ID   TCX8_ARATH              Reviewed;         368 AA.
AC   Q700D0; A0MEW6; Q9LW71;
DT   11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=Protein tesmin/TSO1-like CXC 8;
DE            Short=AtTCX8;
GN   Name=TCX8; OrderedLocusNames=At3g16160; ORFNames=MSL1.20;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15208423; DOI=10.1104/pp.104.042176;
RA   Gong W., Shen Y.-P., Ma L.-G., Pan Y., Du Y.-L., Wang D.-H., Yang J.-Y.,
RA   Hu L.-D., Liu X.-F., Dong C.-X., Ma L., Chen Y.-H., Yang X.-Y., Gao Y.,
RA   Zhu D., Tan X., Mu J.-Y., Zhang D.-B., Liu Y.-L., Dinesh-Kumar S.P., Li Y.,
RA   Wang X.-P., Gu H.-Y., Qu L.-J., Bai S.-N., Lu Y.-T., Li J.-Y., Zhao J.-D.,
RA   Zuo J., Huang H., Deng X.-W., Zhu Y.-X.;
RT   "Genome-wide ORFeome cloning and analysis of Arabidopsis transcription
RT   factor genes.";
RL   Plant Physiol. 135:773-782(2004).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [5]
RP   GENE FAMILY, NOMENCLATURE, AND ZINC-BINDING.
RX   PubMed=18057042; DOI=10.1093/jxb/erm215;
RA   Andersen S.U., Algreen-Petersen R.G., Hoedl M., Jurkiewicz A.,
RA   Cvitanich C., Braunschweig U., Schauser L., Oh S.A., Twell D., Jensen E.O.;
RT   "The conserved cysteine-rich domain of a tesmin/TSO1-like protein binds
RT   zinc in vitro and TSO1 is required for both male and female fertility in
RT   Arabidopsis thaliana.";
RL   J. Exp. Bot. 58:3657-3670(2007).
CC   -!- FUNCTION: Plays a role in development of both male and female
CC       reproductive tissues. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- DOMAIN: The cysteine-rich domain CRC binds zinc in vitro.
CC   -!- SIMILARITY: Belongs to the lin-54 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK28561.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
CC       Sequence=BAB02682.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB012247; BAB02682.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002686; AEE75778.1; -; Genomic_DNA.
DR   EMBL; AJ630495; CAG25868.1; -; mRNA.
DR   EMBL; AY568667; AAS79557.1; -; mRNA.
DR   EMBL; DQ653089; ABK28561.1; ALT_SEQ; mRNA.
DR   RefSeq; NP_188237.2; NM_112486.3.
DR   AlphaFoldDB; Q700D0; -.
DR   SMR; Q700D0; -.
DR   BioGRID; 6195; 51.
DR   IntAct; Q700D0; 50.
DR   STRING; 3702.AT3G16160.1; -.
DR   PaxDb; Q700D0; -.
DR   PRIDE; Q700D0; -.
DR   EnsemblPlants; AT3G16160.1; AT3G16160.1; AT3G16160.
DR   GeneID; 820861; -.
DR   Gramene; AT3G16160.1; AT3G16160.1; AT3G16160.
DR   KEGG; ath:AT3G16160; -.
DR   Araport; AT3G16160; -.
DR   TAIR; locus:2093417; AT3G16160.
DR   eggNOG; KOG1171; Eukaryota.
DR   HOGENOM; CLU_810346_0_0_1; -.
DR   InParanoid; Q700D0; -.
DR   OMA; CKCINCK; -.
DR   OrthoDB; 704611at2759; -.
DR   PhylomeDB; Q700D0; -.
DR   PRO; PR:Q700D0; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q700D0; baseline and differential.
DR   Genevisible; Q700D0; AT.
DR   GO; GO:0005634; C:nucleus; IDA:TAIR.
DR   GO; GO:0000987; F:cis-regulatory region sequence-specific DNA binding; IPI:TAIR.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   InterPro; IPR005172; CRC.
DR   InterPro; IPR028307; Lin-54_fam.
DR   InterPro; IPR033467; Tesmin/TSO1-like_CXC.
DR   PANTHER; PTHR12446; PTHR12446; 2.
DR   Pfam; PF03638; TCR; 2.
DR   SMART; SM01114; CXC; 2.
DR   PROSITE; PS51634; CRC; 1.
PE   1: Evidence at protein level;
KW   Developmental protein; Metal-binding; Nucleus; Reference proteome; Zinc.
FT   CHAIN           1..368
FT                   /note="Protein tesmin/TSO1-like CXC 8"
FT                   /id="PRO_0000418173"
FT   DOMAIN          64..185
FT                   /note="CRC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00971"
SQ   SEQUENCE   368 AA;  41200 MW;  26CA422B8F0440F1 CRC64;
     MTGNADSGKI ATEKDPRKLV FTKLEVSPVF RESPVKELPL FPPISREHSE AKDKTDEEGI
     TSRKHKGCRC KQSKCLKLYC DCFASGVVCT DCDCVDCHNN SEKCDAREAA MVNVLGRNPN
     AFSEKALGSL TDNQCKAAPD TKPGLLSRGC KCKRTRCLKK YCECFQANLL CSDNCKCINC
     KNVSEAFQPP AFSAHNSPQV YRRRRDRELT EWNSCPAPLF SIPDNSIQNA LGSPMSCSPK
     LPYRKKRSLM GYTSTLLPDL GDLCSLLVAA SESATTTAED QNRIFTKPDD KEAIELSSES
     ESRNVEEEIQ SRGRLIELID VQYNGEEDSQ CKTKTSVNET DIYMEQERAV LETFRDCLQK
     FIKSRLES