ID   TCTP_XENLA              Reviewed;         172 AA.
AC   Q7ZYF2;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   Name=tpt1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- INTERACTION:
CC       Q7ZYF2; Q5FWP4: chfr; NbExp=3; IntAct=EBI-1783711, EBI-1783502;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; BC043811; AAH43811.1; -; mRNA.
DR   RefSeq; XP_018102812.1; XM_018247323.1.
DR   AlphaFoldDB; Q7ZYF2; -.
DR   SMR; Q7ZYF2; -.
DR   BioGRID; 98081; 1.
DR   IntAct; Q7ZYF2; 1.
DR   MaxQB; Q7ZYF2; -.
DR   GeneID; 108708523; -.
DR   KEGG; xla:108708523; -.
DR   Xenbase; XB-GENE-866570; tpt1.L.
DR   OMA; IVYEADC; -.
DR   OrthoDB; 1439384at2759; -.
DR   Proteomes; UP000186698; Chromosome 2L.
DR   Bgee; 108708523; Expressed in lung and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   1: Evidence at protein level;
KW   Calcium; Cytoplasm; Reference proteome.
FT   CHAIN           1..172
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000211277"
FT   DOMAIN          1..172
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   172 AA;  19526 MW;  1F34F2B7B1E9D168 CRC64;
     MIIYKDCITE DEMFSDIYKI IETPDGMCLE VEGKVIQREE GAIDDALIGG NASAEFQEDD
     VGGSSLTSGV DIVMNHKLQE TGFTKDSYKN YIKDYVKQLK AHLEKTNPER VNTFMKGAQE
     TVKKILGNFK NYQFYTGERM NPDGMVGLLD YREDGITPFM IFFKDGLIIE KC