ID   TRP_BPMU                Reviewed;         182 AA.
AC   Q9T1V8;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   23-FEB-2022, entry version 59.
DE   RecName: Full=Probable tail terminator protein;
DE            Short=TrP;
DE   AltName: Full=Gene product 37;
DE            Short=gp37;
DE   AltName: Full=Gene product K;
DE            Short=gpK;
GN   OrderedLocusNames=Mup37;
OS   Escherichia phage Mu (Bacteriophage Mu).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Muvirus.
OX   NCBI_TaxID=10677;
OH   NCBI_TaxID=543; Enterobacteriaceae.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11922669; DOI=10.1006/jmbi.2002.5437;
RA   Morgan G.J., Hatfull G.F., Casjens S., Hendrix R.W.;
RT   "Bacteriophage Mu genome sequence: analysis and comparison with Mu-like
RT   prophages in Haemophilus, Neisseria and Deinococcus.";
RL   J. Mol. Biol. 317:337-359(2002).
RN   [2]
RP   DISRUPTION PHENOTYPE.
RX   PubMed=3904174; DOI=10.1016/0042-6822(85)90388-5;
RA   Grundy F.J., Howe M.M.;
RT   "Morphogenetic structures present in lysates of amber mutants of
RT   bacteriophage Mu.";
RL   Virology 143:485-504(1985).
RN   [3]
RP   INDUCTION.
RX   PubMed=8293968; DOI=10.1093/genetics/135.3.619;
RA   Chiang L.W., Howe M.M.;
RT   "Mutational analysis of a C-dependent late promoter of bacteriophage Mu.";
RL   Genetics 135:619-629(1993).
RN   [4]
RP   IDENTIFICATION.
RX   PubMed=20946386; DOI=10.1111/j.1574-6968.2010.02128.x;
RA   Smith M.L., Avanigadda L.N., Liddell P.W., Kenwright K.M., Howe M.M.;
RT   "Identification of the J and K genes in the bacteriophage Mu genome
RT   sequence.";
RL   FEMS Microbiol. Lett. 313:29-32(2010).
RN   [5]
RP   FUNCTION.
RX   PubMed=19426744; DOI=10.1016/j.jmb.2009.04.072;
RA   Pell L.G., Liu A., Edmonds L., Donaldson L.W., Howell P.L., Davidson A.R.;
RT   "The X-ray crystal structure of the phage lambda tail terminator protein
RT   reveals the biologically relevant hexameric ring structure and demonstrates
RT   a conserved mechanism of tail termination among diverse long-tailed
RT   phages.";
RL   J. Mol. Biol. 389:938-951(2009).
RN   [6]
RP   REVIEW.
RX   PubMed=22297511; DOI=10.1007/978-1-4614-0980-9_5;
RA   Leiman P.G., Shneider M.M.;
RT   "Contractile tail machines of bacteriophages.";
RL   Adv. Exp. Med. Biol. 726:93-114(2012).
CC   -!- FUNCTION: May stop tail tube polymerization by capping the rapidly
CC       polymerizing tail tube once it has reached its requisite length and
CC       prevent its depolymerization. {ECO:0000305|PubMed:19426744}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host cytoplasm
CC       {ECO:0000305}. Note=Tail. {ECO:0000305}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       Expression of late genes is activated by the viral late transcription
CC       activator C. {ECO:0000269|PubMed:8293968}.
CC   -!- DISRUPTION PHENOTYPE: Accumulation of free heads as well as free tails
CC       longer than normal and variable in length.
CC       {ECO:0000269|PubMed:3904174}.
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DR   EMBL; AF083977; AAF01115.1; -; Genomic_DNA.
DR   RefSeq; NP_050641.1; NC_000929.1.
DR   GeneID; 2636286; -.
DR   KEGG; vg:2636286; -.
DR   Proteomes; UP000002611; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0098015; C:virus tail; IEA:UniProtKB-KW.
DR   GO; GO:0098003; P:viral tail assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR014972; Phage_Mu_Gp37.
DR   Pfam; PF08873; DUF1834; 1.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Late protein; Reference proteome;
KW   Viral release from host cell; Viral tail assembly; Viral tail protein;
KW   Virion.
FT   CHAIN           1..182
FT                   /note="Probable tail terminator protein"
FT                   /id="PRO_0000077830"
SQ   SEQUENCE   182 AA;  20556 MW;  0B9FC3E226996E20 CRC64;
     MLEETEAALL ARVRELFGAT LRQVEPLTGT WTNEDVHRLF LAPPSVFLAW MGCGEGRTRR
     EVESRWAFFV VAELLNGEPV NRPGIYQIVE RLIAGVNGQT FGPTTGMRLT QVRNLCDDNR
     INAGVVLYGV LFSGTTPLPS VVDLDSLDDY ERHWQTWKFP DETPEFAAHI NVNQEKDHDA
     EN