ID   URED_ALIF1              Reviewed;         287 AA.
AC   Q5E725;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=VF_0676;
OS   Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Aliivibrio.
OX   NCBI_TaxID=312309;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700601 / ES114;
RX   PubMed=15703294; DOI=10.1073/pnas.0409900102;
RA   Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R.,
RA   Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E.,
RA   Stevens A., Visick K., Whistler C., Greenberg E.P.;
RT   "Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with
RT   pathogenic congeners.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000020; AAW85171.1; -; Genomic_DNA.
DR   RefSeq; WP_011261404.1; NC_006840.2.
DR   RefSeq; YP_204059.1; NC_006840.2.
DR   AlphaFoldDB; Q5E725; -.
DR   SMR; Q5E725; -.
DR   STRING; 312309.VF_0676; -.
DR   EnsemblBacteria; AAW85171; AAW85171; VF_0676.
DR   KEGG; vfi:VF_0676; -.
DR   PATRIC; fig|312309.11.peg.669; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CHHVLVH; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000000537; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..287
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340531"
SQ   SEQUENCE   287 AA;  32479 MW;  436218D7134ED9AD CRC64;
     MPKINTSSSG WLADISLFYE KRGTNTKLVH REQVGPLMVQ RPFYPETGIA HTYLLHPPGG
     VVGGDQLNIN IHVSPQAHSL LTTPGATKFY RSSGATSSQT QNLTVESDGF LEWLPQENIF
     FPDSQAQLKT QVELHKNAHF IGWEMNCFGR PVLDEIFENG FVTGRTNIKV DDQLLLSESM
     YIDSIDEIKH AAGMRHYPML GNLYIYPASE ALEEKLRTLI DENFHEQPEL FGSSNPICGI
     TEIDGLLVIR YLGHQTEPMM ACFSTLWQHT RQHWLGKLPE VPRIWAT