ID   TRRMC_MYCPN             Reviewed;         718 AA.
AC   P75452;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Putative type II restriction enzyme and methyltransferase RM.MpnORF110P C-terminus {ECO:0000303|PubMed:12654995};
GN   OrderedLocusNames=MPN_110; ORFNames=C09_orf718, MP044;
OS   Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS   pneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=272634;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
RN   [2]
RP   NOMENCLATURE, AND SUBTYPE.
RX   PubMed=12654995; DOI=10.1093/nar/gkg274;
RA   Roberts R.J., Belfort M., Bestor T., Bhagwat A.S., Bickle T.A.,
RA   Bitinaite J., Blumenthal R.M., Degtyarev S.K., Dryden D.T., Dybvig K.,
RA   Firman K., Gromova E.S., Gumport R.I., Halford S.E., Hattman S.,
RA   Heitman J., Hornby D.P., Janulaitis A., Jeltsch A., Josephsen J., Kiss A.,
RA   Klaenhammer T.R., Kobayashi I., Kong H., Krueger D.H., Lacks S.,
RA   Marinus M.G., Miyahara M., Morgan R.D., Murray N.E., Nagaraja V.,
RA   Piekarowicz A., Pingoud A., Raleigh E., Rao D.N., Reich N., Repin V.E.,
RA   Selker E.U., Shaw P.C., Stein D.C., Stoddard B.L., Szybalski W.,
RA   Trautner T.A., Van Etten J.L., Vitor J.M., Wilson G.G., Xu S.Y.;
RT   "A nomenclature for restriction enzymes, DNA methyltransferases, homing
RT   endonucleases and their genes.";
RL   Nucleic Acids Res. 31:1805-1812(2003).
RN   [3]
RP   DISCUSSION OF SEQUENCE.
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=23300489; DOI=10.1371/journal.pgen.1003191;
RA   Lluch-Senar M., Luong K., Llorens-Rico V., Delgado J., Fang G., Spittle K.,
RA   Clark T.A., Schadt E., Turner S.W., Korlach J., Serrano L.;
RT   "Comprehensive methylome characterization of Mycoplasma genitalium and
RT   Mycoplasma pneumoniae at single-base resolution.";
RL   PLoS Genet. 9:e1003191-e1003191(2013).
CC   -!- FUNCTION: Corresponds to the C-terminus of a putative G subtype type II
CC       restriction/methylase subunit. {ECO:0000303|PubMed:12654995}.
CC   -!- CAUTION: Could be the product of a pseudogene; while the translated
CC       protein of the N-terminal section has been identifed, this section has
CC       not been seen by mass spectrometry. {ECO:0000269|PubMed:23300489}.
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DR   EMBL; U00089; AAB95692.1; -; Genomic_DNA.
DR   PIR; S73370; S73370.
DR   RefSeq; NP_109798.1; NC_000912.1.
DR   RefSeq; WP_010874467.1; NC_000912.1.
DR   AlphaFoldDB; P75452; -.
DR   STRING; 272634.MPN_110; -.
DR   REBASE; 152957; Ssp60837ORF1696P.
DR   PRIDE; P75452; -.
DR   EnsemblBacteria; AAB95692; AAB95692; MPN_110.
DR   KEGG; mpn:MPN_110; -.
DR   PATRIC; fig|272634.6.peg.116; -.
DR   HOGENOM; CLU_384870_0_0_14; -.
DR   BioCyc; MPNE272634:G1GJ3-188-MON; -.
DR   Proteomes; UP000000808; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF04851; ResIII; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..718
FT                   /note="Putative type II restriction enzyme and
FT                   methyltransferase RM.MpnORF110P C-terminus"
FT                   /id="PRO_0000210648"
SQ   SEQUENCE   718 AA;  84850 MW;  3201D642E00E0754 CRC64;
     MKIRISLNIL AKFLDSFAHL LFLKNKEIYT PRKEQAACVE VLERYFQANP ENGRFLMNCK
     MRFGKCFTLY SYAQKNNINK ILILTFVPAV EESLKDDLNH IEKNYKFYTD DDLQKSNFDL
     KNQNEPYVVF LSLQNVLGKQ RIDGAKTDFD KERISKLQEI DFDLIVFDEY HYGANKKRTQ
     IKVEKVNKKI DNPEQQDNQD DAEEELASTF KLKDIKSKFQ FSYKQLVCLS GTPFSSLRNN
     EFSSKDQVFT YSYFDEQKAK SAENHPLKLG QYGIFPEMNI YCFELAEIFT AQEQEIFITP
     GKGKNKLPEI SFRKLFQTEN VSKESSKPVY RFVNENLVEK LIDSLIDKRK GFSHTPLSWE
     NIDKHKHSLL ILPTRVACFA LANLLKNHWY FENNDFQIIN MSESQFGNGK KALIELNKHL
     DEAKKTNKNT LTITVAKLTI GITVKEWSTV FFLKDLKGAE SYFQTIFRIQ TPYIKNCKNL
     KEICYVYDFN MYRCLEVTNE YSKQTQTDPK FSASWFQNLD KFLPIYLVRG DEIQKTDPEI
     LQKYEYFIMD KRAFSTRWMD ESNIIDIDVL CNVGQDEDAQ KILKKILAHK KFKSSKKKRE
     FEDVHLEKSP KSEAFSEGVR SGKDYAAEQG NVLEELENFW NFNQALEQKA KAEFQQKNFD
     DNEWNNYKKG FNFGVNKHFE DKVSIKKIVQ NKIKDFKKRK GRTTSTFKKW KWLYFWWE