ID   TOLQ_SHIFL              Reviewed;         230 AA.
AC   P0ABV1; P05828;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Tol-Pal system protein TolQ {ECO:0000255|HAMAP-Rule:MF_02202};
GN   Name=tolQ {ECO:0000255|HAMAP-Rule:MF_02202};
GN   OrderedLocusNames=SF0560, S0573;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. Required, with TolR, for the
CC       proton motive force-dependent activation of TolA and for TolA-Pal
CC       interaction. {ECO:0000255|HAMAP-Rule:MF_02202}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_02202}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_02202}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_02202}.
CC   -!- SIMILARITY: Belongs to the ExbB/TolQ family. {ECO:0000255|HAMAP-
CC       Rule:MF_02202, ECO:0000305}.
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DR   EMBL; AE005674; AAN42204.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP16077.1; -; Genomic_DNA.
DR   RefSeq; NP_706497.1; NC_004337.2.
DR   RefSeq; WP_000131314.1; NZ_UIQL01000012.1.
DR   AlphaFoldDB; P0ABV1; -.
DR   SMR; P0ABV1; -.
DR   STRING; 198214.SF0560; -.
DR   EnsemblBacteria; AAN42204; AAN42204; SF0560.
DR   EnsemblBacteria; AAP16077; AAP16077; S0573.
DR   GeneID; 1023502; -.
DR   GeneID; 67413776; -.
DR   KEGG; sfl:SF0560; -.
DR   KEGG; sfx:S0573; -.
DR   PATRIC; fig|198214.7.peg.649; -.
DR   HOGENOM; CLU_053325_2_2_6; -.
DR   OMA; SWTYIFR; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043213; P:bacteriocin transport; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_02202; TolQ; 1.
DR   InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR   InterPro; IPR014163; Tol-Pal_TolQ.
DR   Pfam; PF01618; MotA_ExbB; 1.
DR   TIGRFAMs; TIGR02796; tolQ; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..230
FT                   /note="Tol-Pal system protein TolQ"
FT                   /id="PRO_0000145826"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02202"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02202"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02202"
SQ   SEQUENCE   230 AA;  25598 MW;  F4356F6C5B0F753C CRC64;
     MTDMNILDLF LKASLLVKLI MLILIGFSIA SWAIIIQRTR ILNAAAREAE AFEDKFWSGI
     ELSRLYQESQ GKRDNLTGSE QIFYSGFKEF VRLHRANSHA PEAVVEGASR AMRISMNREL
     ENLETHIPFL GTVGSISPYI GLFGTVWGIM HAFIALGAVK QATLQMVAPG IAEALIATAI
     GLFAAIPAVM AYNRLNQRVN KLELNYDNFM EEFTAILHRQ AFTVSESNKG