ID   SNPC2_RAT               Reviewed;         359 AA.
AC   Q68FX5;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=snRNA-activating protein complex subunit 2;
DE            Short=SNAPc subunit 2;
DE   AltName: Full=Small nuclear RNA-activating complex polypeptide 2;
DE   AltName: Full=snRNA-activating protein complex 45 kDa subunit;
DE            Short=SNAPc 45 kDa subunit;
GN   Name=Snapc2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lung;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Part of the SNAPc complex required for the transcription of
CC       both RNA polymerase II and III small-nuclear RNA genes. Binds to the
CC       proximal sequence element (PSE), a non-TATA-box basal promoter element
CC       common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA
CC       TATA box (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Part of the SNAPc complex composed of 5 subunits: SNAPC1,
CC       SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC2 interacts with TBP and SNAPC4
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC079077; AAH79077.1; -; mRNA.
DR   RefSeq; NP_001013139.1; NM_001013121.1.
DR   AlphaFoldDB; Q68FX5; -.
DR   SMR; Q68FX5; -.
DR   STRING; 10116.ENSRNOP00000001398; -.
DR   iPTMnet; Q68FX5; -.
DR   PhosphoSitePlus; Q68FX5; -.
DR   PaxDb; Q68FX5; -.
DR   Ensembl; ENSRNOT00000001398; ENSRNOP00000001398; ENSRNOG00000001056.
DR   GeneID; 304204; -.
DR   KEGG; rno:304204; -.
DR   UCSC; RGD:1304589; rat.
DR   CTD; 6618; -.
DR   RGD; 1304589; Snapc2.
DR   eggNOG; ENOG502S260; Eukaryota.
DR   GeneTree; ENSGT00390000017407; -.
DR   HOGENOM; CLU_048442_0_0_1; -.
DR   InParanoid; Q68FX5; -.
DR   OMA; KVPIELW; -.
DR   OrthoDB; 1102879at2759; -.
DR   PhylomeDB; Q68FX5; -.
DR   Reactome; R-RNO-6807505; RNA polymerase II transcribes snRNA genes.
DR   Reactome; R-RNO-76071; RNA Polymerase III Transcription Initiation From Type 3 Promoter.
DR   PRO; PR:Q68FX5; -.
DR   Proteomes; UP000002494; Chromosome 12.
DR   Bgee; ENSRNOG00000001056; Expressed in frontal cortex and 20 other tissues.
DR   Genevisible; Q68FX5; RN.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0016604; C:nuclear body; IBA:GO_Central.
DR   GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR   GO; GO:0009301; P:snRNA transcription; IEA:InterPro.
DR   InterPro; IPR021281; SNAPC2.
DR   PANTHER; PTHR15132; PTHR15132; 1.
DR   Pfam; PF11035; SNAPC2; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..359
FT                   /note="snRNA-activating protein complex subunit 2"
FT                   /id="PRO_0000072022"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          158..222
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          287..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        309..327
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   359 AA;  38569 MW;  63AB3DBFC45AD1C2 CRC64;
     MKPPQRRRKV PARYTGEATG PTAWSPREMR HLLRLLQARR GQPEPDAKEL AKELRGRSEA
     EICRFIQQLK GRVVREAIRK VQPGGRDGPR HRETQLPAPI EVWMDLAEKL TGPLEEALTA
     AFSQVLTIAA AEPLSLLHSK PGKPTKACGR ALVFLSTQDA QKDPAPEGSG PEPMTAADPT
     PEASVPEPKA SGTNPETSGL VPEVSVPDPD APTESLAGSS TERDFAVDFE KIYKYLSSSS
     RGGHGPELSA VESAVVLNLL MSLAEELPHL PCTALVDHLT KTYAQLTAPQ ASLDREKRPR
     PGTEDGGTDS TGPEETGQGS PQASEPTEPR LTWKAAGVCP LNPFLVPLDL LSQALAPAR