ID   VPB14_MYCTU             Reviewed;          71 AA.
AC   P95262; L0TB24;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 2.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Putative antitoxin VapB14;
GN   Name=vapB14; OrderedLocusNames=Rv1952;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   POSSIBLE FUNCTION.
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=15718296; DOI=10.1093/nar/gki201;
RA   Pandey D.P., Gerdes K.;
RT   "Toxin-antitoxin loci are highly abundant in free-living but lost from
RT   host-associated prokaryotes.";
RL   Nucleic Acids Res. 33:966-976(2005).
CC   -!- FUNCTION: Putative antitoxin component of a possible type II toxin-
CC       antitoxin (TA) system. The cognate toxin is VapB14.
CC       {ECO:0000305|PubMed:15718296}.
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DR   EMBL; AL123456; CCP44719.1; -; Genomic_DNA.
DR   PIR; D70638; D70638.
DR   RefSeq; NP_216468.1; NC_000962.3.
DR   RefSeq; WP_003409878.1; NZ_NVQJ01000048.1.
DR   AlphaFoldDB; P95262; -.
DR   SMR; P95262; -.
DR   STRING; 83332.Rv1952; -.
DR   PaxDb; P95262; -.
DR   DNASU; 885971; -.
DR   GeneID; 45425923; -.
DR   GeneID; 885971; -.
DR   KEGG; mtu:Rv1952; -.
DR   PATRIC; fig|83332.111.peg.2171; -.
DR   TubercuList; Rv1952; -.
DR   eggNOG; COG4691; Bacteria.
DR   OMA; TDAQVEF; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.1220.10; -; 1.
DR   InterPro; IPR013321; Arc_rbn_hlx_hlx.
DR   InterPro; IPR010985; Ribbon_hlx_hlx.
DR   SUPFAM; SSF47598; SSF47598; 1.
PE   4: Predicted;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..71
FT                   /note="Putative antitoxin VapB14"
FT                   /id="PRO_0000408061"
SQ   SEQUENCE   71 AA;  7700 MW;  54A2012362C28A5F CRC64;
     MIRNLPEGTK AALRVRAARH HHSVEAEARA ILTAGLLGEE VPMPVLLAAD SGHDIDFEPE
     RLGLIARTPQ L