ID   VPAP_HHV6Z              Reviewed;         366 AA.
AC   Q9QJ40;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   02-JUN-2021, entry version 48.
DE   RecName: Full=DNA polymerase processivity factor;
DE   AltName: Full=Phosphoprotein P41;
DE            Short=PP41;
DE   AltName: Full=Polymerase accessory protein;
DE            Short=PAP;
GN   Name=U27;
OS   Human herpesvirus 6B (strain Z29) (HHV-6 variant B) (Human B lymphotropic
OS   virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=36351;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10482553; DOI=10.1128/jvi.73.10.8040-8052.1999;
RA   Dominguez G., Dambaugh T.R., Stamey F.R., Dewhurst S., Inoue N.,
RA   Pellett P.E.;
RT   "Human herpesvirus 6B genome sequence: coding content and comparison with
RT   human herpesvirus 6A.";
RL   J. Virol. 73:8040-8052(1999).
CC   -!- FUNCTION: Accessory subunit of the DNA polymerase that acts to increase
CC       the processivity of polymerization. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae polymerase accessory protein
CC       family. {ECO:0000305}.
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DR   EMBL; AF157706; AAD49641.1; -; Genomic_DNA.
DR   RefSeq; NP_050208.1; NC_000898.1.
DR   SMR; Q9QJ40; -.
DR   PRIDE; Q9QJ40; -.
DR   DNASU; 1497029; -.
DR   GeneID; 1497029; -.
DR   KEGG; vg:1497029; -.
DR   Proteomes; UP000006930; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0019079; P:viral genome replication; IEA:InterPro.
DR   InterPro; IPR004997; Herpes_PAP.
DR   Pfam; PF03325; Herpes_PAP; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Phosphoprotein; Reference proteome.
FT   CHAIN           1..366
FT                   /note="DNA polymerase processivity factor"
FT                   /id="PRO_0000408449"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          286..366
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        286..311
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        312..340
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        341..356
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   366 AA;  41721 MW;  2C815CEAC8840A08 CRC64;
     MERGSRDHHR DHRDHREHRE LREPPTLAFH MKSWKTINKP LKAFTKLLKE NTTVTFTPQP
     SIIIQSAKNH LVQKLTIQAE CLFLSDTEHF LTKTINNHIP LFESFMNIIS NPEVTKLYIQ
     HDSDLYTRVL VTASDTCTQA SVPCVHGQEV VRDSGKSPLR IDLDHSTVSE VLKWLSPVTK
     TKRSGKSDAF MAHIIVQVNP PTIKFVTEMN ELEFSNSNKV IFYDVNNMRF NLSAKNLQQA
     LSMCAVIKTS CSLRTVAAKD CKLILTSKST LLTVEAFLTQ EQLKEESRFE RMGKQDDGKG
     DRNHKNEDGS ALASKQETQY KITNYMVPTK NGTAGSSLFN EKEDSESDDS MHFEYSSNPK
     RQRCVV