ID   SSUE_PSEPU              Reviewed;         197 AA.
AC   O85762;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 2.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=FMN reductase (NADPH);
DE            EC=1.5.1.38;
DE   AltName: Full=FMN reductase;
GN   Name=ssuE;
OS   Pseudomonas putida (Arthrobacter siderocapsulatus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=303;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=DSM 6884 / S-313;
RX   PubMed=10781557; DOI=10.1128/jb.182.10.2869-2878.2000;
RA   Kahnert A., Vermeij P., Wietek C., James P., Leisinger T., Kertesz M.A.;
RT   "The ssu locus plays a key role in organosulfur metabolism in Pseudomonas
RT   putida S-313.";
RL   J. Bacteriol. 182:2869-2878(2000).
RN   [2]
RP   SEQUENCE REVISION.
RA   Kertesz M.A.;
RL   Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably forms a two-component reduced flavin mononucleotide-
CC       dependent monooxygenase by binding to SsuD. Required for growth on
CC       aliphatic sulfonates or methionine but not arylsulfonates.
CC       {ECO:0000269|PubMed:10781557}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=FMNH2 + NADP(+) = FMN + 2 H(+) + NADPH; Xref=Rhea:RHEA:21624,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57618, ChEBI:CHEBI:57783,
CC         ChEBI:CHEBI:58210, ChEBI:CHEBI:58349; EC=1.5.1.38;
CC   -!- SIMILARITY: Belongs to the SsuE family. {ECO:0000305}.
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DR   EMBL; AF075709; AAC31903.2; -; Genomic_DNA.
DR   AlphaFoldDB; O85762; -.
DR   SMR; O85762; -.
DR   STRING; 1240350.AMZE01000010_gene3809; -.
DR   eggNOG; COG0431; Bacteria.
DR   GO; GO:0052873; F:FMN reductase (NADPH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008752; F:FMN reductase activity; IEA:InterPro.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IEA:UniProt.
DR   GO; GO:0046306; P:alkanesulfonate catabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.360; -; 1.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   InterPro; IPR005025; FMN_Rdtase-like.
DR   InterPro; IPR020048; NADPH-dep_FMN_reduc_SsuE.
DR   Pfam; PF03358; FMN_red; 1.
DR   SUPFAM; SSF52218; SSF52218; 1.
DR   TIGRFAMs; TIGR03567; FMN_reduc_SsuE; 1.
PE   3: Inferred from homology;
KW   Flavoprotein; FMN; NADP; Oxidoreductase.
FT   CHAIN           1..197
FT                   /note="FMN reductase (NADPH)"
FT                   /id="PRO_0000160593"
SQ   SEQUENCE   197 AA;  21459 MW;  2244E3289528FDC2 CRC64;
     MLVVSIGGSP STRSRSGVLL ERSRQWLQDR GVEVVSFQVR DFPAEDLLHA RFDSPQVQHF
     QQLVAQADGL VVATPVYKAS FAGALKTLLD LLPERALEHK IVLPIATGGS IAHMLAVDYA
     LKPVLSALKA QETLQGIFAD DSQIAYGEGA KPAQLAPALE ERLHDSLETF HVALARRPRP
     VAPGVLNERL ISARWSI