ID   TTR16_CAEEL             Reviewed;         132 AA.
AC   P55955; Q9XWL2;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2002, sequence version 2.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Transthyretin-like protein 16;
DE   AltName: Full=Unknown spot 4 protein from 2D-page;
DE   Flags: Precursor;
GN   Name=ttr-16; ORFNames=Y5F2A.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   PROTEIN SEQUENCE OF 20-42.
RC   STRAIN=Bristol N2;
RX   PubMed=9150941; DOI=10.1002/elps.1150180337;
RA   Bini L., Heid H., Liberatori S., Geier G., Pallini V., Zwilling R.;
RT   "Two-dimensional gel electrophoresis of Caenorhabditis elegans homogenates
RT   and identification of protein spots by microsequencing.";
RL   Electrophoresis 18:557-562(1997).
RN   [3]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-23, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=12754521; DOI=10.1038/nbt829;
RA   Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J.,
RA   Kasai K., Takahashi N., Isobe T.;
RT   "Lectin affinity capture, isotope-coded tagging and mass spectrometry to
RT   identify N-linked glycoproteins.";
RL   Nat. Biotechnol. 21:667-672(2003).
RN   [4]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-23, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RX   PubMed=15888633; DOI=10.1093/glycob/cwi075;
RA   Fan X., She Y.-M., Bagshaw R.D., Callahan J.W., Schachter H., Mahuran D.J.;
RT   "Identification of the hydrophobic glycoproteins of Caenorhabditis
RT   elegans.";
RL   Glycobiology 15:952-964(2005).
RN   [5]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-23, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=17761667; DOI=10.1074/mcp.m600392-mcp200;
RA   Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA   Taoka M., Takahashi N., Isobe T.;
RT   "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT   elegans and suggests an atypical translocation mechanism for integral
RT   membrane proteins.";
RL   Mol. Cell. Proteomics 6:2100-2109(2007).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the nematode transthyretin-like family.
CC       {ECO:0000305}.
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DR   EMBL; AL032641; CAA21645.1; -; Genomic_DNA.
DR   PIR; T27247; T27247.
DR   RefSeq; NP_502060.1; NM_069659.5.
DR   AlphaFoldDB; P55955; -.
DR   SMR; P55955; -.
DR   BioGRID; 43102; 14.
DR   STRING; 6239.Y5F2A.1; -.
DR   iPTMnet; P55955; -.
DR   EPD; P55955; -.
DR   PaxDb; P55955; -.
DR   PeptideAtlas; P55955; -.
DR   EnsemblMetazoa; Y5F2A.1.1; Y5F2A.1.1; WBGene00012382.
DR   GeneID; 178002; -.
DR   CTD; 178002; -.
DR   WormBase; Y5F2A.1; CE19022; WBGene00012382; ttr-16.
DR   eggNOG; ENOG502R6UF; Eukaryota.
DR   HOGENOM; CLU_121109_0_0_1; -.
DR   InParanoid; P55955; -.
DR   OMA; THNCNPS; -.
DR   OrthoDB; 1566606at2759; -.
DR   PhylomeDB; P55955; -.
DR   PRO; PR:P55955; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00012382; Expressed in larva and 4 other tissues.
DR   GO; GO:0009986; C:cell surface; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.3330; -; 1.
DR   InterPro; IPR001534; Transthyretin-like.
DR   InterPro; IPR038479; Transthyretin-like_sf.
DR   PANTHER; PTHR21700; PTHR21700; 1.
DR   Pfam; PF01060; TTR-52; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Glycoprotein; Reference proteome; Secreted;
KW   Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000269|PubMed:9150941"
FT   CHAIN           20..132
FT                   /note="Transthyretin-like protein 16"
FT                   /id="PRO_0000036249"
FT   CARBOHYD        23
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:12754521,
FT                   ECO:0000269|PubMed:15888633, ECO:0000269|PubMed:17761667"
SQ   SEQUENCE   132 AA;  14693 MW;  FBC0A2698FA25A11 CRC64;
     MRSLVVCLLL AACALECTAR LQNVTVKGVA VCNKKRLANV EVQLYEKDTL DPDDLLDTKK
     TDAEGEFSVY GEEDETHAIA PYLLITHSCN PSKPNCVRIG RYLVPEDKIG GTYDMTYVTL
     DIKVHGEKEK CQ