ID   TCTP_ANOGA              Reviewed;         171 AA.
AC   Q7QCK2;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 2.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Translationally-controlled tumor protein homolog;
DE            Short=TCTP;
GN   Name=Tctp {ECO:0000250|UniProtKB:Q9VGS2}; ORFNames=AGAP002667;
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7165;
RN   [1] {ECO:0000312|EMBL:EAA08161.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST {ECO:0000312|EMBL:EAA08161.2};
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA   Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA   Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA   Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA   Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA   Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA   Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA   Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA   Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA   Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA   Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA   McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA   O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA   Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA   Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA   Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA   Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA   Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA   Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA   Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
CC   -!- FUNCTION: Involved in calcium binding and microtubule stabilization.
CC       {ECO:0000250|UniProtKB:P13693}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P13693}.
CC   -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01133}.
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DR   EMBL; AAAB01008859; EAA08161.2; -; Genomic_DNA.
DR   RefSeq; XP_312257.2; XM_312257.3.
DR   AlphaFoldDB; Q7QCK2; -.
DR   SMR; Q7QCK2; -.
DR   STRING; 7165.AGAP002667-PA; -.
DR   PaxDb; Q7QCK2; -.
DR   GeneID; 1273293; -.
DR   KEGG; aga:AgaP_AGAP002667; -.
DR   CTD; 1273293; -.
DR   VEuPathDB; VectorBase:AGAP002667; -.
DR   eggNOG; KOG1727; Eukaryota.
DR   HOGENOM; CLU_095877_0_1_1; -.
DR   InParanoid; Q7QCK2; -.
DR   OMA; IVYEADC; -.
DR   OrthoDB; 1439384at2759; -.
DR   PhylomeDB; Q7QCK2; -.
DR   Proteomes; UP000007062; Chromosome 2R.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   Gene3D; 2.170.150.10; -; 1.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   InterPro; IPR011323; Mss4/transl-control_tumour.
DR   InterPro; IPR034737; TCTP.
DR   InterPro; IPR018103; Translation_control_tumour_CS.
DR   InterPro; IPR018105; Translational_control_tumour_p.
DR   PANTHER; PTHR11991; PTHR11991; 1.
DR   Pfam; PF00838; TCTP; 1.
DR   PRINTS; PR01653; TCTPROTEIN.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   PROSITE; PS01002; TCTP_1; 1.
DR   PROSITE; PS01003; TCTP_2; 1.
DR   PROSITE; PS51797; TCTP_3; 1.
PE   3: Inferred from homology;
KW   Calcium; Cytoplasm; Reference proteome.
FT   CHAIN           1..171
FT                   /note="Translationally-controlled tumor protein homolog"
FT                   /id="PRO_0000232399"
FT   DOMAIN          1..171
FT                   /note="TCTP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01133"
SQ   SEQUENCE   171 AA;  19547 MW;  EA0D81C5F69619EF CRC64;
     MKIWKDVFTG DEMFSDTYKV KLVDDVMYEV YGKHVSRTLG DVQLDGANPS AEEAEEGTES
     ATESGVDIVL NHRLVETGFS DKKQFTTYLK DYMKKLVTRL EEKSPGEVEV FKTNINKVMK
     DLLGRFKDLQ FFTGESMDCE GLIAMLEYRD IDGESVPVLL CFKHGLEEEK F