ID   UREF_GLOC7              Reviewed;         232 AA.
AC   B7K911;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   OrderedLocusNames=PCC7424_4416;
OS   Gloeothece citriformis (strain PCC 7424) (Cyanothece sp. (strain PCC
OS   7424)).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Chroococcales;
OC   Aphanothecaceae; Gloeothece; Gloeothece citriformis.
OX   NCBI_TaxID=65393;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7424;
RX   PubMed=21972240; DOI=10.1128/mbio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
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DR   EMBL; CP001291; ACK72780.1; -; Genomic_DNA.
DR   RefSeq; WP_015956364.1; NC_011729.1.
DR   AlphaFoldDB; B7K911; -.
DR   SMR; B7K911; -.
DR   STRING; 65393.PCC7424_4416; -.
DR   EnsemblBacteria; ACK72780; ACK72780; PCC7424_4416.
DR   KEGG; cyc:PCC7424_4416; -.
DR   eggNOG; COG0830; Bacteria.
DR   HOGENOM; CLU_049215_4_0_3; -.
DR   OMA; HCVAYET; -.
DR   OrthoDB; 1942614at2; -.
DR   Proteomes; UP000002384; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..232
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_1000145113"
SQ   SEQUENCE   232 AA;  25795 MW;  C00CC2F0DF775A2D CRC64;
     MNHSLLAPKL ALMQLSDSFF PSGSFTLSHG LEALAQGEQI HSIKDLEIFL QILLHNKLGT
     TDLVALIHAY RGSKREDLDA VREADHQLFA QTLIEKNREM GRKSGRALLM VARETWQDTQ
     LETLEKETAK GTINGLHPII FAVVGRVAGL SETDTGLAFL HSFITGLLGA AIRLNIIGHL
     QAQKILLKLA PDLETTYQKA TEINLNEMFS CTPLIDIAQM NHQNLDYRLF AN