SWT11_ORYSI
ID SWT11_ORYSI Reviewed; 307 AA.
AC Q19VE6; Q19VE8;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Bidirectional sugar transporter SWEET11;
DE Short=OsSWEET11;
DE AltName: Full=Disease resistant allele Xa13;
GN Name=SWEET11; Synonyms=Os8N3, XA13; ORFNames=OsI_30035;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, TISSUE SPECIFICITY,
RP DEVELOPMENTAL STAGE, AND INDUCTION BY XANTHOMONAS ORYZAE.
RC STRAIN=cv. IR24, cv. IR64, and cv. IRBB13;
RX PubMed=16648463; DOI=10.1101/gad.1416306;
RA Chu Z., Yuan M., Yao J., Ge X., Yuan B., Xu C., Li X., Fu B., Li Z.,
RA Bennetzen J.L., Zhang Q., Wang S.;
RT "Promoter mutations of an essential gene for pollen development result in
RT disease resistance in rice.";
RL Genes Dev. 20:1250-1255(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [3]
RP FUNCTION.
RC STRAIN=cv. IR24;
RX PubMed=11606550; DOI=10.1093/genetics/159.2.757;
RA Li Z.-K., Sanchez A., Angeles E., Singh S., Domingo J., Huang N.,
RA Khush G.S.;
RT "Are the dominant and recessive plant disease resistance genes similar? A
RT case study of rice R genes and Xanthomonas oryzae pv. oryzae races.";
RL Genetics 159:757-765(2001).
RN [4]
RP FUNCTION, INDUCTION BY XANTHOMONAS ORYZAE, AND TISSUE SPECIFICITY.
RC STRAIN=cv. IR24, and cv. IRBB13;
RX PubMed=16798873; DOI=10.1073/pnas.0604088103;
RA Yang B., Sugio A., White F.F.;
RT "Os8N3 is a host disease-susceptibility gene for bacterial blight of
RT rice.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:10503-10508(2006).
RN [5]
RP INDUCTION BY PTHXO1.
RC STRAIN=cv. IR24, and cv. IRBB13;
RX PubMed=20345643; DOI=10.1111/j.1469-8137.2010.03217.x;
RA Roemer P., Recht S., Strauss T., Elsaesser J., Schornack S., Boch J.,
RA Wang S., Lahaye T.;
RT "Promoter elements of rice susceptibility genes are bound and activated by
RT specific TAL effectors from the bacterial blight pathogen, Xanthomonas
RT oryzae pv. oryzae.";
RL New Phytol. 187:1048-1057(2010).
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the plasma membrane (By similarity). Required for pollen viability.
CC Confers sensitivity to bacterial blight mediated by X.oryzae pv. oryzae
CC (Xoo) in its Xa13 allelic form (e.g. cv. IR24), probably by providing
CC the sugar required for the pathogen growth. However, a recessive
CC resistance can be associated with the xa13 allele (in which the
CC promoter is mutated leading to reduced induction upon pathogen
CC infection, e.g. cv. IRBB13), specifically toward Xoo Philippine race 6
CC and Indian race PXO8 (PubMed:11606550, PubMed:16648463,
CC PubMed:16798873). {ECO:0000250|UniProtKB:Q8L9J7,
CC ECO:0000269|PubMed:11606550, ECO:0000269|PubMed:16648463,
CC ECO:0000269|PubMed:16798873}.
CC -!- SUBUNIT: Forms homooligomers and/or heterooligomers.
CC {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8L9J7};
CC Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in panicles and anthers. Also
CC detected at low levels in leaves and roots.
CC {ECO:0000269|PubMed:16648463, ECO:0000269|PubMed:16798873}.
CC -!- DEVELOPMENTAL STAGE: Accumulates to high levels in pollen grains,
CC tapetal cells, and middle-layer cells of the anther wall. Also detected
CC at high levels in connective tissue cells and the connective vascular
CC element at the unicellular- to-bicellular pollen grain stages. At the
CC tricellular pollen grain stage, confined to the cells of connective
CC vascular elements. {ECO:0000269|PubMed:16648463}.
CC -!- INDUCTION: By the X.oryzae pv. oryzae (Xoo) transcription activator-
CC like effector (TALe) protein pthXo1 and, possibly, AvrXa7. The
CC induction by X.oryzae pv. oryzae (Xoo) PXO99 occurs only in the Xa13
CC allelic form that contains full promoter region.
CC {ECO:0000269|PubMed:16648463, ECO:0000269|PubMed:16798873,
CC ECO:0000269|PubMed:20345643}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000305}.
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DR EMBL; DQ421394; ABD78942.1; -; Genomic_DNA.
DR EMBL; DQ421395; ABD78943.1; -; Genomic_DNA.
DR EMBL; DQ421396; ABD78944.1; -; Genomic_DNA.
DR EMBL; CM000133; EEC83944.1; -; Genomic_DNA.
DR AlphaFoldDB; Q19VE6; -.
DR SMR; Q19VE6; -.
DR STRING; 39946.Q19VE6; -.
DR EnsemblPlants; BGIOSGA026582-TA; BGIOSGA026582-PA; BGIOSGA026582.
DR Gramene; BGIOSGA026582-TA; BGIOSGA026582-PA; BGIOSGA026582.
DR HOGENOM; CLU_048643_4_0_1; -.
DR OMA; IVGVHKI; -.
DR Proteomes; UP000007015; Chromosome 8.
DR GO; GO:0005887; C:integral component of plasma membrane; ISS:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; IDA:Gramene.
DR GO; GO:0008515; F:sucrose transmembrane transporter activity; IEA:EnsemblPlants.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; ISS:UniProtKB.
DR GO; GO:0006825; P:copper ion transport; ISS:UniProtKB.
DR GO; GO:0042742; P:defense response to bacterium; IMP:Gramene.
DR InterPro; IPR004316; SWEET_sugar_transpr.
DR Pfam; PF03083; MtN3_slv; 2.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Repeat; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..307
FT /note="Bidirectional sugar transporter SWEET11"
FT /id="PRO_0000404147"
FT TOPO_DOM 1..14
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 15..35
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 36..47
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 48..68
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 69..74
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..95
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 96..107
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 108..128
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 129..135
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 136..156
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 157..168
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..189
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 190..194
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 195..215
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 216..307
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 17..100
FT /note="MtN3/slv 1"
FT DOMAIN 136..219
FT /note="MtN3/slv 2"
FT CONFLICT 238
FT /note="A -> T (in Ref. 1; ABD78942)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 307 AA; 32978 MW; 6E505D8DA701B664 CRC64;
MAGGFLSMAN PAVTLSGVAG NIISFLVFLA PVATFLQVYK KKSTGGYSSV PYVVALFSSV
LWIFYALVKT NSRPLLTINA FGCGVEAAYI VLYLVYAPRR ARLRTLAFFL LLDVAAFALI
VVTTLYLVPK PHQVKFLGSV CLAFSMAVFV APLSIIFKVI KTKSVEFMPI GLSVCLTLSA
VAWFCYGLFT KDPYVMYPNV GGFFFSCVQM GLYFWYRKPR NTAVLPTTSD SMSPISAAAA
ATQRVIELPA GTHAFTILSV SPIPILGVHK VEVVAAEQAA DGVAAAAAAD KELLQNKPEV
IEITAAV
