CA100_HUMAN
ID CA100_HUMAN Reviewed; 147 AA.
AC Q5SVJ3; Q5SVJ4;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Uncharacterized protein C1orf100;
GN Name=C1orf100;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A.,
RA Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C.,
RA Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.,
RA Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C.,
RA Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W.,
RA Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J.,
RA Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J.,
RA Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y.,
RA Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J.,
RA Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S.,
RA Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K.,
RA Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R.,
RA Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M.,
RA Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S.,
RA Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J.,
RA Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W.,
RA McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S.,
RA Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M.,
RA White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H.,
RA Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E.,
RA Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G.,
RA Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5SVJ3-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5SVJ3-2; Sequence=VSP_022710;
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DR EMBL; AL645465; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC054479; -; NOT_ANNOTATED_CDS; mRNA.
DR CCDS; CCDS31079.1; -. [Q5SVJ3-1]
DR CCDS; CCDS60465.1; -. [Q5SVJ3-2]
DR RefSeq; NP_001012988.1; NM_001012970.2. [Q5SVJ3-1]
DR RefSeq; NP_001263277.1; NM_001276348.1. [Q5SVJ3-2]
DR AlphaFoldDB; Q5SVJ3; -.
DR STRING; 9606.ENSP00000311218; -.
DR iPTMnet; Q5SVJ3; -.
DR PhosphoSitePlus; Q5SVJ3; -.
DR BioMuta; C1orf100; -.
DR MassIVE; Q5SVJ3; -.
DR PaxDb; Q5SVJ3; -.
DR PeptideAtlas; Q5SVJ3; -.
DR PRIDE; Q5SVJ3; -.
DR Antibodypedia; 34712; 37 antibodies from 7 providers.
DR DNASU; 200159; -.
DR Ensembl; ENST00000308105.5; ENSP00000311218.4; ENSG00000173728.11. [Q5SVJ3-1]
DR Ensembl; ENST00000366537.5; ENSP00000355495.1; ENSG00000173728.11. [Q5SVJ3-2]
DR GeneID; 200159; -.
DR KEGG; hsa:200159; -.
DR MANE-Select; ENST00000308105.5; ENSP00000311218.4; NM_001012970.3; NP_001012988.1.
DR UCSC; uc001iah.5; human. [Q5SVJ3-1]
DR CTD; 200159; -.
DR DisGeNET; 200159; -.
DR GeneCards; C1orf100; -.
DR HGNC; HGNC:30435; C1orf100.
DR HPA; ENSG00000173728; Tissue enriched (testis).
DR neXtProt; NX_Q5SVJ3; -.
DR OpenTargets; ENSG00000173728; -.
DR PharmGKB; PA142672484; -.
DR VEuPathDB; HostDB:ENSG00000173728; -.
DR eggNOG; ENOG502STJK; Eukaryota.
DR GeneTree; ENSGT00390000017364; -.
DR HOGENOM; CLU_149432_0_0_1; -.
DR InParanoid; Q5SVJ3; -.
DR OMA; DWDQKLA; -.
DR OrthoDB; 1403113at2759; -.
DR PhylomeDB; Q5SVJ3; -.
DR TreeFam; TF337910; -.
DR PathwayCommons; Q5SVJ3; -.
DR BioGRID-ORCS; 200159; 9 hits in 1035 CRISPR screens.
DR ChiTaRS; C1orf100; human.
DR GenomeRNAi; 200159; -.
DR Pharos; Q5SVJ3; Tdark.
DR PRO; PR:Q5SVJ3; -.
DR Proteomes; UP000005640; Chromosome 1.
DR RNAct; Q5SVJ3; protein.
DR Bgee; ENSG00000173728; Expressed in left testis and 97 other tissues.
DR Genevisible; Q5SVJ3; HS.
DR InterPro; IPR037668; C1orf100.
DR PANTHER; PTHR31763; PTHR31763; 1.
DR Pfam; PF17670; DUF5530; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..147
FT /note="Uncharacterized protein C1orf100"
FT /id="PRO_0000274315"
FT VAR_SEQ 52..83
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_022710"
SQ SEQUENCE 147 AA; 17617 MW; A6ABB448B016B82D CRC64;
MTAIRLREFI ERRPVIPPSI FIAHQGRDVQ GYYPGQLARL HFDHSAKRAP RPLIDLTIPP
KTKYHYQPQL DQQTLIRYIC LRRHSKPAEP WYKETTYRRD YSLPFYEIDW NQKLATVSLN
PRPLNSLPEL YCCEERSSFE RNAFKLK
