ID   TSN13_RAT               Reviewed;         204 AA.
AC   Q5FVL6;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Tetraspanin-13;
DE            Short=Tspan-13;
DE   AltName: Full=Transmembrane 4 superfamily member 13;
GN   Name=Tspan13; Synonyms=Tm4sf13;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lung;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
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DR   EMBL; BC089906; AAH89906.1; -; mRNA.
DR   RefSeq; NP_001013262.1; NM_001013244.1.
DR   AlphaFoldDB; Q5FVL6; -.
DR   SMR; Q5FVL6; -.
DR   STRING; 10116.ENSRNOP00000006752; -.
DR   GlyGen; Q5FVL6; 2 sites.
DR   iPTMnet; Q5FVL6; -.
DR   PhosphoSitePlus; Q5FVL6; -.
DR   PaxDb; Q5FVL6; -.
DR   PRIDE; Q5FVL6; -.
DR   Ensembl; ENSRNOT00000006752; ENSRNOP00000006752; ENSRNOG00000005046.
DR   GeneID; 366602; -.
DR   KEGG; rno:366602; -.
DR   UCSC; RGD:1311788; rat.
DR   CTD; 27075; -.
DR   RGD; 1311788; Tspan13.
DR   eggNOG; KOG3882; Eukaryota.
DR   GeneTree; ENSGT00940000157010; -.
DR   HOGENOM; CLU_088363_0_0_1; -.
DR   InParanoid; Q5FVL6; -.
DR   OMA; CPPCAPI; -.
DR   OrthoDB; 1203231at2759; -.
DR   PhylomeDB; Q5FVL6; -.
DR   TreeFam; TF323367; -.
DR   PRO; PR:Q5FVL6; -.
DR   Proteomes; UP000002494; Chromosome 6.
DR   Bgee; ENSRNOG00000005046; Expressed in stomach and 19 other tissues.
DR   Genevisible; Q5FVL6; RN.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; ISO:RGD.
DR   GO; GO:0005246; F:calcium channel regulator activity; ISO:RGD.
DR   GO; GO:1903169; P:regulation of calcium ion transmembrane transport; ISO:RGD.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR000301; Tetraspanin_animals.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   PANTHER; PTHR19282; PTHR19282; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   SUPFAM; SSF48652; SSF48652; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..204
FT                   /note="Tetraspanin-13"
FT                   /id="PRO_0000219260"
FT   TOPO_DOM        1..19
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        41..44
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        66..72
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        94..167
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        189..204
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         143
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9D8C2"
FT   CARBOHYD        113
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000250"
FT   CARBOHYD        137
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   204 AA;  22259 MW;  EF8A4E08D8CAE5E1 CRC64;
     MVCGGFSCSK NCLCALNLLY TLVSLLLIGI AAWGIGFGLI SSLRVVGVVI AVGIFLFLIA
     LVGLIGAVKH HQVLLFFYMI ILLLVFIVQF SVSCACLALN REQQGQLLEV GWNNTASARN
     DIQRNLNCCG FRNYNPNDTC PASCAKSNQK CSSCAPIIGE YAGEVLRFVG GIGLFFSFTE
     ILGVWLTYRY RNQKDPRANP SAFL