STMN4_RAT
ID STMN4_RAT Reviewed; 189 AA.
AC P63043; O35414; O35415; O35416;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 31-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 143.
DE RecName: Full=Stathmin-4;
DE AltName: Full=Stathmin-like protein B3;
DE Short=RB3;
GN Name=Stmn4;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3), AND TISSUE SPECIFICITY.
RC STRAIN=Sprague-Dawley; TISSUE=Corpus striatum;
RX PubMed=9342231; DOI=10.1111/j.1432-1033.1997.t01-2-00794.x;
RA Ozon S., Maucuer A., Sobel A.;
RT "The stathmin family -- molecular and biological characterization of novel
RT mammalian proteins expressed in the nervous system.";
RL Eur. J. Biochem. 248:794-806(1997).
RN [2]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=15039434; DOI=10.1074/jbc.m313693200;
RA Nakao C., Itoh T.J., Hotani H., Mori N.;
RT "Modulation of the stathmin-like microtubule destabilizing activity of RB3,
RT a neuron-specific member of the SCG10 family, by its N-terminal domain.";
RL J. Biol. Chem. 279:23014-23021(2004).
RN [3]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=12111843; DOI=10.1002/jnr.10234;
RA Gavet O., El Messari S., Ozon S., Sobel A.;
RT "Regulation and subcellular localization of the microtubule-destabilizing
RT stathmin family phosphoproteins in cortical neurons.";
RL J. Neurosci. Res. 68:535-550(2002).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-90, PHOSPHORYLATION [LARGE
RP SCALE ANALYSIS] AT SER-54 (ISOFORM 3), AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22673903; DOI=10.1038/ncomms1871;
RA Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA Olsen J.V.;
RT "Quantitative maps of protein phosphorylation sites across 14 different rat
RT organs and tissues.";
RL Nat. Commun. 3:876-876(2012).
RN [5]
RP X-RAY CRYSTALLOGRAPHY (3.58 ANGSTROMS) OF 49-189 IN COMPLEX WITH TUBULIN
RP HETERODIMER, AND FUNCTION.
RX PubMed=15014504; DOI=10.1038/nature02393;
RA Ravelli R.B., Gigant B., Curmi P.A., Jourdain I., Lachkar S., Sobel A.,
RA Knossow M.;
RT "Insight into tubulin regulation from a complex with colchicine and a
RT stathmin-like domain.";
RL Nature 428:198-202(2004).
CC -!- FUNCTION: Exhibits microtubule-destabilizing activity.
CC {ECO:0000269|PubMed:12111843, ECO:0000269|PubMed:15014504,
CC ECO:0000269|PubMed:15039434}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:12111843}.
CC Cell projection, growth cone {ECO:0000269|PubMed:12111843}. Cell
CC projection, axon {ECO:0000269|PubMed:12111843}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1;
CC IsoId=P63043-1, O35414-1;
CC Sequence=Displayed;
CC Name=2; Synonyms=RB3';
CC IsoId=P63043-2, O35414-2;
CC Sequence=VSP_006281;
CC Name=3; Synonyms=RB3'';
CC IsoId=P63043-3, O35414-3;
CC Sequence=VSP_006280;
CC -!- TISSUE SPECIFICITY: Nervous tissue. {ECO:0000269|PubMed:15039434,
CC ECO:0000269|PubMed:9342231}.
CC -!- SIMILARITY: Belongs to the stathmin family. {ECO:0000305}.
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DR EMBL; AF026528; AAC95061.1; -; mRNA.
DR EMBL; AF026529; AAC95062.1; -; mRNA.
DR EMBL; AF026530; AAC95063.1; -; mRNA.
DR RefSeq; NP_001257785.1; NM_001270856.1. [P63043-1]
DR RefSeq; NP_001257787.1; NM_001270858.1. [P63043-2]
DR RefSeq; NP_062049.1; NM_019176.2. [P63043-3]
DR RefSeq; XP_006252213.1; XM_006252151.3. [P63043-3]
DR PDB; 1SA0; X-ray; 3.58 A; E=49-189.
DR PDB; 1SA1; X-ray; 4.20 A; E=49-189.
DR PDB; 1Z2B; X-ray; 4.10 A; E=49-189.
DR PDB; 3DU7; X-ray; 4.10 A; E=49-189.
DR PDB; 3E22; X-ray; 3.80 A; E=49-189.
DR PDB; 3HKB; X-ray; 3.65 A; E=49-189.
DR PDB; 3HKC; X-ray; 3.80 A; E=49-189.
DR PDB; 3HKD; X-ray; 3.70 A; E=49-189.
DR PDB; 3HKE; X-ray; 3.60 A; E=49-189.
DR PDB; 3N2G; X-ray; 4.00 A; E=49-189.
DR PDB; 3N2K; X-ray; 4.00 A; E=49-189.
DR PDB; 3RYC; X-ray; 2.10 A; E=49-189.
DR PDB; 3RYF; X-ray; 2.52 A; E=49-189.
DR PDB; 3RYH; X-ray; 2.80 A; E=49-189.
DR PDB; 3RYI; X-ray; 2.40 A; E=49-189.
DR PDB; 3UT5; X-ray; 2.73 A; E=49-189.
DR PDB; 4EB6; X-ray; 3.47 A; E=49-189.
DR PDB; 4I4T; X-ray; 1.80 A; E=49-189.
DR PDB; 4I50; X-ray; 2.30 A; E=49-189.
DR PDB; 4I55; X-ray; 2.20 A; E=49-189.
DR PDB; 4IHJ; X-ray; 2.00 A; E=49-189.
DR PDB; 4IIJ; X-ray; 2.60 A; E=49-189.
DR PDB; 4O2A; X-ray; 2.50 A; E=49-189.
DR PDB; 4O2B; X-ray; 2.30 A; E=49-189.
DR PDB; 4O4H; X-ray; 2.10 A; E=49-189.
DR PDB; 4O4I; X-ray; 2.40 A; E=49-189.
DR PDB; 4O4J; X-ray; 2.20 A; E=49-189.
DR PDB; 4O4L; X-ray; 2.20 A; E=49-189.
DR PDB; 4TUY; X-ray; 2.10 A; E=49-189.
DR PDB; 4TV8; X-ray; 2.10 A; E=49-189.
DR PDB; 4TV9; X-ray; 2.00 A; E=49-189.
DR PDB; 4X1I; X-ray; 3.11 A; E=49-189.
DR PDB; 4X1K; X-ray; 3.50 A; E=49-189.
DR PDB; 4X1Y; X-ray; 3.19 A; E=49-189.
DR PDB; 4X20; X-ray; 3.50 A; E=49-189.
DR PDB; 4YJ2; X-ray; 2.60 A; E=49-189.
DR PDB; 4YJ3; X-ray; 3.75 A; E=49-189.
DR PDB; 4ZHQ; X-ray; 2.55 A; E=49-189.
DR PDB; 4ZI7; X-ray; 2.51 A; E=49-189.
DR PDB; 4ZOL; X-ray; 2.50 A; E=49-189.
DR PDB; 5BMV; X-ray; 2.50 A; E=49-189.
DR PDB; 5C8Y; X-ray; 2.59 A; E=49-189.
DR PDB; 5CA0; X-ray; 2.50 A; E=49-189.
DR PDB; 5CA1; X-ray; 2.40 A; E=49-189.
DR PDB; 5CB4; X-ray; 2.19 A; E=49-189.
DR PDB; 5EZY; X-ray; 2.05 A; E=49-189.
DR PDB; 5FNV; X-ray; 2.61 A; E=49-189.
DR PDB; 5GON; X-ray; 2.48 A; E=50-185.
DR PDB; 5H74; X-ray; 2.60 A; E=49-189.
DR PDB; 5H7O; X-ray; 2.80 A; E=49-189.
DR PDB; 5IYZ; X-ray; 1.80 A; E=49-189.
DR PDB; 5J2T; X-ray; 2.20 A; E=49-189.
DR PDB; 5J2U; X-ray; 2.50 A; E=49-189.
DR PDB; 5JH7; X-ray; 2.25 A; E=49-189.
DR PDB; 5JQG; X-ray; 2.24 A; E=49-189.
DR PDB; 5JVD; X-ray; 2.39 A; E=49-189.
DR PDB; 5KX5; X-ray; 2.50 A; E=49-189.
DR PDB; 5LA6; X-ray; 2.10 A; E=49-189.
DR PDB; 5LOV; X-ray; 2.40 A; E=49-189.
DR PDB; 5LP6; X-ray; 2.90 A; E=49-189.
DR PDB; 5LXS; X-ray; 2.20 A; E=49-189.
DR PDB; 5LXT; X-ray; 1.90 A; E=49-189.
DR PDB; 5LYJ; X-ray; 2.40 A; E=49-189.
DR PDB; 5M7E; X-ray; 2.05 A; E=49-189.
DR PDB; 5M7G; X-ray; 2.25 A; E=49-189.
DR PDB; 5M8D; X-ray; 2.25 A; E=49-189.
DR PDB; 5M8G; X-ray; 2.15 A; E=49-189.
DR PDB; 5MF4; X-ray; 2.30 A; E=49-189.
DR PDB; 5NFZ; X-ray; 2.10 A; E=49-189.
DR PDB; 5NG1; X-ray; 2.20 A; E=49-189.
DR PDB; 5NJH; X-ray; 2.39 A; E=47-189.
DR PDB; 5O7A; X-ray; 2.50 A; E=49-189.
DR PDB; 5OSK; X-ray; 2.11 A; E=49-189.
DR PDB; 5OV7; X-ray; 2.40 A; E=49-189.
DR PDB; 5S4L; X-ray; 2.30 A; E=49-189.
DR PDB; 5S4M; X-ray; 2.15 A; E=49-189.
DR PDB; 5S4N; X-ray; 2.53 A; E=49-189.
DR PDB; 5S4O; X-ray; 2.30 A; E=49-189.
DR PDB; 5S4P; X-ray; 2.29 A; E=49-189.
DR PDB; 5S4Q; X-ray; 2.59 A; E=49-189.
DR PDB; 5S4R; X-ray; 2.35 A; E=49-189.
DR PDB; 5S4S; X-ray; 2.35 A; E=49-189.
DR PDB; 5S4T; X-ray; 2.27 A; E=49-189.
DR PDB; 5S4U; X-ray; 2.39 A; E=49-189.
DR PDB; 5S4V; X-ray; 2.30 A; E=49-189.
DR PDB; 5S4W; X-ray; 2.80 A; E=49-189.
DR PDB; 5S4X; X-ray; 2.53 A; E=49-189.
DR PDB; 5S4Y; X-ray; 2.30 A; E=49-189.
DR PDB; 5S4Z; X-ray; 2.10 A; E=49-189.
DR PDB; 5S50; X-ray; 3.10 A; E=49-189.
DR PDB; 5S51; X-ray; 2.40 A; E=49-189.
DR PDB; 5S52; X-ray; 2.83 A; E=49-189.
DR PDB; 5S53; X-ray; 2.75 A; E=49-189.
DR PDB; 5S54; X-ray; 2.40 A; E=49-189.
DR PDB; 5S55; X-ray; 2.30 A; E=49-189.
DR PDB; 5S56; X-ray; 2.25 A; E=49-189.
DR PDB; 5S57; X-ray; 2.45 A; E=49-189.
DR PDB; 5S58; X-ray; 2.30 A; E=49-189.
DR PDB; 5S59; X-ray; 2.60 A; E=49-189.
DR PDB; 5S5A; X-ray; 2.35 A; E=49-189.
DR PDB; 5S5B; X-ray; 2.30 A; E=49-189.
DR PDB; 5S5C; X-ray; 2.40 A; E=49-189.
DR PDB; 5S5D; X-ray; 1.90 A; E=49-189.
DR PDB; 5S5E; X-ray; 2.67 A; E=49-189.
DR PDB; 5S5F; X-ray; 2.24 A; E=49-189.
DR PDB; 5S5G; X-ray; 2.69 A; E=49-189.
DR PDB; 5S5H; X-ray; 2.50 A; E=49-189.
DR PDB; 5S5I; X-ray; 2.49 A; E=49-189.
DR PDB; 5S5J; X-ray; 2.25 A; E=49-189.
DR PDB; 5S5K; X-ray; 2.41 A; E=49-189.
DR PDB; 5S5L; X-ray; 2.25 A; E=49-189.
DR PDB; 5S5M; X-ray; 2.70 A; E=49-189.
DR PDB; 5S5N; X-ray; 2.90 A; E=49-189.
DR PDB; 5S5O; X-ray; 2.30 A; E=49-189.
DR PDB; 5S5P; X-ray; 2.79 A; E=49-189.
DR PDB; 5S5Q; X-ray; 2.05 A; E=49-189.
DR PDB; 5S5R; X-ray; 2.30 A; E=49-189.
DR PDB; 5S5S; X-ray; 2.36 A; E=49-189.
DR PDB; 5S5T; X-ray; 2.53 A; E=49-189.
DR PDB; 5S5U; X-ray; 2.50 A; E=49-189.
DR PDB; 5S5V; X-ray; 2.70 A; E=49-189.
DR PDB; 5S5W; X-ray; 2.35 A; E=49-189.
DR PDB; 5S5X; X-ray; 2.32 A; E=49-189.
DR PDB; 5S5Y; X-ray; 2.26 A; E=49-189.
DR PDB; 5S5Z; X-ray; 2.55 A; E=49-189.
DR PDB; 5S60; X-ray; 2.30 A; E=49-189.
DR PDB; 5S61; X-ray; 1.95 A; E=49-189.
DR PDB; 5S62; X-ray; 2.75 A; E=49-189.
DR PDB; 5S63; X-ray; 2.60 A; E=49-189.
DR PDB; 5S64; X-ray; 2.75 A; E=49-189.
DR PDB; 5S65; X-ray; 2.25 A; E=49-189.
DR PDB; 5S66; X-ray; 2.10 A; E=49-189.
DR PDB; 5S67; X-ray; 2.10 A; E=49-189.
DR PDB; 5SB8; X-ray; 2.30 A; E=49-189.
DR PDB; 5SB9; X-ray; 2.50 A; E=49-189.
DR PDB; 5SBA; X-ray; 2.25 A; E=49-189.
DR PDB; 5SBB; X-ray; 2.25 A; E=49-189.
DR PDB; 5SBC; X-ray; 2.32 A; E=49-189.
DR PDB; 5SBD; X-ray; 2.25 A; E=49-189.
DR PDB; 5SBE; X-ray; 2.75 A; E=49-189.
DR PDB; 5XAF; X-ray; 2.55 A; E=1-189.
DR PDB; 5XAG; X-ray; 2.56 A; E=1-189.
DR PDB; 5XHC; X-ray; 2.75 A; E=6-189.
DR PDB; 5XI5; X-ray; 2.81 A; E=6-189.
DR PDB; 5XI7; X-ray; 2.99 A; E=6-189.
DR PDB; 5XIW; X-ray; 2.90 A; E=49-189.
DR PDB; 5XKE; X-ray; 2.60 A; E=49-189.
DR PDB; 5XKF; X-ray; 2.80 A; E=49-189.
DR PDB; 5XKG; X-ray; 2.20 A; E=49-189.
DR PDB; 5XKH; X-ray; 2.25 A; E=49-189.
DR PDB; 5XLT; X-ray; 2.81 A; E=49-189.
DR PDB; 5XLZ; X-ray; 2.30 A; E=49-189.
DR PDB; 5XP3; X-ray; 2.30 A; E=49-189.
DR PDB; 5YL2; X-ray; 2.09 A; E=49-189.
DR PDB; 5YL4; X-ray; 2.64 A; E=49-189.
DR PDB; 5YLJ; X-ray; 2.70 A; E=49-189.
DR PDB; 5YLS; X-ray; 3.00 A; E=49-189.
DR PDB; 5YZ3; X-ray; 2.54 A; E=49-189.
DR PDB; 5Z4P; X-ray; 2.50 A; E=1-185.
DR PDB; 5Z4U; X-ray; 3.18 A; E=49-189.
DR PDB; 5ZXH; X-ray; 2.80 A; E=49-189.
DR PDB; 6AGK; X-ray; 2.80 A; E=49-189.
DR PDB; 6BS2; X-ray; 2.65 A; E=49-189.
DR PDB; 6D88; X-ray; 2.85 A; E=49-189.
DR PDB; 6EG5; X-ray; 2.45 A; E=49-189.
DR PDB; 6F7C; X-ray; 2.00 A; E=49-189.
DR PDB; 6FII; X-ray; 2.40 A; E=49-189.
DR PDB; 6FJF; X-ray; 2.40 A; E=49-189.
DR PDB; 6FJM; X-ray; 2.10 A; E=49-189.
DR PDB; 6FKJ; X-ray; 2.15 A; E=47-189.
DR PDB; 6FKL; X-ray; 2.10 A; E=47-189.
DR PDB; 6GF3; X-ray; 2.40 A; E=49-189.
DR PDB; 6GJ4; X-ray; 2.40 A; E=49-189.
DR PDB; 6GZE; X-ray; 2.49 A; E=1-189.
DR PDB; 6H9B; X-ray; 2.75 A; E=48-189.
DR PDB; 6HX8; X-ray; 2.40 A; E=49-189.
DR PDB; 6I5C; X-ray; 2.95 A; E=49-189.
DR PDB; 6JCJ; X-ray; 2.50 A; E=49-189.
DR PDB; 6K9V; X-ray; 2.54 A; E=49-189.
DR PDB; 6KNZ; X-ray; 2.48 A; E=49-189.
DR PDB; 6N47; X-ray; 2.60 A; E=49-189.
DR PDB; 6QQN; X-ray; 2.30 A; E=49-189.
DR PDB; 6QTN; X-ray; 1.90 A; E=49-189.
DR PDB; 6S9E; X-ray; 2.25 A; E=1-189.
DR PDB; 6SES; X-ray; 2.00 A; E=49-189.
DR PDB; 6TDE; X-ray; 2.29 A; E=49-189.
DR PDB; 6TH4; X-ray; 2.12 A; E=48-189.
DR PDB; 6TIS; X-ray; 2.30 A; E=47-189.
DR PDB; 6TIU; X-ray; 3.57 A; E=47-189.
DR PDB; 6TIY; X-ray; 2.29 A; E=47-189.
DR PDB; 6TIZ; X-ray; 2.20 A; E=47-189.
DR PDB; 6X1C; X-ray; 2.90 A; E=49-189.
DR PDB; 6X1E; X-ray; 2.90 A; E=49-189.
DR PDB; 6X1F; X-ray; 2.70 A; E=49-189.
DR PDB; 6XER; X-ray; 2.50 A; E=49-189.
DR PDB; 6XES; X-ray; 2.32 A; E=49-189.
DR PDB; 6XET; X-ray; 2.60 A; E=49-189.
DR PDB; 6Y4M; X-ray; 3.34 A; E=49-189.
DR PDB; 6Y4N; X-ray; 2.85 A; E=49-189.
DR PDB; 6Y6D; X-ray; 2.20 A; E=49-189.
DR PDB; 7AU5; X-ray; 2.20 A; E=49-189.
DR PDB; 7CBZ; X-ray; 2.61 A; E=1-189.
DR PDB; 7CDA; X-ray; 2.66 A; E=49-189.
DR PDB; 7CE6; X-ray; 2.69 A; E=49-189.
DR PDB; 7CE8; X-ray; 2.73 A; E=49-189.
DR PDB; 7CEK; X-ray; 2.70 A; E=49-189.
DR PDB; 7CLD; X-ray; 2.61 A; E=49-189.
DR PDB; 7CPQ; X-ray; 2.60 A; E=1-189.
DR PDB; 7DP8; X-ray; 2.45 A; E=49-189.
DR PDB; 7E4P; X-ray; 2.40 A; E=50-187.
DR PDB; 7E4Q; X-ray; 2.50 A; E=50-187.
DR PDB; 7E4R; X-ray; 2.60 A; E=50-187.
DR PDB; 7E4Y; X-ray; 2.71 A; E=50-187.
DR PDB; 7E4Z; X-ray; 2.69 A; E=50-187.
DR PDB; 7JFR; X-ray; 2.35 A; E=50-187.
DR PDB; 7L05; X-ray; 2.21 A; E=47-189.
DR PDB; 7LZ7; X-ray; 2.80 A; E=49-189.
DR PDB; 7LZ8; X-ray; 2.92 A; E=49-189.
DR PDB; 7OGN; X-ray; 2.20 A; E=1-189.
DR PDBsum; 1SA0; -.
DR PDBsum; 1SA1; -.
DR PDBsum; 1Z2B; -.
DR PDBsum; 3DU7; -.
DR PDBsum; 3E22; -.
DR PDBsum; 3HKB; -.
DR PDBsum; 3HKC; -.
DR PDBsum; 3HKD; -.
DR PDBsum; 3HKE; -.
DR PDBsum; 3N2G; -.
DR PDBsum; 3N2K; -.
DR PDBsum; 3RYC; -.
DR PDBsum; 3RYF; -.
DR PDBsum; 3RYH; -.
DR PDBsum; 3RYI; -.
DR PDBsum; 3UT5; -.
DR PDBsum; 4EB6; -.
DR PDBsum; 4I4T; -.
DR PDBsum; 4I50; -.
DR PDBsum; 4I55; -.
DR PDBsum; 4IHJ; -.
DR PDBsum; 4IIJ; -.
DR PDBsum; 4O2A; -.
DR PDBsum; 4O2B; -.
DR PDBsum; 4O4H; -.
DR PDBsum; 4O4I; -.
DR PDBsum; 4O4J; -.
DR PDBsum; 4O4L; -.
DR PDBsum; 4TUY; -.
DR PDBsum; 4TV8; -.
DR PDBsum; 4TV9; -.
DR PDBsum; 4X1I; -.
DR PDBsum; 4X1K; -.
DR PDBsum; 4X1Y; -.
DR PDBsum; 4X20; -.
DR PDBsum; 4YJ2; -.
DR PDBsum; 4YJ3; -.
DR PDBsum; 4ZHQ; -.
DR PDBsum; 4ZI7; -.
DR PDBsum; 4ZOL; -.
DR PDBsum; 5BMV; -.
DR PDBsum; 5C8Y; -.
DR PDBsum; 5CA0; -.
DR PDBsum; 5CA1; -.
DR PDBsum; 5CB4; -.
DR PDBsum; 5EZY; -.
DR PDBsum; 5FNV; -.
DR PDBsum; 5GON; -.
DR PDBsum; 5H74; -.
DR PDBsum; 5H7O; -.
DR PDBsum; 5IYZ; -.
DR PDBsum; 5J2T; -.
DR PDBsum; 5J2U; -.
DR PDBsum; 5JH7; -.
DR PDBsum; 5JQG; -.
DR PDBsum; 5JVD; -.
DR PDBsum; 5KX5; -.
DR PDBsum; 5LA6; -.
DR PDBsum; 5LOV; -.
DR PDBsum; 5LP6; -.
DR PDBsum; 5LXS; -.
DR PDBsum; 5LXT; -.
DR PDBsum; 5LYJ; -.
DR PDBsum; 5M7E; -.
DR PDBsum; 5M7G; -.
DR PDBsum; 5M8D; -.
DR PDBsum; 5M8G; -.
DR PDBsum; 5MF4; -.
DR PDBsum; 5NFZ; -.
DR PDBsum; 5NG1; -.
DR PDBsum; 5NJH; -.
DR PDBsum; 5O7A; -.
DR PDBsum; 5OSK; -.
DR PDBsum; 5OV7; -.
DR PDBsum; 5S4L; -.
DR PDBsum; 5S4M; -.
DR PDBsum; 5S4N; -.
DR PDBsum; 5S4O; -.
DR PDBsum; 5S4P; -.
DR PDBsum; 5S4Q; -.
DR PDBsum; 5S4R; -.
DR PDBsum; 5S4S; -.
DR PDBsum; 5S4T; -.
DR PDBsum; 5S4U; -.
DR PDBsum; 5S4V; -.
DR PDBsum; 5S4W; -.
DR PDBsum; 5S4X; -.
DR PDBsum; 5S4Y; -.
DR PDBsum; 5S4Z; -.
DR PDBsum; 5S50; -.
DR PDBsum; 5S51; -.
DR PDBsum; 5S52; -.
DR PDBsum; 5S53; -.
DR PDBsum; 5S54; -.
DR PDBsum; 5S55; -.
DR PDBsum; 5S56; -.
DR PDBsum; 5S57; -.
DR PDBsum; 5S58; -.
DR PDBsum; 5S59; -.
DR PDBsum; 5S5A; -.
DR PDBsum; 5S5B; -.
DR PDBsum; 5S5C; -.
DR PDBsum; 5S5D; -.
DR PDBsum; 5S5E; -.
DR PDBsum; 5S5F; -.
DR PDBsum; 5S5G; -.
DR PDBsum; 5S5H; -.
DR PDBsum; 5S5I; -.
DR PDBsum; 5S5J; -.
DR PDBsum; 5S5K; -.
DR PDBsum; 5S5L; -.
DR PDBsum; 5S5M; -.
DR PDBsum; 5S5N; -.
DR PDBsum; 5S5O; -.
DR PDBsum; 5S5P; -.
DR PDBsum; 5S5Q; -.
DR PDBsum; 5S5R; -.
DR PDBsum; 5S5S; -.
DR PDBsum; 5S5T; -.
DR PDBsum; 5S5U; -.
DR PDBsum; 5S5V; -.
DR PDBsum; 5S5W; -.
DR PDBsum; 5S5X; -.
DR PDBsum; 5S5Y; -.
DR PDBsum; 5S5Z; -.
DR PDBsum; 5S60; -.
DR PDBsum; 5S61; -.
DR PDBsum; 5S62; -.
DR PDBsum; 5S63; -.
DR PDBsum; 5S64; -.
DR PDBsum; 5S65; -.
DR PDBsum; 5S66; -.
DR PDBsum; 5S67; -.
DR PDBsum; 5SB8; -.
DR PDBsum; 5SB9; -.
DR PDBsum; 5SBA; -.
DR PDBsum; 5SBB; -.
DR PDBsum; 5SBC; -.
DR PDBsum; 5SBD; -.
DR PDBsum; 5SBE; -.
DR PDBsum; 5XAF; -.
DR PDBsum; 5XAG; -.
DR PDBsum; 5XHC; -.
DR PDBsum; 5XI5; -.
DR PDBsum; 5XI7; -.
DR PDBsum; 5XIW; -.
DR PDBsum; 5XKE; -.
DR PDBsum; 5XKF; -.
DR PDBsum; 5XKG; -.
DR PDBsum; 5XKH; -.
DR PDBsum; 5XLT; -.
DR PDBsum; 5XLZ; -.
DR PDBsum; 5XP3; -.
DR PDBsum; 5YL2; -.
DR PDBsum; 5YL4; -.
DR PDBsum; 5YLJ; -.
DR PDBsum; 5YLS; -.
DR PDBsum; 5YZ3; -.
DR PDBsum; 5Z4P; -.
DR PDBsum; 5Z4U; -.
DR PDBsum; 5ZXH; -.
DR PDBsum; 6AGK; -.
DR PDBsum; 6BS2; -.
DR PDBsum; 6D88; -.
DR PDBsum; 6EG5; -.
DR PDBsum; 6F7C; -.
DR PDBsum; 6FII; -.
DR PDBsum; 6FJF; -.
DR PDBsum; 6FJM; -.
DR PDBsum; 6FKJ; -.
DR PDBsum; 6FKL; -.
DR PDBsum; 6GF3; -.
DR PDBsum; 6GJ4; -.
DR PDBsum; 6GZE; -.
DR PDBsum; 6H9B; -.
DR PDBsum; 6HX8; -.
DR PDBsum; 6I5C; -.
DR PDBsum; 6JCJ; -.
DR PDBsum; 6K9V; -.
DR PDBsum; 6KNZ; -.
DR PDBsum; 6N47; -.
DR PDBsum; 6QQN; -.
DR PDBsum; 6QTN; -.
DR PDBsum; 6S9E; -.
DR PDBsum; 6SES; -.
DR PDBsum; 6TDE; -.
DR PDBsum; 6TH4; -.
DR PDBsum; 6TIS; -.
DR PDBsum; 6TIU; -.
DR PDBsum; 6TIY; -.
DR PDBsum; 6TIZ; -.
DR PDBsum; 6X1C; -.
DR PDBsum; 6X1E; -.
DR PDBsum; 6X1F; -.
DR PDBsum; 6XER; -.
DR PDBsum; 6XES; -.
DR PDBsum; 6XET; -.
DR PDBsum; 6Y4M; -.
DR PDBsum; 6Y4N; -.
DR PDBsum; 6Y6D; -.
DR PDBsum; 7AU5; -.
DR PDBsum; 7CBZ; -.
DR PDBsum; 7CDA; -.
DR PDBsum; 7CE6; -.
DR PDBsum; 7CE8; -.
DR PDBsum; 7CEK; -.
DR PDBsum; 7CLD; -.
DR PDBsum; 7CPQ; -.
DR PDBsum; 7DP8; -.
DR PDBsum; 7E4P; -.
DR PDBsum; 7E4Q; -.
DR PDBsum; 7E4R; -.
DR PDBsum; 7E4Y; -.
DR PDBsum; 7E4Z; -.
DR PDBsum; 7JFR; -.
DR PDBsum; 7L05; -.
DR PDBsum; 7LZ7; -.
DR PDBsum; 7LZ8; -.
DR PDBsum; 7OGN; -.
DR AlphaFoldDB; P63043; -.
DR SMR; P63043; -.
DR DIP; DIP-61411N; -.
DR IntAct; P63043; 1.
DR iPTMnet; P63043; -.
DR PhosphoSitePlus; P63043; -.
DR Ensembl; ENSRNOT00000087709; ENSRNOP00000069450; ENSRNOG00000053334. [P63043-2]
DR Ensembl; ENSRNOT00000091567; ENSRNOP00000073294; ENSRNOG00000053334. [P63043-3]
DR GeneID; 79423; -.
DR KEGG; rno:79423; -.
DR UCSC; RGD:69349; rat.
DR CTD; 81551; -.
DR RGD; 69349; Stmn4.
DR VEuPathDB; HostDB:ENSRNOG00000053334; -.
DR GeneTree; ENSGT01030000234597; -.
DR InParanoid; P63043; -.
DR OMA; TSMPHRR; -.
DR TreeFam; TF326935; -.
DR EvolutionaryTrace; P63043; -.
DR PRO; PR:P63043; -.
DR Proteomes; UP000002494; Chromosome 15.
DR Bgee; ENSRNOG00000053334; Expressed in cerebellum and 14 other tissues.
DR ExpressionAtlas; P63043; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.
DR GO; GO:0043005; C:neuron projection; IBA:GO_Central.
DR GO; GO:0015631; F:tubulin binding; IBA:GO_Central.
DR GO; GO:0007019; P:microtubule depolymerization; IBA:GO_Central.
DR GO; GO:0031175; P:neuron projection development; IBA:GO_Central.
DR GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IBA:GO_Central.
DR InterPro; IPR028834; Stathmin-4.
DR InterPro; IPR030514; Stathmin_CS.
DR InterPro; IPR000956; Stathmin_fam.
DR InterPro; IPR036002; Stathmin_sf.
DR PANTHER; PTHR10104; PTHR10104; 1.
DR PANTHER; PTHR10104:SF6; PTHR10104:SF6; 1.
DR Pfam; PF00836; Stathmin; 1.
DR PIRSF; PIRSF002285; Stathmin; 1.
DR PRINTS; PR00345; STATHMIN.
DR SUPFAM; SSF101494; SSF101494; 1.
DR PROSITE; PS00563; STATHMIN_1; 1.
DR PROSITE; PS01041; STATHMIN_2; 1.
DR PROSITE; PS51663; STATHMIN_3; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Alternative splicing; Cell projection; Coiled coil;
KW Golgi apparatus; Lipoprotein; Palmitate; Phosphoprotein;
KW Reference proteome.
FT CHAIN 1..189
FT /note="Stathmin-4"
FT /id="PRO_0000182408"
FT DOMAIN 48..189
FT /note="SLD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00998"
FT REGION 168..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 90..189
FT /evidence="ECO:0000255"
FT MOD_RES 90
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:22673903"
FT LIPID 20
FT /note="S-palmitoyl cysteine"
FT /evidence="ECO:0000250"
FT LIPID 22
FT /note="S-palmitoyl cysteine"
FT /evidence="ECO:0000250"
FT VAR_SEQ 36
FT /note="E -> EGWCGRQCRRKGQSQRKGSADWRERREQ (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:9342231"
FT /id="VSP_006280"
FT VAR_SEQ 171..189
FT /note="DKHAEEVRKNKELKEEASR -> EPPAAR (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:9342231"
FT /id="VSP_006281"
FT STRAND 51..58
FT /evidence="ECO:0007829|PDB:4I4T"
FT STRAND 61..69
FT /evidence="ECO:0007829|PDB:4I4T"
FT STRAND 72..76
FT /evidence="ECO:0007829|PDB:6TIY"
FT HELIX 91..184
FT /evidence="ECO:0007829|PDB:4I4T"
FT STRAND 185..187
FT /evidence="ECO:0007829|PDB:6TIZ"
FT MOD_RES P63043-3:54
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:22673903"
SQ SEQUENCE 189 AA; 22087 MW; 4D61AAE5E8131551 CRC64;
MTLAAYKEKM KELPLVSLFC SCFLSDPLNK SSYKYEADTV DLNWCVISDM EVIELNKCTS
GQSFEVILKP PSFDGVPEFN ASLPRRRDPS LEEIQKKLEA AEERRKYQEA ELLKHLAEKR
EHEREVIQKA IEENNNFIKM AKEKLAQKME SNKENREAHL AAMLERLQEK DKHAEEVRKN
KELKEEASR
