ID   SP15_STRGR              Reviewed;         529 AA.
AC   P19471; P19472;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=55.5 kDa and 49.5 kDa sporulation proteins;
DE   AltName: Full=ORF1590 and ORF1422;
OS   Streptomyces griseus.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2123814; DOI=10.1016/0378-1119(90)90413-l;
RA   Babcock M.J., Kendrick K.E.;
RT   "Transcriptional and translational features of a sporulation gene of
RT   Streptomyces griseus.";
RL   Gene 95:57-63(1990).
CC   -!- FUNCTION: Might be a catalyst/regulator pair of proteins involved in
CC       the temporal controlled sporulation process. The decrease in level of
CC       the smaller protein early in sporulation may relieve negative
CC       regulation of the activity of the larger protein.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative initiation; Named isoforms=2;
CC       Name=55.5 kDa; Synonyms=Long;
CC         IsoId=P19471-1; Sequence=Displayed;
CC       Name=49.5 kDa; Synonyms=Short;
CC         IsoId=P19471-2; Sequence=VSP_018796;
CC   -!- DEVELOPMENTAL STAGE: The amounts of these transcripts increased
CC       significantly during submerged sporulation. The smaller protein is made
CC       in lower amounts during sporulation.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA26817.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M32687; AAA26816.1; -; Genomic_DNA.
DR   EMBL; M32687; AAA26817.1; ALT_INIT; Genomic_DNA.
DR   PIR; JQ0783; JQ0783.
DR   RefSeq; WP_012380227.1; NZ_UAVD01000056.1.
DR   AlphaFoldDB; P19471; -.
DR   SMR; P19471; -.
DR   STRING; 1911.GCA_001715295_02669; -.
DR   GeneID; 6214360; -.
DR   OMA; GWMAFDT; -.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   2: Evidence at transcript level;
KW   Alternative initiation; Sporulation.
FT   CHAIN           1..529
FT                   /note="55.5 kDa and 49.5 kDa sporulation proteins"
FT                   /id="PRO_0000022386"
FT   DNA_BIND        13..31
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   REGION          167..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..55
FT                   /note="Missing (in isoform 49.5 kDa)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_018796"
SQ   SEQUENCE   529 AA;  55458 MW;  0508FE9242BE3BDC CRC64;
     MSREQRGPNE KLGTVLALAG ISNAGLARRV NDLGAQRGLT LRYDKTSVAR WVAKGMVPQG
     AAPHLIAAAI GAKLGRPVPL HEIGLADADP APEVGLAFPR DVGEAVRSAT ELYRLDLAGR
     RGGGGIWQSL AGSFSVSAYA TPASRWLITP ADPSVARDPT AAQAAILGAR GGGSGSPGGA
     GARGPGAAPD ARGAHLLHPG GATPGAAGSV PLQPGPEAVA DASPLRVGHS DVSKLREAAQ
     DARRWDSKYG GGDWRSSMVP ECLRVDAAPL LLGSYTDEVG RALFGASAEL TRLAGWMAFD
     TGQQEAAQRY YIQALRLARA AADVPLGGYV LASMSLQATY RGFADEGVDL AQAAVERNRG
     LATARTMSFF RLVEARAHAK AGDAPAAGAA LKGAESWLER SRAGDSDPPW LGFYGYDRFA
     ADAAECYRDL KAPRQVRRFT EQALSRPTEE FVRSHGLRLV VSAVAELESG NLDAACAAGT
     RAVEVAGRIS SARTTEYVRD LLHRLEPYGD EPRVAELRER ARPLLVTPG