ID   TNP5_ECOLX              Reviewed;         994 AA.
AC   P08504;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Transposase for transposon Tn2501;
GN   Name=tnpA;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2827105; DOI=10.1093/nar/15.23.10049;
RA   Turner A.K., Grinsted J.;
RT   "DNA sequence of the transposase gene of the new category of class II
RT   transposon, Tn2501.";
RL   Nucleic Acids Res. 15:10049-10049(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-204.
RX   PubMed=3027041; DOI=10.1128/jb.169.2.624-631.1987;
RA   Michiels T., Cornelis G., Ellis K., Grinsted J.;
RT   "Tn2501, a component of the lactose transposon Tn951, is an example of a
RT   new category of class II transposable elements.";
RL   J. Bacteriol. 169:624-631(1987).
CC   -!- FUNCTION: Required for transposition of transposon Tn2501.
CC   -!- SIMILARITY: Belongs to the transposase 7 family. {ECO:0000305}.
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DR   EMBL; M15197; AAA27425.2; -; Genomic_DNA.
DR   EMBL; Y00502; CAA68555.1; -; Genomic_DNA.
DR   PIR; S06302; TQECT5.
DR   AlphaFoldDB; P08504; -.
DR   DIP; DIP-28126N; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR   InterPro; IPR025296; DUF4158.
DR   InterPro; IPR002513; Tn3_Tnp_DDE_dom.
DR   Pfam; PF01526; DDE_Tnp_Tn3; 1.
DR   Pfam; PF13700; DUF4158; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transposable element; Transposition.
FT   CHAIN           1..994
FT                   /note="Transposase for transposon Tn2501"
FT                   /id="PRO_0000075429"
SQ   SEQUENCE   994 AA;  112750 MW;  73E04895322AE1DA CRC64;
     MPRRQILSSE EQERLLVIPD DEIILTRMCF LNEQDIALIN KHRRPANRLG FAVLLCYLRG
     PGFIPDKSNV PHSSVISRIA SRLKLQPDLW PEYASREQTR WEHLTELYRY LKLSPFSRSL
     QKDCIRHLHP YAMRTDKGFM LAEEMLNWLH SNNVIFPSVD VIERTLAEAV TLADRAVFSA
     LTAQLEKQHK SALDSLLKSE GEQASRLAWL LQPPGKINGK NVLQHIDRLN SIAALGLPDG
     ITLSIHQNRL LKLAREGRKM SSRDLAKFTD VRRYATLVCV IQEAQATLTD EVIELHERIL
     GTLFSRAKRT QAERLQLTGK LIQSKLKQYV TVGQALLHAR ESGEDPWAAI EDVLPWQEFI
     NSLEETQFLS RKGNFDPLHL ITEKYSTLRK YAPRMLSALQ FIATPPAQTL SDALDTIRDM
     YRKQLRKVPP AAPTGFIPES WRKLVLTPSG IDRKYYEFCV MNELKGALRS GDIWVKGSRR
     YRNFDDYLIP AAEFEKSRHN DQLQLAVQTD CRAYLQARMT LLASRLEEVN AMALAGDLPD
     VDISDKGVKI TPLENSVPSG ASPFADLVYG MLPHPKITEI LEEVDNWTGF TRHFAHLKNN
     NVRPKDGRLL LTTILADGIN LGLTKMAESC PGATKSSLEG IQAWYIRDET YSAALAELVN
     AQKARPLAAF WGDGTTSSSD GQNFRVGSHG RYAGQVNLKY GQEPGVQIYT HISDQYSPFY
     AKVISRVRDS THVLDGLLYH ESDLEITEHY TDTAGFTEHV FALMHLLGFA FAPRIRDLHD
     KRLFIHGKAE RYPGLQSVIS TTSLNIKDIE AHWDEILRLA ASIKQGTVTA SLMIKKLASY
     PKQNGLAKAL REIGRIERTL FMLDWFRDPG LRRRVQAGLN KGEARNALAR AVFMHRLGEI
     RDRGLENQSY RASGLTLLTA AITLWNTVYI ERAIESLKRK GIPINNQLVS HLSPLGWEHI
     NLSGDYVWRN NIKLGSGKYR SLRTVDTELY KKQS