ID   SCP_EBVB9               Reviewed;         176 AA.
AC   P14348; Q777G5;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   23-FEB-2022, entry version 73.
DE   RecName: Full=Small capsomere-interacting protein {ECO:0000255|HAMAP-Rule:MF_04022};
GN   Name=SCP {ECO:0000255|HAMAP-Rule:MF_04022}; ORFNames=BFRF3;
OS   Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus.
OX   NCBI_TaxID=10377;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=6087149; DOI=10.1038/310207a0;
RA   Baer R., Bankier A.T., Biggin M.D., Deininger P.L., Farrell P.J.,
RA   Gibson T.J., Hatfull G., Hudson G.S., Satchwell S.C., Seguin C.,
RA   Tuffnell P.S., Barrell B.G.;
RT   "DNA sequence and expression of the B95-8 Epstein-Barr virus genome.";
RL   Nature 310:207-211(1984).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2998075; DOI=10.1016/0042-6822(85)90230-2;
RA   Hudson G.S., Gibson T.J., Barrell B.G.;
RT   "The BamHI F region of the B95-8 Epstein-Barr virus genome.";
RL   Virology 147:99-109(1985).
CC   -!- FUNCTION: Participates in the assembly of the infectious particles by
CC       decorating the outer surface of the capsid shell and thus forming a
CC       layer between the capsid and the tegument. Complexes composed of the
CC       major capsid protein and small capsomere-interacting protein/SCP
CC       assemble together in the host cytoplasm and are translocated to the
CC       nucleus, where they accumulate and participate in capsid assembly.
CC       {ECO:0000255|HAMAP-Rule:MF_04022}.
CC   -!- SUBUNIT: Interacts with the major capsid protein/MCP.
CC       {ECO:0000255|HAMAP-Rule:MF_04022}.
CC   -!- INTERACTION:
CC       P14348; P0C703: MCP; Xeno; NbExp=2; IntAct=EBI-2620158, EBI-9645180;
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04022}. Host
CC       nucleus {ECO:0000255|HAMAP-Rule:MF_04022}.
CC   -!- SIMILARITY: Belongs to the herpesviridae small capsomere-interacting
CC       protein family. {ECO:0000255|HAMAP-Rule:MF_04022}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA24838.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; V01555; CAA24838.1; ALT_INIT; Genomic_DNA.
DR   EMBL; M11923; AAA45870.1; -; Genomic_DNA.
DR   EMBL; AJ507799; CAD53401.1; -; Genomic_DNA.
DR   RefSeq; YP_401651.1; NC_007605.1.
DR   PDB; 6W19; EM; 5.50 A; Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d/e/u=1-176.
DR   PDB; 6W2D; EM; 4.00 A; Z/a/d/e/u=1-176.
DR   PDB; 6W2E; EM; 4.40 A; Z/a/d/e=1-176.
DR   PDB; 7BQX; EM; 4.20 A; 2/Y/Z/y=1-176.
DR   PDB; 7BR7; EM; 4.30 A; 2/Y/Z/m/y=1-176.
DR   PDB; 7BR8; EM; 3.80 A; 2/Y/Z/m/y=1-176.
DR   PDB; 7BSI; EM; 4.10 A; 0/1/G/H/I/J/K/L/P/Q/R/X/Y/Z/m/y=1-176.
DR   PDBsum; 6W19; -.
DR   PDBsum; 6W2D; -.
DR   PDBsum; 6W2E; -.
DR   PDBsum; 7BQX; -.
DR   PDBsum; 7BR7; -.
DR   PDBsum; 7BR8; -.
DR   PDBsum; 7BSI; -.
DR   SMR; P14348; -.
DR   IntAct; P14348; 8.
DR   MINT; P14348; -.
DR   DNASU; 3783701; -.
DR   GeneID; 3783701; -.
DR   KEGG; vg:3783701; -.
DR   Proteomes; UP000153037; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04022; HSV_SCP_gammahv; 1.
DR   InterPro; IPR009299; Herpes_capsid.
DR   Pfam; PF06112; Herpes_capsid; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Capsid protein; Host nucleus; Reference proteome; Virion.
FT   CHAIN           1..176
FT                   /note="Small capsomere-interacting protein"
FT                   /id="PRO_0000115739"
FT   REGION          75..109
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          148..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..109
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   176 AA;  18147 MW;  DAB605ED00F1A656 CRC64;
     MARRLPKPTL QGRLEADFPD SPLLPKFQEL NQNNLPNDVF REAQRSYLVF LTSQFCYEEY
     VQRTFGVPRR QRAIDKRQRA SVAGAGAHAH LGGSSATPVQ QAQAAASAGT GALASSAPST
     AVAQSATPSV SSSISSLRAA TSGATAAASA AAAVDTGSGG GGQPHDTAPR GARKKQ