ID   VIRE_HELVI              Reviewed;          41 AA.
AC   P83416;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Virescein;
OS   Heliothis virescens (Tobacco budworm moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Heliothinae; Heliothis.
OX   NCBI_TaxID=7102 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, TISSUE
RP   SPECIFICITY, INDUCTION, AND MASS SPECTROMETRY.
RC   TISSUE=Hemolymph;
RA   Bulet P., Lamberty M., Brookhart G., Bushey D.;
RL   Submitted (JUL-2002) to UniProtKB.
CC   -!- FUNCTION: Has antibacterial activity against Gram-positive and Gram-
CC       negative bacteria. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- SUBUNIT: Monomer. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Hemolymph. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- INDUCTION: By bacterial infection. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- MASS SPECTROMETRY: Mass=4389.59; Method=MALDI;
CC       Evidence={ECO:0000269|Ref.1};
CC   -!- SIMILARITY: Belongs to the moricin family. {ECO:0000305}.
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DR   AlphaFoldDB; P83416; -.
DR   SMR; P83416; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.750; -; 1.
DR   InterPro; IPR009456; Moricin_fam.
DR   InterPro; IPR037043; Moricin_sf.
DR   Pfam; PF06451; Moricin; 1.
PE   1: Evidence at protein level;
KW   Amidation; Antibiotic; Antimicrobial; Direct protein sequencing; Immunity;
KW   Innate immunity; Secreted.
FT   CHAIN           1..41
FT                   /note="Virescein"
FT                   /id="PRO_0000127114"
FT   MOD_RES         41
FT                   /note="Histidine amide"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   41 AA;  4389 MW;  2BCB3F57BAAE0679 CRC64;
     GKIPIGAIKK AGKAIGKGLR AVNIASTAHD VYTFFKPKKR H