ID   SPA6L_MOUSE             Reviewed;         347 AA.
AC   B2RV46;
DT   16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Spermatogenesis associated 6-like protein;
GN   Name=Spata6l;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-221, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Lung;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SIMILARITY: Belongs to the SPATA6 family. {ECO:0000305}.
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DR   EMBL; AC113961; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC163993; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC147044; AAI47045.1; -; mRNA.
DR   EMBL; BC147045; AAI47046.1; -; mRNA.
DR   CCDS; CCDS37948.1; -.
DR   RefSeq; NP_941053.2; NM_198651.2.
DR   RefSeq; XP_006527225.1; XM_006527162.3.
DR   AlphaFoldDB; B2RV46; -.
DR   STRING; 10090.ENSMUSP00000025872; -.
DR   iPTMnet; B2RV46; -.
DR   PhosphoSitePlus; B2RV46; -.
DR   MaxQB; B2RV46; -.
DR   PaxDb; B2RV46; -.
DR   PRIDE; B2RV46; -.
DR   Antibodypedia; 24022; 69 antibodies from 13 providers.
DR   DNASU; 381218; -.
DR   Ensembl; ENSMUST00000025872; ENSMUSP00000025872; ENSMUSG00000064202.
DR   GeneID; 381218; -.
DR   KEGG; mmu:381218; -.
DR   UCSC; uc008hcq.1; mouse.
DR   CTD; 55064; -.
DR   MGI; MGI:1918036; Spata6l.
DR   VEuPathDB; HostDB:ENSMUSG00000064202; -.
DR   eggNOG; ENOG502RYM7; Eukaryota.
DR   GeneTree; ENSGT00530000063821; -.
DR   InParanoid; B2RV46; -.
DR   OMA; MWEELAY; -.
DR   OrthoDB; 1154886at2759; -.
DR   PhylomeDB; B2RV46; -.
DR   TreeFam; TF328520; -.
DR   BioGRID-ORCS; 381218; 1 hit in 72 CRISPR screens.
DR   ChiTaRS; 4430402I18Rik; mouse.
DR   PRO; PR:B2RV46; -.
DR   Proteomes; UP000000589; Chromosome 19.
DR   RNAct; B2RV46; protein.
DR   Bgee; ENSMUSG00000064202; Expressed in spermatid and 83 other tissues.
DR   ExpressionAtlas; B2RV46; baseline and differential.
DR   Genevisible; B2RV46; MM.
DR   GO; GO:0097224; C:sperm connecting piece; IEA:InterPro.
DR   GO; GO:0032027; F:myosin light chain binding; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:InterPro.
DR   InterPro; IPR042769; SPATA6_fam.
DR   InterPro; IPR032732; SPATA6_N.
DR   InterPro; IPR027208; SPATA6L.
DR   PANTHER; PTHR16435; PTHR16435; 1.
DR   PANTHER; PTHR16435:SF5; PTHR16435:SF5; 1.
DR   Pfam; PF14909; SPATA6; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..347
FT                   /note="Spermatogenesis associated 6-like protein"
FT                   /id="PRO_0000417503"
FT   REGION          115..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          234..285
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..140
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        244..285
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         218
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6AYJ3"
FT   MOD_RES         221
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:21183079"
SQ   SEQUENCE   347 AA;  39981 MW;  605B0FA6D5D83910 CRC64;
     MRFVKVFEEA IDPGAVAELL ESFLTRFELV QLVSPAWEEL AYYEKNTRDF LFPEPRLASS
     HLGMQREVLM KTAIWFPGIA PKIEFSTRTA ILECVFPCKN RFICEERCRL ERSVSKSHGQ
     RVQATNRKKK PKEKDSDQLP KGTQSRLPSP QRLHLHRPTQ RNHGKSFKFP GERKPPFVVR
     HVDSGNPFGE NNLEHCSKKS RRKPKLINFD LSKKRASSLD SLEANIKVIR EPDERIVLKS
     QPPPPVDSSE SRKPSLSHQG DASLHTETSV TTSQLSRPPS PLNQPLLQER FQPFSQSTWQ
     KIPEGVRSLL TSHRAHPKDS FISETNSIHE RPSYPLKKHL LRAQRYF