TEG7_SUHVK
ID TEG7_SUHVK Reviewed; 236 AA.
AC Q85227;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 02-JUN-2021, entry version 37.
DE RecName: Full=Tegument protein UL51;
GN Name=UL51;
OS Suid herpesvirus 1 (strain Kaplan) (SuHV-1) (Pseudorabies virus (strain
OS Kaplan)).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX NCBI_TaxID=33703;
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7637001; DOI=10.1128/jvi.69.9.5560-5567.1995;
RA Baumeister J., Klupp B.G., Mettenleiter T.C.;
RT "Pseudorabies virus and equine herpesvirus 1 share a nonessential gene
RT which is absent in other herpesviruses and located adjacent to a highly
RT conserved gene cluster.";
RL J. Virol. 69:5560-5567(1995).
CC -!- FUNCTION: Plays several roles during the time course of infection,
CC including egress of virus particles from the perinuclear space and
CC secondary envelopment of cytoplasmic capsids that bud into specific
CC trans-Golgi network (TGN)-derived membranes.
CC {ECO:0000250|UniProtKB:P10235}.
CC -!- SUBUNIT: Oligomerizes. Interacts with UL7; this interaction mediates
CC UL7 incorporation to virions. {ECO:0000250|UniProtKB:P10235,
CC ECO:0000250|UniProtKB:P16823}.
CC -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250|UniProtKB:P10235}.
CC Host cytoplasm {ECO:0000250|UniProtKB:P10235}. Host Golgi apparatus
CC {ECO:0000250|UniProtKB:P10235}.
CC -!- PTM: Phosphorylated. {ECO:0000250|UniProtKB:P10235}.
CC -!- PTM: Palmitoylation is necessary for Golgi localization.
CC {ECO:0000250|UniProtKB:P10235}.
CC -!- SIMILARITY: Belongs to the herpesviridae UL51 family. {ECO:0000305}.
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DR EMBL; X87246; CAA60689.1; -; Genomic_DNA.
DR SMR; Q85227; -.
DR GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR InterPro; IPR007625; Herpes_UL51.
DR Pfam; PF04540; Herpes_UL51; 1.
PE 3: Inferred from homology;
KW Host cytoplasm; Host Golgi apparatus; Lipoprotein; Palmitate;
KW Phosphoprotein; Virion; Virion tegument.
FT CHAIN 1..236
FT /note="Tegument protein UL51"
FT /id="PRO_0000116103"
FT REGION 156..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 10
FT /note="S-palmitoyl cysteine; by host"
FT /evidence="ECO:0000250|UniProtKB:P10235"
SQ SEQUENCE 236 AA; 25049 MW; BDE42655C34C5CD5 CRC64;
MLGGIFSGWC GRRGRGRAYE PPDELRLRES LAVLNVILPA PLAAEDVMAS AEAARRLARA
DTLARTYQAC QRNLECLARH EASGDDGLDA VVAAHAANAR RLADTCLAAL MHLYLSVGAV
DADTDDLVEQ ALRMTAESNV VMSDVAVLER TLGLARRRQP APVRAAPAGL GLPVPAQPAP
RATAARPAPP PPPEEAGEDE EGDRPEDDAA PLLPPRAPAK TRPPEKARRL AEACKM