ID   TF2B_SOYBN              Reviewed;         313 AA.
AC   P48513;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Transcription initiation factor IIB;
DE   AltName: Full=General transcription factor TFIIB;
GN   Name=TFIIB1;
OS   Glycine max (Soybean) (Glycine hispida).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC   Glycine subgen. Soja.
OX   NCBI_TaxID=3847;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8811869; DOI=10.1046/j.1365-313x.1996.10030561.x;
RA   Baldwin D.A., Gurley W.B.;
RT   "Isolation and characterization of cDNAs encoding transcription factor IIB
RT   from Arabidopsis and soybean.";
RL   Plant J. 10:561-568(1996).
CC   -!- FUNCTION: General factor that plays a major role in the activation of
CC       eukaryotic genes transcribed by RNA polymerase II.
CC   -!- SUBUNIT: Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB
CC       (DAB-complex) which is then recognized by polymerase II.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the TFIIB family. {ECO:0000305}.
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DR   EMBL; U31097; AAB09756.1; -; mRNA.
DR   PIR; T06440; T06440.
DR   RefSeq; NP_001238343.1; NM_001251414.1.
DR   AlphaFoldDB; P48513; -.
DR   SMR; P48513; -.
DR   STRING; 3847.GLYMA10G15700.1; -.
DR   PRIDE; P48513; -.
DR   EnsemblPlants; KRH33227; KRH33227; GLYMA_10G108600.
DR   GeneID; 548070; -.
DR   Gramene; KRH33227; KRH33227; GLYMA_10G108600.
DR   KEGG; gmx:548070; -.
DR   eggNOG; KOG1597; Eukaryota.
DR   HOGENOM; CLU_043736_1_1_1; -.
DR   InParanoid; P48513; -.
DR   OMA; RTQKDFA; -.
DR   OrthoDB; 729732at2759; -.
DR   Proteomes; UP000008827; Chromosome 10.
DR   Genevisible; P48513; GM.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0097550; C:transcription preinitiation complex; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017025; F:TBP-class protein binding; IBA:GO_Central.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR   GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR000812; TFIIB.
DR   InterPro; IPR023486; TFIIB_CS.
DR   InterPro; IPR013150; TFIIB_cyclin.
DR   InterPro; IPR013137; Znf_TFIIB.
DR   PANTHER; PTHR11618; PTHR11618; 1.
DR   Pfam; PF08271; TF_Zn_Ribbon; 1.
DR   Pfam; PF00382; TFIIB; 2.
DR   PRINTS; PR00685; TIFACTORIIB.
DR   SMART; SM00385; CYCLIN; 2.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00782; TFIIB; 1.
DR   PROSITE; PS51134; ZF_TFIIB; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..313
FT                   /note="Transcription initiation factor IIB"
FT                   /id="PRO_0000119304"
FT   REPEAT          116..193
FT                   /note="1"
FT   REPEAT          217..291
FT                   /note="2"
FT   ZN_FING         2..34
FT                   /note="TFIIB-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT   BINDING         6
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT   BINDING         9
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT   BINDING         26
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT   BINDING         29
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
SQ   SEQUENCE   313 AA;  34230 MW;  C1AE2F75A6E3AA0A CRC64;
     MSDAFCSDCK RQTEVVFDHS AGDTVCSECG LVLESHSIDE TSEWRTFANE SGDNDPNRVG
     GPSNPLLTDG GLSTVIAKPN GGGGGEFLSS SLGRWQNRGS NPDRALIQAF KTIATMSDRL
     GLVATIKDRA NEIYKRVEDQ KSSRGRNQDA LLAACLYIAC RQEDKPRTVK EICSVANGAT
     KKEIGRAKEY IVKQLGLENG NAVEMGTIHA GDFMRRFCSN LCMNNQAVKA AQEAVQKSEE
     FDIRRSPISI AAAVIYIITQ LSDDKKPLKD ISLATGVAEG TIRNSYKDLY PHVSKIIPNW
     YAKEEDLKNL CSP