ID   SPAK_SALTI              Reviewed;         135 AA.
AC   P0A1N1; P39443;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Surface presentation of antigens protein SpaK;
DE   AltName: Full=Invasion protein InvB;
GN   Name=spaK; Synonyms=invB; OrderedLocusNames=STY3018, t2797;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Involved in a secretory pathway responsible for the surface
CC       presentation of determinants needed for the entry of Salmonella species
CC       into mammalian cells. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SpaK family. {ECO:0000305}.
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DR   EMBL; AL513382; CAD06002.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO70358.1; -; Genomic_DNA.
DR   RefSeq; NP_457289.1; NC_003198.1.
DR   RefSeq; WP_001164066.1; NZ_WSUR01000005.1.
DR   AlphaFoldDB; P0A1N1; -.
DR   SMR; P0A1N1; -.
DR   STRING; 220341.16503973; -.
DR   EnsemblBacteria; AAO70358; AAO70358; t2797.
DR   KEGG; stt:t2797; -.
DR   KEGG; sty:STY3018; -.
DR   PATRIC; fig|220341.7.peg.3072; -.
DR   eggNOG; ENOG5032TGU; Bacteria.
DR   HOGENOM; CLU_125441_1_0_6; -.
DR   OMA; TIMEGCQ; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   InterPro; IPR003065; Invas_SpaK.
DR   Pfam; PF03519; Invas_SpaK; 1.
DR   PRINTS; PR01305; SSPAKPROTEIN.
PE   3: Inferred from homology;
KW   Virulence.
FT   CHAIN           1..135
FT                   /note="Surface presentation of antigens protein SpaK"
FT                   /id="PRO_0000180964"
SQ   SEQUENCE   135 AA;  14919 MW;  5F2A1EE477F9D684 CRC64;
     MQHLDIAELV RSALEVSGCD PSLIGGIDSH STIVLDLFAL PSICISVKDD DVWIWAQLGA
     DSMVVLQQRA YEILMTIMEG CHFARGGQLL LGEQNGELTL KALVHPDFLS DGEKFSTALN
     GFYNYLEVFS RSLMR