ID   SCRK2_SOLHA             Reviewed;         328 AA.
AC   Q7XJ81;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Fructokinase-2;
DE            EC=2.7.1.4;
GN   Name=FRK2;
OS   Solanum habrochaites (Wild tomato) (Lycopersicon hirsutum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=62890;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Levin I., Gilboa N., Cincarevsky F., Oguz I., Petrikov M., Yeselson Y.,
RA   Shen S., Schaffer A.A., Bar M.;
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play an important role in maintaining the flux of carbon
CC       towards starch formation. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+);
CC         Xref=Rhea:RHEA:16125, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:37721, ChEBI:CHEBI:61527, ChEBI:CHEBI:456216; EC=2.7.1.4;
CC   -!- PATHWAY: Glycan biosynthesis; starch biosynthesis.
CC   -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC       {ECO:0000305}.
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DR   EMBL; AY325501; AAP87283.1; -; mRNA.
DR   AlphaFoldDB; Q7XJ81; -.
DR   SMR; Q7XJ81; -.
DR   UniPathway; UPA00152; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008865; F:fructokinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019252; P:starch biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR   InterPro; IPR011611; PfkB_dom.
DR   InterPro; IPR002139; Ribo/fructo_kinase.
DR   InterPro; IPR029056; Ribokinase-like.
DR   Pfam; PF00294; PfkB; 1.
DR   PRINTS; PR00990; RIBOKINASE.
DR   SUPFAM; SSF53613; SSF53613; 1.
DR   PROSITE; PS00583; PFKB_KINASES_1; 1.
DR   PROSITE; PS00584; PFKB_KINASES_2; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Carbohydrate metabolism; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN           1..328
FT                   /note="Fructokinase-2"
FT                   /id="PRO_0000252669"
SQ   SEQUENCE   328 AA;  34719 MW;  30DA6E02F45C2083 CRC64;
     MAVNGASSSG LIVSFGEMLI DFVPTVSGVS LAEAPGFLKA PGGAPANVAI AVTRLGGRSA
     FVGKLGDDEF GHMLAGILKT NGVQADGINF DKGARTALAF VTLRADGERE FMFYRNPSAD
     MLLTPAELNL DLIRSAKVFH YGSISLIVEP CRAAHMKAME VAKEAGALLS YDPNLRLPLW
     PSAEEAKKQI KSIWDSADVI KVSDVELEFL TGSNKIDDES AMSLWHPNLK LLLVTLGEKG
     CNYYTKKFHG TVGGFHVKTV DTTGAGDSFV GALLTKIVDD QTILADEARL KEVLRFSCAC
     GAITTTKKGA IPALPTASEA LTLLKGGA