ID   TNNI3_CHICK             Reviewed;         168 AA.
AC   P27673;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Troponin I, cardiac muscle;
DE   AltName: Full=Cardiac troponin I;
DE   Flags: Fragment;
GN   Name=TNNI3;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1918073; DOI=10.1016/s0021-9258(18)55043-2;
RA   Hastings K.E., Koppe R.I., Marmur E., Bader D., Shimada Y., Toyota N.;
RT   "Structure and developmental expression of troponin I isoforms. cDNA clone
RT   analysis of avian cardiac troponin I mRNA.";
RL   J. Biol. Chem. 266:19659-19665(1991).
CC   -!- FUNCTION: Troponin I is the inhibitory subunit of troponin, the thin
CC       filament regulatory complex which confers calcium-sensitivity to
CC       striated muscle actomyosin ATPase activity.
CC   -!- SUBUNIT: Binds to actin and tropomyosin.
CC   -!- SIMILARITY: Belongs to the troponin I family. {ECO:0000305}.
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DR   EMBL; M73703; AAA49115.1; -; mRNA.
DR   AlphaFoldDB; P27673; -.
DR   SMR; P27673; -.
DR   VEuPathDB; HostDB:geneid_421161; -.
DR   InParanoid; P27673; -.
DR   PhylomeDB; P27673; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005861; C:troponin complex; IEA:InterPro.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0060048; P:cardiac muscle contraction; IBA:GO_Central.
DR   GO; GO:0006936; P:muscle contraction; IBA:GO_Central.
DR   GO; GO:0003009; P:skeletal muscle contraction; IBA:GO_Central.
DR   Gene3D; 1.20.5.350; -; 1.
DR   InterPro; IPR001978; Troponin.
DR   InterPro; IPR038077; Troponin_sf.
DR   Pfam; PF00992; Troponin; 1.
DR   SUPFAM; SSF90250; SSF90250; 1.
PE   2: Evidence at transcript level;
KW   Actin-binding; Muscle protein; Reference proteome.
FT   CHAIN           <1..168
FT                   /note="Troponin I, cardiac muscle"
FT                   /id="PRO_0000186156"
FT   REGION          128..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        128..161
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
SQ   SEQUENCE   168 AA;  18979 MW;  ABDD8F3E29C29540 CRC64;
     KLQLKTLLLQ RAKRELEREE QERAGEKQRH LGGLCPPPEL EGLGVAQLQE LCRELHARIA
     VDEERYDMGT RVSKNMAEME ELRRRVAGGR FVRPALRRVR LSADAMMAAL LGSKHRVGTD
     LRAGLRQVRK DDAEKESREV GDWRKNVDAL SGMEGRKKKF EAPGGGQG