SP5E_BACSU
ID SP5E_BACSU Reviewed; 366 AA.
AC P07373; Q45673;
DT 01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1990, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Stage V sporulation protein E;
GN Name=spoVE; OrderedLocusNames=BSU15210;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=2115675; DOI=10.1093/nar/18.13.4021;
RA Sato T., Theeragool G., Yamamoto T., Okamoto M., Kobayashi Y.;
RT "Revised nucleotide sequence of the sporulation gene spoVE from Bacillus
RT subtilis.";
RL Nucleic Acids Res. 18:4021-4021(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3098901; DOI=10.1099/00221287-132-7-1883;
RA Bugaichuk U.D., Piggot P.J.;
RT "Nucleotide sequence of the Bacillus subtilis developmental gene spoVE.";
RL J. Gen. Microbiol. 132:1883-1890(1986).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-46.
RA Theeragool G., Miyao A., Yamada K., Sato T., Kobayashi Y.;
RL Submitted (JAN-1993) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-40.
RC STRAIN=168;
RX PubMed=8436954; DOI=10.1099/00221287-139-2-361;
RA Daniel R.A., Errington J.;
RT "DNA sequence of the murE-murD region of Bacillus subtilis 168.";
RL J. Gen. Microbiol. 139:361-370(1993).
RN [6]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 343-366.
RC STRAIN=168;
RX PubMed=1391053; DOI=10.1016/0300-9084(92)90146-6;
RA Henriques A.O., de Lencastre H., Piggot P.J.;
RT "A Bacillus subtilis morphogene cluster that includes spoVE is homologous
RT to the mra region of Escherichia coli.";
RL Biochimie 74:735-748(1992).
CC -!- FUNCTION: May play an essential role not only during sporulation, but
CC also during vegetative growth.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the SEDS family. SpoVE subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA22807.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=CAA35784.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; X51419; CAA35783.1; -; Genomic_DNA.
DR EMBL; X51419; CAA35784.1; ALT_INIT; Genomic_DNA.
DR EMBL; M15742; AAA22807.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AL009126; CAB13394.1; -; Genomic_DNA.
DR EMBL; D14109; BAA03174.1; -; Genomic_DNA.
DR EMBL; Z15056; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; X64259; CAA45557.1; -; Genomic_DNA.
DR PIR; S10243; SZBS5E.
DR RefSeq; NP_389404.1; NC_000964.3.
DR RefSeq; WP_003244810.1; NZ_JNCM01000035.1.
DR AlphaFoldDB; P07373; -.
DR SMR; P07373; -.
DR STRING; 224308.BSU15210; -.
DR TCDB; 2.A.103.1.3; the bacterial murein precursor exporter (mpe) family.
DR PaxDb; P07373; -.
DR EnsemblBacteria; CAB13394; CAB13394; BSU_15210.
DR GeneID; 936953; -.
DR KEGG; bsu:BSU15210; -.
DR PATRIC; fig|224308.179.peg.1659; -.
DR eggNOG; COG0772; Bacteria.
DR InParanoid; P07373; -.
DR OMA; HDYQKKR; -.
DR PhylomeDB; P07373; -.
DR BioCyc; BSUB:BSU15210-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0015648; F:lipid-linked peptidoglycan transporter activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IBA:GO_Central.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR GO; GO:0008360; P:regulation of cell shape; IBA:GO_Central.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR InterPro; IPR018365; Cell_cycle_FtsW-rel_CS.
DR InterPro; IPR013437; FtsW.
DR InterPro; IPR001182; FtsW/RodA.
DR InterPro; IPR013438; SpoVE.
DR PANTHER; PTHR30474; PTHR30474; 1.
DR Pfam; PF01098; FTSW_RODA_SPOVE; 1.
DR TIGRFAMs; TIGR02614; ftsW; 1.
DR TIGRFAMs; TIGR02615; spoVE; 1.
DR PROSITE; PS00428; FTSW_RODA_SPOVE; 1.
PE 3: Inferred from homology;
KW Cell membrane; Cell shape; Membrane; Reference proteome; Sporulation;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..366
FT /note="Stage V sporulation protein E"
FT /id="PRO_0000062722"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 337..357
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 366 AA; 40132 MW; 3C7045B5D611E427 CRC64;
MTTKKTSPDL LLVIITLLLL TIGLIMVYSA SAVWADYKFD DSFFFAKRQL LFAGIGVIAM
FFIMNVDYWT WRTWSKLLMV ICFFLLVLVL IPGVGMVRNG SRSWIGVGAF SIQPSEFMKL
AMIAFLAKFL SEKQKNITSF RRGFVPALGI VFSAFLIIMC QPDLGTGTVM VGTCIVMIFV
AGARIAHFVF LGLIGLSGFV GLVLSAPYRI KRITSYLNPW EDPLGSGFQI IQSLYAVGPG
GLFGMGLGQS RQKFFYLPEP QTDFIFAILS EELGFIGGTL ILLLFSVLLW RGIRIALGAP
DLYGSFVAVG IISMIAIQVM INIGVVTGLI PVTGITLPFL SYGGSSLTLM LMAVGVLLNV
SRYSRY
