SCR2_ORYSJ
ID SCR2_ORYSJ Reviewed; 660 AA.
AC Q2QYF3; A3CEG7; B7FA13; Q6L5Z0;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Protein SCARECROW 2;
DE AltName: Full=OsSCR2;
GN Name=SCR2; OrderedLocusNames=Os12g0122000, LOC_Os12g02870;
GN ORFNames=OsJ_033689;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, TISSUE
RP SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Taichung 65;
RX PubMed=12974810; DOI=10.1046/j.1365-313x.2003.01856.x;
RA Kamiya N., Itoh J., Morikami A., Nagato Y., Matsuoka M.;
RT "The SCARECROW gene's role in asymmetric cell divisions in rice plants.";
RL Plant J. 36:45-54(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transcription factor involved in asmmetric cell
CC division in the cortex/endodermis progenitor cell and in the process of
CC stomata and ligule formation in leaves. {ECO:0000269|PubMed:12974810}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12974810}.
CC Note=Localized around the dividing nucleus during asymmetric division.
CC -!- TISSUE SPECIFICITY: Expressed in the root endodermis, in the
CC cortex/endodermal initial and in the quiescent center. Not expressed in
CC the shoot apical meristem itself, but strongly in the L1 layer.
CC {ECO:0000269|PubMed:12974810}.
CC -!- DEVELOPMENTAL STAGE: In the basal portion of the P3 leaf primordium,
CC expressed continuously within the stomatal row. At later stages,
CC expressed in guard mother cell (GMC)-forming cells and in subsidiary
CC mother cell (SMC) just before asymmetric division.
CC {ECO:0000269|PubMed:12974810}.
CC -!- SIMILARITY: Belongs to the GRAS family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAZ19480.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AB180961; BAD22576.1; -; mRNA.
DR EMBL; DP000011; ABA95687.1; -; Genomic_DNA.
DR EMBL; AP008218; BAF29046.1; -; Genomic_DNA.
DR EMBL; AP014968; BAT15657.1; -; Genomic_DNA.
DR EMBL; CM000149; EAZ19480.1; ALT_INIT; Genomic_DNA.
DR EMBL; AK243131; BAH01461.1; -; mRNA.
DR RefSeq; XP_015620600.1; XM_015765114.1.
DR AlphaFoldDB; Q2QYF3; -.
DR SMR; Q2QYF3; -.
DR BioGRID; 820399; 2.
DR IntAct; Q2QYF3; 2.
DR STRING; 4530.OS12T0122000-01; -.
DR PaxDb; Q2QYF3; -.
DR PRIDE; Q2QYF3; -.
DR EnsemblPlants; Os12t0122000-01; Os12t0122000-01; Os12g0122000.
DR GeneID; 4351362; -.
DR Gramene; Os12t0122000-01; Os12t0122000-01; Os12g0122000.
DR KEGG; osa:4351362; -.
DR eggNOG; ENOG502QTMY; Eukaryota.
DR HOGENOM; CLU_011924_7_2_1; -.
DR InParanoid; Q2QYF3; -.
DR OMA; NDESQMR; -.
DR OrthoDB; 772613at2759; -.
DR Proteomes; UP000000763; Chromosome 12.
DR Proteomes; UP000007752; Chromosome 12.
DR Proteomes; UP000059680; Chromosome 12.
DR Genevisible; Q2QYF3; OS.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0008356; P:asymmetric cell division; IBA:GO_Central.
DR GO; GO:0090610; P:bundle sheath cell fate specification; IBA:GO_Central.
DR GO; GO:0009630; P:gravitropism; IBA:GO_Central.
DR GO; GO:0048366; P:leaf development; IBA:GO_Central.
DR GO; GO:0051457; P:maintenance of protein location in nucleus; IBA:GO_Central.
DR GO; GO:0009956; P:radial pattern formation; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR005202; TF_GRAS.
DR PANTHER; PTHR31636; PTHR31636; 1.
DR Pfam; PF03514; GRAS; 1.
DR PROSITE; PS50985; GRAS; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Cytoplasm; Developmental protein; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..660
FT /note="Protein SCARECROW 2"
FT /id="PRO_0000329419"
FT DOMAIN 283..653
FT /note="GRAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..354
FT /note="Leucine repeat I (LRI)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 373..438
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 448..480
FT /note="Leucine repeat II (LRII)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 489..576
FT /note="PFYRE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 579..653
FT /note="SAW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT COILED 262..289
FT /evidence="ECO:0000255"
FT MOTIF 297..301
FT /note="LxCxE motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 404..408
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT COMPBIAS 190..228
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 357
FT /note="S -> N (in Ref. 1; BAD22576)"
FT /evidence="ECO:0000305"
FT CONFLICT 362
FT /note="G -> A (in Ref. 1; BAD22576)"
FT /evidence="ECO:0000305"
FT CONFLICT 365
FT /note="V -> L (in Ref. 1; BAD22576)"
FT /evidence="ECO:0000305"
FT CONFLICT 617
FT /note="A -> V (in Ref. 1; BAD22576)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 660 AA; 70395 MW; AA7025623F66321F CRC64;
MGSSSLLLFP SSSSSATHSS YSPSSSSHAI TSLLPPLPSD HHLLLYLDHQ EQHHLAAAMV
RKRPASDMDL PPPRRHVTGD LSDVTAAAAG APTLSASAQL PALPTQLPAF HHTDMDLAAP
APPAPQQVAA GEGGPPSTAW VDGIIRDIIA SSGAAVSVAQ LIHNVREIIR PCNPDLASIL
ELRLRSLLNS DPAPPPPPPS HPALLPPDAT APPPPPTSVA ALPPPPPAQP DKRRREPQCQ
EQEPNQPQSP KPPTAEETAA AAAAAAAAAA AAAKERKEEQ RRKQRDEEGL HLLTLLLQCA
ESVNADNLDE AHRALLEIAE LATPFGTSTQ RVAAYFAEAM SARLVSSCLG LYAPLPSPSP
AGARVHGRVA AAFQVFNGIS PFVKFSHFTA NQAIQEAFER EERVHIIDLD IMQGLQWPGL
FHILASRPGG PPRVRLTGLG ASMEALEATG KRLSDFADTL GLPFEFCPVA DKAGNLDPEK
LGVTRREAVA VHWLRHSLYD VTGSDSNTLW LIQRLAPKVV TMVEQDLSHS GSFLARFVEA
IHYYSALFDS LDASYSEDSP ERHVVEQQLL SREIRNVLAV GGPARTGDVK FGSWREKLAQ
SGFRVSSLAG SAAAQAALLL GMFPSDGYTL IEENGALKLG WKDLCLLTAS AWRPIQASGR
