ID   TNNT_CAEEL              Reviewed;         405 AA.
AC   Q27371;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Troponin T;
GN   Name=mup-2; ORFNames=T22E5.5;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Bristol N2; TISSUE=Muscle;
RX   PubMed=8601585; DOI=10.1083/jcb.132.6.1061;
RA   Myers C.D., Goh P.-Y., Allen T.S., Bucher E.A., Bogaert T.;
RT   "Developmental genetic analysis of troponin T mutations in striated and
RT   nonstriated muscle cells of Caenorhabditis elegans.";
RL   J. Cell Biol. 132:1061-1077(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Troponin T is the tropomyosin-binding subunit of troponin,
CC       the thin filament regulatory complex which confers calcium-sensitivity
CC       to muscle actomyosin ATPase activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the troponin T family. {ECO:0000305}.
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DR   EMBL; U44759; AAA86906.1; -; mRNA.
DR   EMBL; FO081616; CCD72846.1; -; Genomic_DNA.
DR   PIR; T16922; T16922.
DR   RefSeq; NP_509076.1; NM_076675.6.
DR   AlphaFoldDB; Q27371; -.
DR   SMR; Q27371; -.
DR   BioGRID; 45844; 11.
DR   DIP; DIP-26592N; -.
DR   MINT; Q27371; -.
DR   STRING; 6239.T22E5.5.1; -.
DR   EPD; Q27371; -.
DR   PaxDb; Q27371; -.
DR   PeptideAtlas; Q27371; -.
DR   PRIDE; Q27371; -.
DR   EnsemblMetazoa; T22E5.5.1; T22E5.5.1; WBGene00003495.
DR   GeneID; 180914; -.
DR   KEGG; cel:CELE_T22E5.5; -.
DR   UCSC; T22E5.5.1; c. elegans.
DR   CTD; 180914; -.
DR   WormBase; T22E5.5; CE04994; WBGene00003495; mup-2.
DR   eggNOG; KOG3634; Eukaryota.
DR   HOGENOM; CLU_047178_0_0_1; -.
DR   InParanoid; Q27371; -.
DR   OMA; ARPPSDW; -.
DR   OrthoDB; 1193086at2759; -.
DR   PRO; PR:Q27371; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00003495; Expressed in larva and 4 other tissues.
DR   GO; GO:0005861; C:troponin complex; ISS:WormBase.
DR   GO; GO:0005523; F:tropomyosin binding; IBA:GO_Central.
DR   GO; GO:0007413; P:axonal fasciculation; IMP:WormBase.
DR   GO; GO:0048598; P:embryonic morphogenesis; IMP:WormBase.
DR   GO; GO:0007526; P:larval somatic muscle development; IMP:WormBase.
DR   GO; GO:0006936; P:muscle contraction; IBA:GO_Central.
DR   GO; GO:0030728; P:ovulation; IMP:WormBase.
DR   GO; GO:0006937; P:regulation of muscle contraction; IMP:WormBase.
DR   GO; GO:0045214; P:sarcomere organization; IMP:WormBase.
DR   Gene3D; 1.20.5.350; -; 1.
DR   InterPro; IPR027707; TNNT.
DR   InterPro; IPR001978; Troponin.
DR   InterPro; IPR038077; Troponin_sf.
DR   PANTHER; PTHR11521; PTHR11521; 1.
DR   Pfam; PF00992; Troponin; 1.
DR   SUPFAM; SSF90250; SSF90250; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..405
FT                   /note="Troponin T"
FT                   /id="PRO_0000186187"
FT   REGION          1..77
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          100..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          262..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          377..405
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..37
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..77
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        262..288
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        303..331
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        342..359
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   405 AA;  47041 MW;  1D3AC9EEB641C65B CRC64;
     MSDEEEVYSD EEVEEEEVEE TEEAPAEAEE PEETTEEVVA PPEVKERRAP VQEEKPPAEM
     TEAEIAMLAA KKRHEEEEAA KLLDYEQRRV LEKEQIEQEL RELKEKQEKR RAEREEDERQ
     FAERRRQDDE RRRKEEDERK AKADAEKIRK NEEKVRRQQM MAGAFNGRVE AGAGRNFTVA
     SKGDQAAQFG NLAQAKGGKD VMSKEQMEDA KRNFLAAVCR VQDVSGLLPN DLKERIRGLH
     ARIVKLEAEK YDLEKRRERQ DYDMKELHER QRQAARNKAL KKGLDPEEAA SSVHPPKITT
     ASKFDRQTDR RSYGDRRYLF ENPEEEKQAS LVRGTGRPPA EWGRKQNEEL EQIRKNLEPP
     KYVEQVKVEG ARAPVEPVPL FVPTDDFEPQ QVTEDPNVGE EVVVE