ID   VPAP_HHV7J              Reviewed;         364 AA.
AC   P52440;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   02-JUN-2021, entry version 74.
DE   RecName: Full=DNA polymerase processivity factor;
DE   AltName: Full=Polymerase accessory protein;
DE            Short=PAP;
GN   Name=U27;
OS   Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=57278;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8709220; DOI=10.1128/jvi.70.9.5975-5989.1996;
RA   Nicholas J.;
RT   "Determination and analysis of the complete nucleotide sequence of human
RT   herpesvirus.";
RL   J. Virol. 70:5975-5989(1996).
CC   -!- FUNCTION: Accessory subunit of the DNA polymerase that acts to increase
CC       the processivity of polymerization. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae polymerase accessory protein
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U43400; AAC54689.1; -; Genomic_DNA.
DR   PIR; T41929; T41929.
DR   RefSeq; YP_073767.1; NC_001716.2.
DR   SMR; P52440; -.
DR   DNASU; 3289485; -.
DR   GeneID; 3289485; -.
DR   KEGG; vg:3289485; -.
DR   Proteomes; UP000009246; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0019079; P:viral genome replication; IEA:InterPro.
DR   InterPro; IPR004997; Herpes_PAP.
DR   Pfam; PF03325; Herpes_PAP; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Reference proteome.
FT   CHAIN           1..364
FT                   /note="DNA polymerase processivity factor"
FT                   /id="PRO_0000116067"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          284..306
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          325..364
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..354
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   364 AA;  41553 MW;  64520FEDBADA6C37 CRC64;
     MDRSNREHHS HRDHREHRDS KEPPTMAFHM KTWKTINKPL RAFAKLLREN TTVTFTPQPA
     IIIQSAKNHL VLKLIIHAEC LYITDTDHFS TKTINNFVPL FDSFMGIISN PDVTKLYIQH
     DSDLYTRFLV TASDICAQAS IPCVNGQEIV RESGKSALRI DLDHSTVTEI LKWLAPVTKN
     KRSNKNEMTL AQIVVQVNPP SIKFLTDLNE IEFAHSGKVV FHDAKCMRLV LSSKNLQQAF
     STCAVLKSSC SLRAIAGKEY KLFLIAKNVF LTVEAYLSQE QVKDDPKFER QAKTEEKGEK
     NHKVEEGNNF FCKQETQHKI TSYMVPTKNG GTGTNFFNEK EDSESDDSAH FDYTPNSKRQ
     RCGM