STR12_ARATH
ID STR12_ARATH Reviewed; 299 AA.
AC Q93WI0; O23727; Q8LCM5;
DT 18-APR-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 125.
DE RecName: Full=Rhodanese-like/PpiC domain-containing protein 12, chloroplastic;
DE AltName: Full=Sulfurtransferase 12;
DE Short=AtStr12;
DE Flags: Precursor;
GN OrderedLocusNames=At5g19370; ORFNames=F7K24.120;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia; TISSUE=Leaf;
RX PubMed=9356517; DOI=10.1073/pnas.94.23.12722;
RA Babiychuk E., Fuangthong M., Van Montagu M., Inze D., Kushnir S.;
RT "Efficient gene tagging in Arabidopsis thaliana using a gene trap
RT approach.";
RL Proc. Natl. Acad. Sci. U.S.A. 94:12722-12727(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17408957; DOI=10.1016/j.plaphy.2007.02.005;
RA Bartels A., Mock H.P., Papenbrock J.;
RT "Differential expression of Arabidopsis sulfurtransferases under various
RT growth conditions.";
RL Plant Physiol. Biochem. 45:178-187(2007).
RN [7]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT SER-82, CLEAVAGE OF TRANSIT PEPTIDE
RP [LARGE SCALE ANALYSIS] AFTER ALA-81, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB06699.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; Z86095; CAB06699.1; ALT_SEQ; mRNA.
DR EMBL; AF296837; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED92692.1; -; Genomic_DNA.
DR EMBL; AF370165; AAK43980.1; -; mRNA.
DR EMBL; AY059127; AAL15233.1; -; mRNA.
DR EMBL; AY086512; AAM63512.1; -; mRNA.
DR PIR; T52622; T52622.
DR RefSeq; NP_568372.1; NM_121942.5.
DR AlphaFoldDB; Q93WI0; -.
DR SMR; Q93WI0; -.
DR STRING; 3702.AT5G19370.1; -.
DR iPTMnet; Q93WI0; -.
DR PaxDb; Q93WI0; -.
DR PRIDE; Q93WI0; -.
DR ProteomicsDB; 245223; -.
DR EnsemblPlants; AT5G19370.1; AT5G19370.1; AT5G19370.
DR GeneID; 832057; -.
DR Gramene; AT5G19370.1; AT5G19370.1; AT5G19370.
DR KEGG; ath:AT5G19370; -.
DR Araport; AT5G19370; -.
DR TAIR; locus:2150235; AT5G19370.
DR eggNOG; KOG2017; Eukaryota.
DR HOGENOM; CLU_056271_0_0_1; -.
DR InParanoid; Q93WI0; -.
DR OMA; AVEYSMC; -.
DR OrthoDB; 1397633at2759; -.
DR PhylomeDB; Q93WI0; -.
DR PRO; PR:Q93WI0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q93WI0; baseline and differential.
DR Genevisible; Q93WI0; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.
DR Gene3D; 3.10.50.40; -; 1.
DR Gene3D; 3.40.250.10; -; 1.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR000297; PPIase_PpiC.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR Pfam; PF00581; Rhodanese; 1.
DR SMART; SM00450; RHOD; 1.
DR SUPFAM; SSF52821; SSF52821; 1.
DR PROSITE; PS50198; PPIC_PPIASE_2; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 1: Evidence at protein level;
KW Acetylation; Chloroplast; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..81
FT /note="Chloroplast"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 82..299
FT /note="Rhodanese-like/PpiC domain-containing protein 12,
FT chloroplastic"
FT /id="PRO_0000416534"
FT DOMAIN 93..183
FT /note="PpiC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00278"
FT DOMAIN 205..297
FT /note="Rhodanese"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00173"
FT ACT_SITE 257
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00173"
FT MOD_RES 82
FT /note="N-acetylserine"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CONFLICT 5
FT /note="T -> A (in Ref. 5; AAM63512)"
FT /evidence="ECO:0000305"
FT CONFLICT 106
FT /note="N -> D (in Ref. 5; AAM63512)"
FT /evidence="ECO:0000305"
FT CONFLICT 165
FT /note="N -> D (in Ref. 5; AAM63512)"
FT /evidence="ECO:0000305"
FT CONFLICT 298
FT /note="T -> S (in Ref. 5; AAM63512)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 299 AA; 32980 MW; 1EFF898DDCFD1D5B CRC64;
MFRVTGTLSA ASSPAVAAAS FSAALRLSIT PTLAIASPPH LRWFSKFSRQ FLGGRISSLR
PRIPSPCPIR LSGFPALKMR ASFSSGSSGS SASREILVQH LLVKNNDVEL FAELQKKFLD
GEEMSDLAAE YSICPSKKDG GILGWVKLGQ MVPEFEEAAF KAELNQVVRC RTQFGLHLLQ
VLSEREPVKD IQVEELHSKM QDPVFMDEAQ LIDVREPNEI EIASLPGFKV FPLRQFGTWA
PDITSKLNPE KDTFVLCKVG GRSMQVANWL QSQGFKSVYN ITGGIQAYSL KVDPSIPTY
