ID   URTF_STAHJ              Reviewed;         395 AA.
AC   Q4L846;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Probable uridylyltransferase SH0870;
DE            EC=2.7.7.-;
GN   OrderedLocusNames=SH0870;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- SIMILARITY: Belongs to the UDPGP type 1 family. {ECO:0000305}.
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DR   EMBL; AP006716; BAE04179.1; -; Genomic_DNA.
DR   RefSeq; WP_011275182.1; NC_007168.1.
DR   AlphaFoldDB; Q4L846; -.
DR   SMR; Q4L846; -.
DR   STRING; 279808.SH0870; -.
DR   EnsemblBacteria; BAE04179; BAE04179; SH0870.
DR   KEGG; sha:SH0870; -.
DR   eggNOG; COG4284; Bacteria.
DR   HOGENOM; CLU_025603_1_2_9; -.
DR   OMA; QPDVLKF; -.
DR   OrthoDB; 710317at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0070569; F:uridylyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR039741; UDP-sugar_pyrophosphorylase.
DR   InterPro; IPR002618; UDPGP_fam.
DR   PANTHER; PTHR11952; PTHR11952; 1.
DR   Pfam; PF01704; UDPGP; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase; Transferase.
FT   CHAIN           1..395
FT                   /note="Probable uridylyltransferase SH0870"
FT                   /id="PRO_0000271317"
FT   BINDING         99..102
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         113
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         178
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         204
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         235
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         344
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
SQ   SEQUENCE   395 AA;  45030 MW;  2B34144B106B665D CRC64;
     MLDQNQLKKY NQEHLSEYEK LMSSNEKEKL ESKVNELDLE SIQQLFQDLY VNRQSISDVS
     SVSEVKYQRK TELTDQEGAK YEQKGIEAIR NGEFAVLLMA GGQGTRLGYK GPKGSFEIKG
     VSLFELQARQ LLKLKKETGH LINWYIMTSD INHEETLSYF EQHDYFGYNP DNVHFFKQEN
     MVALCETGQL VLNEQGYIME TPNGNGGVFK SLEKNGYLDK MASDGVKFIF LNNIDNVLVK
     VLDPLFAGFT VVNDCDVTSK SIQPKDGESV GRLVNQNSKD TVLEYSELDE AVANTFDNAN
     IGIHAFKVAF IKQAVNNDLP YHLAVKKLKQ LDEDFGVVEK PTLKFELFYF DIFRYATSFV
     TLQVNREDEF SPLKNKEGKD SVETATSDLE RLNLI