ID   CAH10_PONAB             Reviewed;         328 AA.
AC   Q5R4U0;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Carbonic anhydrase-related protein 10;
GN   Name=CA10;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Does not have a catalytic activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC       {ECO:0000305}.
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DR   EMBL; CR861151; CAH93226.1; -; mRNA.
DR   AlphaFoldDB; Q5R4U0; -.
DR   SMR; Q5R4U0; -.
DR   STRING; 9601.ENSPPYP00000009286; -.
DR   Ensembl; ENSPPYT00000009660; ENSPPYP00000009286; ENSPPYG00000008263.
DR   eggNOG; KOG0382; Eukaryota.
DR   GeneTree; ENSGT00940000155223; -.
DR   HOGENOM; CLU_039326_7_1_1; -.
DR   InParanoid; Q5R4U0; -.
DR   OMA; HKNQNAC; -.
DR   TreeFam; TF352926; -.
DR   Proteomes; UP000001595; Chromosome 17.
DR   GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd03121; alpha_CARP_X_XI_like; 1.
DR   Gene3D; 3.10.200.10; -; 1.
DR   InterPro; IPR041878; Alpha_CARP_X/XI.
DR   InterPro; IPR018423; CA10.
DR   InterPro; IPR001148; CA_dom.
DR   InterPro; IPR036398; CA_dom_sf.
DR   InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR   PANTHER; PTHR18952; PTHR18952; 1.
DR   PANTHER; PTHR18952:SF91; PTHR18952:SF91; 1.
DR   Pfam; PF00194; Carb_anhydrase; 1.
DR   SMART; SM01057; Carb_anhydrase; 1.
DR   SUPFAM; SSF51069; SSF51069; 1.
DR   PROSITE; PS51144; ALPHA_CA_2; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..328
FT                   /note="Carbonic anhydrase-related protein 10"
FT                   /id="PRO_0000077439"
FT   DOMAIN          31..301
FT                   /note="Alpha-carbonic anhydrase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01134"
SQ   SEQUENCE   328 AA;  37563 MW;  B20BFEC1800422B4 CRC64;
     MEIVWEVLFL LQANFIVCIS AQQNSPKIHE GWWAYKEVVQ GSFVPVPSFW GLVNSAWNLC
     SVGKRQSPVN IETSHMIFDP FLTPLRINTG GRKVSGTMYN TGRHVSLRLD KEHLVNISGG
     PMTYSHRLEE IRLHFGSEDS QGSEHLLNGQ AFSGEVQLIH YNHELYTNVT EAAKSPNGLV
     VVSIFIKVSD SSNPFLNRML NRDTITRITY KNDAYLLQGL NIEELYPETS SFITYDGSMT
     IPPCYETASW IIMNKPVYIT RMQMHSLRLL SQNQPSQIFL SMSDNFRPVQ PLNNRCIRTN
     INFSLQGKDC PNNRAQKLQY RVNEWLLK