ID   UREE_PSEAE              Reviewed;         167 AA.
AC   Q9HUS2;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Urease accessory protein UreE {ECO:0000255|HAMAP-Rule:MF_00822};
GN   Name=ureE {ECO:0000255|HAMAP-Rule:MF_00822}; OrderedLocusNames=PA4891;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Involved in urease metallocenter assembly. Binds nickel.
CC       Probably functions as a nickel donor during metallocenter assembly.
CC       {ECO:0000255|HAMAP-Rule:MF_00822}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00822}.
CC   -!- SIMILARITY: Belongs to the UreE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00822}.
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DR   EMBL; AE004091; AAG08276.1; -; Genomic_DNA.
DR   PIR; E83034; E83034.
DR   RefSeq; NP_253578.1; NC_002516.2.
DR   RefSeq; WP_003095526.1; NZ_QZGE01000002.1.
DR   AlphaFoldDB; Q9HUS2; -.
DR   SMR; Q9HUS2; -.
DR   STRING; 287.DR97_2242; -.
DR   PaxDb; Q9HUS2; -.
DR   DNASU; 882294; -.
DR   EnsemblBacteria; AAG08276; AAG08276; PA4891.
DR   GeneID; 882294; -.
DR   KEGG; pae:PA4891; -.
DR   PATRIC; fig|208964.12.peg.5124; -.
DR   PseudoCAP; PA4891; -.
DR   HOGENOM; CLU_093757_2_0_6; -.
DR   InParanoid; Q9HUS2; -.
DR   OMA; AYDARCK; -.
DR   PhylomeDB; Q9HUS2; -.
DR   BioCyc; PAER208964:G1FZ6-5005-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   GO; GO:0019627; P:urea metabolic process; IEA:InterPro.
DR   CDD; cd00571; UreE; 1.
DR   HAMAP; MF_00822; UreE; 1.
DR   InterPro; IPR012406; UreE.
DR   InterPro; IPR007864; UreE_C_dom.
DR   InterPro; IPR004029; UreE_N.
DR   InterPro; IPR036118; UreE_N_sf.
DR   Pfam; PF05194; UreE_C; 1.
DR   Pfam; PF02814; UreE_N; 1.
DR   PIRSF; PIRSF036402; Ureas_acces_UreE; 1.
DR   SMART; SM00988; UreE_N; 1.
DR   SUPFAM; SSF69287; SSF69287; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel; Nickel insertion; Reference proteome.
FT   CHAIN           1..167
FT                   /note="Urease accessory protein UreE"
FT                   /id="PRO_0000223421"
SQ   SEQUENCE   167 AA;  18812 MW;  5EE28865E247DDFC CRC64;
     MLVIHQRLPA RSPRWDEELH LTYEARSKSR LRCFAASGEE VGLFLERGQP PLADGDCLEA
     RDGRLVRVVA RSERLLHVTC ASPLELTRAA YHLGNRHVAL QVGDGWLRLL DDYVLKAMLE
     QLGATVEAIE APFQPEHGAY GGGHHHSHHG EAEFNYAPRL HQFGVRR