BRXL3_ARATH
ID BRXL3_ARATH Reviewed; 370 AA.
AC Q5HZ09; Q5M752; Q5XVI3; Q9SYH6;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 2.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=Protein Brevis radix-like 3;
DE Short=AtBRXL3;
GN Name=BRXL3; OrderedLocusNames=At1g54180; ORFNames=F15I1.28;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 199-370.
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION.
RX PubMed=15031265; DOI=10.1101/gad.1187704;
RA Mouchel C.F., Briggs G.C., Hardtke C.S.;
RT "Natural genetic variation in Arabidopsis identifies BREVIS RADIX, a novel
RT regulator of cell proliferation and elongation in the root.";
RL Genes Dev. 18:700-714(2004).
RN [6]
RP GENE FAMILY, DISRUPTION PHENOTYPE, AND TISSUE SPECIFICITY.
RX PubMed=16514016; DOI=10.1104/pp.105.075382;
RA Briggs G.C., Mouchel C.F., Hardtke C.S.;
RT "Characterization of the plant-specific BREVIS RADIX gene family reveals
RT limited genetic redundancy despite high sequence conservation.";
RL Plant Physiol. 140:1306-1316(2006).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5HZ09-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5HZ09-2; Sequence=VSP_037243;
CC -!- TISSUE SPECIFICITY: Expressed in roots. {ECO:0000269|PubMed:16514016}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000269|PubMed:16514016}.
CC -!- SIMILARITY: Belongs to the BRX family. {ECO:0000305}.
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DR EMBL; AC005287; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC006577; AAD25792.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33058.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33059.1; -; Genomic_DNA.
DR EMBL; BT020396; AAV91342.1; -; mRNA.
DR EMBL; BT020515; AAW39016.1; -; mRNA.
DR EMBL; AY735539; AAU44409.1; -; mRNA.
DR EMBL; AY924710; AAX23785.1; -; mRNA.
DR PIR; A96583; A96583.
DR RefSeq; NP_001154422.1; NM_001160950.2. [Q5HZ09-2]
DR RefSeq; NP_175820.2; NM_104296.5. [Q5HZ09-1]
DR AlphaFoldDB; Q5HZ09; -.
DR SMR; Q5HZ09; -.
DR STRING; 3702.AT1G54180.1; -.
DR PaxDb; Q5HZ09; -.
DR PRIDE; Q5HZ09; -.
DR EnsemblPlants; AT1G54180.1; AT1G54180.1; AT1G54180. [Q5HZ09-1]
DR EnsemblPlants; AT1G54180.2; AT1G54180.2; AT1G54180. [Q5HZ09-2]
DR GeneID; 841858; -.
DR Gramene; AT1G54180.1; AT1G54180.1; AT1G54180. [Q5HZ09-1]
DR Gramene; AT1G54180.2; AT1G54180.2; AT1G54180. [Q5HZ09-2]
DR KEGG; ath:AT1G54180; -.
DR Araport; AT1G54180; -.
DR TAIR; locus:2014345; AT1G54180.
DR eggNOG; ENOG502QTYG; Eukaryota.
DR InParanoid; Q5HZ09; -.
DR OMA; ASTPKIW; -.
DR OrthoDB; 995616at2759; -.
DR PRO; PR:Q5HZ09; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q5HZ09; baseline and differential.
DR Genevisible; Q5HZ09; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR013591; Brevis_radix_dom.
DR InterPro; IPR044532; BRX-like.
DR InterPro; IPR027988; BRX_N.
DR PANTHER; PTHR46058; PTHR46058; 2.
DR Pfam; PF08381; BRX; 2.
DR Pfam; PF13713; BRX_N; 1.
DR PROSITE; PS51514; BRX; 2.
PE 2: Evidence at transcript level;
KW Alternative splicing; Nucleus; Reference proteome; Repeat.
FT CHAIN 1..370
FT /note="Protein Brevis radix-like 3"
FT /id="PRO_0000373824"
FT DOMAIN 140..221
FT /note="BRX 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00847"
FT DOMAIN 315..370
FT /note="BRX 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00847"
FT REGION 231..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 170..196
FT /note="RSTRFPYYRDQLLLWCRQGWVFWPQNC -> S (in isoform 2)"
FT /evidence="ECO:0000303|Ref.3"
FT /id="VSP_037243"
FT CONFLICT 290
FT /note="I -> T (in Ref. 3; AAV91342/AAU44409)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 370 AA; 41991 MW; ED2F031CB73A4CF0 CRC64;
MLTCIACTKQ LNTNNGGSTR EEDEEHGVIG TPRTKQAIKS LTSQLKDMAV KASGAYKNCK
PCSGTTNRNQ NRNYADSDAA SDSGRFHYSY QRAGTATSTP KIWGNEMESR LKGISSEEGT
PTSMSGRTES IVFMEDDEVK EWVAQVEPGV LITFVSLPQG GNDLKRIRFR STRFPYYRDQ
LLLWCRQGWV FWPQNCREMF NKWQAQKWWV ENFEKVMELY NVQFNQQSVP LQTPPVSEDG
GSQIQSVKDS PVTPPLERER PHRNIPGSSG FASTPKLSSI SGTKTETSSI DGSARSSSVD
RSEEVSVSNA SDMESEWVEQ DEPGIYITIR ALPDGNRELR RVRFSRDKFG ETHARLWWEQ
NRARIQQQYL
