ID   URED_SYNR3              Reviewed;         310 AA.
AC   A5GWV3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   OrderedLocusNames=SynRCC307_2459;
OS   Synechococcus sp. (strain RCC307).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=316278;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCC307;
RG   Genoscope;
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAK29362.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CT978603; CAK29362.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_043738481.1; NC_009482.1.
DR   AlphaFoldDB; A5GWV3; -.
DR   SMR; A5GWV3; -.
DR   STRING; 316278.SynRCC307_2459; -.
DR   EnsemblBacteria; CAK29362; CAK29362; SynRCC307_2459.
DR   KEGG; syr:SynRCC307_2459; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_4_0_3; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000001115; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..310
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340528"
SQ   SEQUENCE   310 AA;  33592 MW;  E0E6A57F866DB4FA CRC64;
     MTDTPNQLPP WRGSVSLDFE LAADGTTQWQ GGARSPLKLL RHFTAGDGRC VMPLLHTAGG
     LVGGDQLEIA LHAAAGSRSF LTSVAAQKIY GSRGRSRVQP QGRWAQITLQ AELEAGADLE
     WLPQETVVFA GALLEQQQQI TVAPGASWLG ADVVRLGRTA RGEDLGAGRF CNSLSIRRGE
     QWSVVERLSL EQEQLPNPHG MGGEPVLGTL IWIAPEPLEN EQLAQLLKGG RADREGLSGT
     MAIGPLEPGL IARYRGGSSQ AARLWFFRLW RRIRAVQGLS EPSWPRTWPF QEAELALNPE
     PATTATTAAR