0000432344"
FT   CHAIN           63..514
FT                   /note="Mature major capsid protein"
FT                   /evidence="ECO:0000269|PubMed:9514973"
FT                   /id="PRO_0000442456"
FT   SITE            62..63
FT                   /note="Cleavage"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_04117,
FT                   ECO:0000269|PubMed:9514973"
SQ   SEQUENCE   514 AA;  54700 MW;  BE1FDF2AA9C16C98 CRC64;
     MNLTEKWKDL LEAEGADMPE IATATKQKIM SKIFENQDRD INNDPMYRDP QLVEAFNAGL
     NEAVVNGDHG YDPANIAQGV TTGAVTNIGP TVMGMVRRAI PQLIAFDIAG VQPMTGPTSQ
     VFTLRSVYGK DPLTGAEAFH PTRQADASFS GQAAASTIAD FPTTGAATDG TPYKAEVTTS
     GGDVSMRYFL ALGAVTLAVA GQMTATEYTD GVAGGLLVEI DAGMATSQAE LQENFNGSSN
     NEWNEMSFRI DKQVVEAKSR QLKAQYSIEL AQDLRAVHGL DADAELSGIL ANEVMVELNR
     EIVNLVNSQA QIGKSGWTQG AGAAGVFDFS DAVDVKGARW AGEAYKALLI QIEKEANEIG
     RQTGRGNGNF IIASRNVVSA LSMTDTLVGP AAQGMQDGSM NTDTNQTVFA GVLGGRFKVY
     IDQYAVNDYF TVGFKGSTEM DAGVFYSPYV PLTPLRGSDS KNFQPVIGFK TRYGVQVNPF
     ADPTASATKV GNGAPVAASM GKNAYFRRVF VKGL