ID   TCTP_THEPA              Reviewed;         173 AA.
AC   Q4N938;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   Name=TCTP; OrderedLocusNames=TP01_0276;
OS   Theileria parva (East coast fever infection agent).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Theileriidae; Theileria.
OX   NCBI_TaxID=5875;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Muguga;
RX   PubMed=15994558; DOI=10.1126/science.1110439;
RA   Gardner M.J., Bishop R., Shah T., de Villiers E.P., Carlton J.M., Hall N.,
RA   Ren Q., Paulsen I.T., Pain A., Berriman M., Wilson R.J.M., Sato S.,
RA   Ralph S.A., Mann D.J., Xiong Z., Shallom S.J., Weidman J., Jiang L.,
RA   Lynn J., Weaver B., Shoaibi A., Domingo A.R., Wasawo D., Crabtree J.,
RA   Wortman J.R., Haas B., Angiuoli S.V., Creasy T.H., Lu C., Suh B.,
RA   Silva J.C., Utterback T.R., Feldblyum T.V., Pertea M., Allen J.,
RA   Nierman W.C., Taracha E.L.N., Salzberg S.L., White O.R., Fitzhugh H.A.,
RA   Morzaria S., Venter J.C., Fraser C.M., Nene V.;
RT   "Genome sequence of Theileria parva, a bovine pathogen that transforms
RT   lymphocytes.";
RL   Science 309:134-137(2005).
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; AAGK01000001; EAN33520.1; -; Genomic_DNA.
DR   RefSeq; XP_765803.1; XM_760710.1.
DR   AlphaFoldDB; Q4N938; -.
DR   SMR; Q4N938; -.
DR   STRING; 5875.XP_765803.1; -.
DR   PRIDE; Q4N938; -.
DR   EnsemblProtists; EAN33520; EAN33520; TP01_0276.
DR   GeneID; 3503393; -.
DR   KEGG; tpv:TP01_0276; -.
DR   VEuPathDB; PiroplasmaDB:TpMuguga_01g00276; -.
DR   eggNOG; KOG1727; Eukaryota.
DR   InParanoid; Q4N938; -.
DR   OMA; IVYEADC; -.
DR   Proteomes; UP000001949; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   3: Inferred from homology;
KW   Calcium; Cytoplasm; Reference proteome.
FT   CHAIN           1..173
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000252311"
FT   DOMAIN          1..173
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   173 AA;  19925 MW;  B301C595E63238D0 CRC64;
     MKVYKDLYSN DEVCSDAYDH HDPFDNADLS SVAFEVKTSK VPKGEEDYGI GYNDEEGADQ
     MNVDPNVEMV VDVVDKFGLQ SLSLTKKDYS SYIRKYIQRL VATLQEKNPE RVEPFKTTVS
     DFVKHVLANF EDFEFYVGES LDYEAGLVYA YYKGEEVSPR LVFLKDGLVE ERY