BTF3_ARATH
ID BTF3_ARATH Reviewed; 165 AA.
AC Q9SMW7; Q93ZB5;
DT 16-MAR-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 153.
DE RecName: Full=Basic transcription factor 3 {ECO:0000303|PubMed:2320128};
DE Short=AtBTF3 {ECO:0000303|PubMed:2320128};
DE AltName: Full=Nascent polypeptide-associated complex subunit beta {ECO:0000255|RuleBase:RU361272};
GN Name=BTF3 {ECO:0000303|PubMed:2320128};
GN OrderedLocusNames=At1g17880 {ECO:0000312|Araport:AT1G17880};
GN ORFNames=F2H15.11 {ECO:0000312|EMBL:AAF97268.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:CAB56149.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=2320128; DOI=10.1038/344556a0;
RA Zheng X.M., Black D., Chambon P., Egly J.-M.;
RT "Sequencing and expression of complementary DNA for the general
RT transcription factor BTF3.";
RL Nature 344:556-559(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP INTERACTION WITH EIF(ISO)4E.
RX PubMed=15716105; DOI=10.1016/j.gene.2004.11.030;
RA Freire M.A.;
RT "Translation initiation factor (iso) 4E interacts with BTF3, the beta
RT subunit of the nascent polypeptide-associated complex.";
RL Gene 345:271-277(2005).
CC -!- SUBUNIT: Part of the nascent polypeptide-associated complex (NAC).
CC Interacts with EIF(ISO)4E (PubMed:15716105, PubMed:2320128).
CC {ECO:0000269|PubMed:15716105, ECO:0000305|PubMed:2320128}.
CC -!- INTERACTION:
CC Q9SMW7; O04663: EIF(ISO)4E; NbExp=2; IntAct=EBI-1770592, EBI-1770425;
CC -!- SIMILARITY: Belongs to the NAC-beta family. {ECO:0000305}.
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DR EMBL; AJ242970; CAB56149.1; -; mRNA.
DR EMBL; AC034106; AAF97268.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29647.1; -; Genomic_DNA.
DR EMBL; AF332407; AAG48770.1; -; mRNA.
DR EMBL; AY045793; AAK76467.1; -; mRNA.
DR EMBL; AY057667; AAL15298.1; -; mRNA.
DR EMBL; AY079361; AAL85092.1; -; mRNA.
DR EMBL; AY084522; AAM61090.1; -; mRNA.
DR PIR; A86314; A86314.
DR RefSeq; NP_173230.1; NM_101651.4.
DR AlphaFoldDB; Q9SMW7; -.
DR SMR; Q9SMW7; -.
DR IntAct; Q9SMW7; 3.
DR STRING; 3702.AT1G17880.1; -.
DR iPTMnet; Q9SMW7; -.
DR MetOSite; Q9SMW7; -.
DR PaxDb; Q9SMW7; -.
DR PRIDE; Q9SMW7; -.
DR ProteomicsDB; 240293; -.
DR EnsemblPlants; AT1G17880.1; AT1G17880.1; AT1G17880.
DR GeneID; 838367; -.
DR Gramene; AT1G17880.1; AT1G17880.1; AT1G17880.
DR KEGG; ath:AT1G17880; -.
DR Araport; AT1G17880; -.
DR TAIR; locus:2030963; AT1G17880.
DR eggNOG; KOG2240; Eukaryota.
DR HOGENOM; CLU_098726_0_0_1; -.
DR InParanoid; Q9SMW7; -.
DR OMA; KVGDCKH; -.
DR OrthoDB; 1435264at2759; -.
DR PhylomeDB; Q9SMW7; -.
DR PRO; PR:Q9SMW7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SMW7; baseline and differential.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005854; C:nascent polypeptide-associated complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0042788; C:polysomal ribosome; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR Gene3D; 2.20.70.30; -; 1.
DR InterPro; IPR039370; BTF3.
DR InterPro; IPR038187; NAC_A/B_dom_sf.
DR InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR PANTHER; PTHR10351; PTHR10351; 1.
DR Pfam; PF01849; NAC; 1.
DR SMART; SM01407; NAC; 1.
DR PROSITE; PS51151; NAC_AB; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..165
FT /note="Basic transcription factor 3"
FT /id="PRO_0000435658"
FT DOMAIN 33..97
FT /note="NAC-A/B"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00507"
FT REGION 120..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 53
FT /note="A -> P (in Ref. 4; AAL15298)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 165 AA; 17946 MW; C0DEFDC66D792110 CRC64;
MNREKLMKMA NTVRTGGKGT VRRKKKAVHK TNTTDDKRLQ STLKRIGVNS IPAIEEVNIF
KDDVVIQFIN PKVQASIAAN TWVVSGSPQT KKLQDILPQI ISQLGPDNMD NLKKLAEQFQ
KQASGEGNAA SATIQEEDDD DVPELVGETF ETAAEEKAPA AAASS
