TCX4_ARATH
ID TCX4_ARATH Reviewed; 639 AA.
AC Q84JZ8; Q9CAV1;
DT 11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Protein tesmin/TSO1-like CXC 4;
DE Short=AtTCX4;
GN Name=TCX4; OrderedLocusNames=At3g04850; ORFNames=T9J14.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, NOMENCLATURE, AND ZINC-BINDING.
RX PubMed=18057042; DOI=10.1093/jxb/erm215;
RA Andersen S.U., Algreen-Petersen R.G., Hoedl M., Jurkiewicz A.,
RA Cvitanich C., Braunschweig U., Schauser L., Oh S.A., Twell D., Jensen E.O.;
RT "The conserved cysteine-rich domain of a tesmin/TSO1-like protein binds
RT zinc in vitro and TSO1 is required for both male and female fertility in
RT Arabidopsis thaliana.";
RL J. Exp. Bot. 58:3657-3670(2007).
CC -!- FUNCTION: Plays a role in development of both male and female
CC reproductive tissues. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- DOMAIN: The cysteine-rich domain CRC binds zinc in vitro.
CC -!- SIMILARITY: Belongs to the lin-54 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG51411.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC009465; AAG51411.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE74144.1; -; Genomic_DNA.
DR EMBL; BT003926; AAO41973.1; -; mRNA.
DR EMBL; BT005010; AAO50543.1; -; mRNA.
DR RefSeq; NP_187136.3; NM_111357.4.
DR AlphaFoldDB; Q84JZ8; -.
DR SMR; Q84JZ8; -.
DR STRING; 3702.AT3G04850.1; -.
DR PaxDb; Q84JZ8; -.
DR PRIDE; Q84JZ8; -.
DR EnsemblPlants; AT3G04850.1; AT3G04850.1; AT3G04850.
DR GeneID; 819645; -.
DR Gramene; AT3G04850.1; AT3G04850.1; AT3G04850.
DR KEGG; ath:AT3G04850; -.
DR Araport; AT3G04850; -.
DR TAIR; locus:2114825; AT3G04850.
DR eggNOG; KOG1171; Eukaryota.
DR HOGENOM; CLU_012297_1_0_1; -.
DR InParanoid; Q84JZ8; -.
DR OMA; WVENSKT; -.
DR OrthoDB; 683850at2759; -.
DR PhylomeDB; Q84JZ8; -.
DR PRO; PR:Q84JZ8; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q84JZ8; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR005172; CRC.
DR InterPro; IPR033467; Tesmin/TSO1-like_CXC.
DR InterPro; IPR044522; TSO1-like.
DR PANTHER; PTHR46159; PTHR46159; 1.
DR Pfam; PF03638; TCR; 2.
DR SMART; SM01114; CXC; 2.
DR PROSITE; PS51634; CRC; 1.
PE 1: Evidence at protein level;
KW Developmental protein; Metal-binding; Nucleus; Reference proteome; Zinc.
FT CHAIN 1..639
FT /note="Protein tesmin/TSO1-like CXC 4"
FT /id="PRO_0000418169"
FT DOMAIN 451..576
FT /note="CRC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00971"
FT REGION 282..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 70974 MW; 4528F25B86A68EC5 CRC64;
MDTPDKNRIS AVSFCNFEDS PVFQYINDLS PIEPVKPGRP ENILHSLVFT SPSSSSSLFC
SPQLNSYRDS RFFIKRHRSL DLSSPVVLIG ETLKNSPDAL WEEKLKCRPE KLENVSEPKP
FKEQISLAIE LANSLKHGRD GCDIQMVSCD EVPMDADDEI GSGGGSRELS DELCRQSFDP
LDFDADSDGV LHTDEMEAES GFGKEVIMFD VADIQNYEQQ IPRTTDPRFY SLASEPQQFS
IYCNNSNYVE EREGSCSVQV AAGAPDINLS CSSKVAAIDS TAEAEDKEDK DLQPSGKQRS
VRRRCLTFDM GGSHKRIPLR DSTNDLPLDS TSINKAPSPQ NCLDTSKQDT DEILPIPRTI
GLHLNGFVNP SVSSGRKKKK IKDGQAFPST TFHYNIEDEF STPVSTKRDL VVFSDVKIME
PPERSVEGEC FDQLMAMENR QLSQGLDELG SCKRCKCRKS QCLKLYCECF SAGLFCGEPC
SCQNCFNKPI HEDLVMKSRE VIKARNPLAF APKVVSTSDT VIDLWVENSK TPASARHKRG
CNCRKSGCSK KYCECFMMGV GCSSNCRCMG CKNTFGHTNE QCAGDSDVVT INDEAKHYGD
HGDASRQNEE ILTSERNRLL LPGSVAFRSL TSLSNLSEL
