UL95_HCMVA
ID UL95_HCMVA Reviewed; 531 AA.
AC P16801; Q7M6J6;
DT 01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1990, sequence version 1.
DT 02-JUN-2021, entry version 59.
DE RecName: Full=Protein UL95;
GN Name=UL95;
OS Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX NCBI_TaxID=10360;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=2161319; DOI=10.1007/978-3-642-74980-3_6;
RA Chee M.S., Bankier A.T., Beck S., Bohni R., Brown C.M., Cerny R.,
RA Horsnell T., Hutchison C.A. III, Kouzarides T., Martignetti J.A.,
RA Preddie E., Satchwell S.C., Tomlinson P., Weston K.M., Barrell B.G.;
RT "Analysis of the protein-coding content of the sequence of human
RT cytomegalovirus strain AD169.";
RL Curr. Top. Microbiol. Immunol. 154:125-169(1990).
RN [2]
RP GENOME REANNOTATION.
RX PubMed=12533697; DOI=10.1099/vir.0.18606-0;
RA Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J.,
RA McGeoch D.J., Hayward G.S.;
RT "The human cytomegalovirus genome revisited: comparison with the chimpanzee
RT cytomegalovirus genome.";
RL J. Gen. Virol. 84:17-28(2003).
RN [3]
RP ERRATUM OF PUBMED:12533697.
RA Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J.,
RA McGeoch D.J., Hayward G.S.;
RL J. Gen. Virol. 84:1053-1053(2003).
CC -!- FUNCTION: Participates in the expression of late viral mRNAs. Expressed
CC before viral DNA replication, UL95 assembles at the viral pre-
CC replication complexes (pre-RCs) containing the early viral protein
CC UL44.
CC -!- SUBCELLULAR LOCATION: Host nucleus. Note=Recruited to nuclear
CC replication compartments.
CC -!- SIMILARITY: Belongs to the herpesviridae UL95 family. {ECO:0000305}.
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DR EMBL; X17403; CAA35369.1; -; Genomic_DNA.
DR EMBL; BK000394; DAA00192.1; -; Genomic_DNA.
DR PIR; S09859; S09859.
DR PRIDE; P16801; -.
DR Proteomes; UP000008991; Genome.
DR Proteomes; UP000008992; Genome.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR004280; Herpes_UL95.
DR Pfam; PF03038; Herpes_UL95; 1.
PE 3: Inferred from homology;
KW Early protein; Host nucleus; Reference proteome.
FT CHAIN 1..531
FT /note="Protein UL95"
FT /id="PRO_0000116248"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 531 AA; 57214 MW; 16B3D83043695644 CRC64;
MMAAAVVRAE VRRQRREERK KMAAARTTED PPENHVVADV ARGTGAVTRS SSSSLVVSSS
SASGSDESSS ASPLSFPVSS PSTAVRSPGS AGVSTSLCSV ERMVELSAQS PAADFSVSEA
WRFEEAVNMA LVACEAVSPY DRFRLIETPD ENFLLVTNVI PRESAEVPVL DSSSSGGDSG
PEDKKKNVGN KTAGEKNGGG SRAKRRRRRR APKNDAATPS FLRRHDVLER FAAAAKPLPS
LCVRDYALRN ADRVTYDGEL IYGSYLLYRK AHVELSLSSN KVQHVEAVLR QVYTPGLLDH
HNVCDVEALL WLLYCGPRSF CARDTCFGRE KNGCPFPALL PKLFYEPVRD YMTYMNLAEL
YVFVWYRGYE FPAPTPQATT AGGGGGSGGG GGAGACAVET SASAGRVDDA GDEVHLPLKP
VSLDRLREVL QAVRGRFSGR EVPAWPASSR TCLLCALYSQ NRLCLDLARD EARTVSYSPI
VIQDCAAAVT DVTLSHILPG QSTVSLFPVY HVGKLLDALS LNDAGLITLN L
