ID   BSHC_BACC0              Reviewed;         538 AA.
AC   B7JK07;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Putative cysteine ligase BshC {ECO:0000255|HAMAP-Rule:MF_01867};
DE            EC=6.-.-.- {ECO:0000255|HAMAP-Rule:MF_01867};
GN   Name=bshC {ECO:0000255|HAMAP-Rule:MF_01867};
GN   OrderedLocusNames=BCAH820_3934;
OS   Bacillus cereus (strain AH820).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=405535;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AH820;
RA   Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A.,
RA   Ravel J., Sutton G.;
RT   "Genome sequence of Bacillus cereus AH820.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in bacillithiol (BSH) biosynthesis. May catalyze the
CC       last step of the pathway, the addition of cysteine to glucosamine
CC       malate (GlcN-Mal) to generate BSH. {ECO:0000255|HAMAP-Rule:MF_01867}.
CC   -!- SIMILARITY: Belongs to the BshC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01867}.
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DR   EMBL; CP001283; ACK90019.1; -; Genomic_DNA.
DR   RefSeq; WP_000403062.1; NC_011773.1.
DR   AlphaFoldDB; B7JK07; -.
DR   SMR; B7JK07; -.
DR   EnsemblBacteria; ACK90019; ACK90019; BCAH820_3934.
DR   KEGG; bcu:BCAH820_3934; -.
DR   HOGENOM; CLU_022249_1_0_9; -.
DR   OMA; TTGHQLN; -.
DR   Proteomes; UP000001363; Chromosome.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01867; BshC; 1.
DR   InterPro; IPR011199; Bacillithiol_biosynth_BshC.
DR   Pfam; PF10079; BshC; 1.
DR   PIRSF; PIRSF012535; UCP012535; 1.
DR   TIGRFAMs; TIGR03998; thiol_BshC; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Ligase.
FT   CHAIN           1..538
FT                   /note="Putative cysteine ligase BshC"
FT                   /id="PRO_0000378209"
FT   COILED          460..484
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01867"
SQ   SEQUENCE   538 AA;  62974 MW;  DD8B8C446FDCEA77 CRC64;
     MEIKEISVPQ QGVVADYMNG KKEIQSCFDY MLTEDAFKQR VQDLREREFF RQDLVTHLLE
     YNTKLQAGEA TIQNVKALGD ENTYVVIAGQ QAGLLTGPLY TIHKIISVLQ LAKEKEESLG
     VKVVPVFWIA GEDHDMDEIN HTFVTKNKKI KKTIFHDRNP KKASASESEL SLEDCRKWIE
     EIFKTYPETN FTKDVLQFVD DSLRKSNTYV DFFGHLIMKM FVNSGLILVD SHHPELRKLE
     VPFFKQIVSK YKEVQEGLHN QQEVIKELGY KPIIETKSNV VHIFMEIDNE RVLLEDNQGK
     FVGKDGTYSF SYEELIEEME RSPERFSNNV VTRPLMQEYV FPTLAFIGGP GELAYWSELQ
     QVFHTIGFRM PPVVPRITIT YIERDIATDL HDLQLQERDP FLNNVDKLRE NWLSNQIEEP
     IDDRFVEAKK EIMNIHTSLQ QFVKEIDPGL SAFAGKNEFK INEQIELLER MLKRNVEKKH
     EVELNKFRRI QFALRPLGAP QERVWNVCYY LNQFGLDFVD RVMEKPFSWN GKHHVIKL