ID   SCPL3_CAEEL             Reviewed;         287 AA.
AC   Q9N4V4; Q86S75;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=CTD small phosphatase-like protein 3;
DE            Short=CTDSP-like 3;
DE            EC=3.1.3.-;
GN   Name=scpl-3; ORFNames=Y47D9A.2;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Probable phosphatase. {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=a;
CC         IsoId=Q9N4V4-1; Sequence=Displayed;
CC       Name=b;
CC         IsoId=Q9N4V4-2; Sequence=VSP_033225;
CC   -!- SIMILARITY: Belongs to the CTDSPL2 family. {ECO:0000305}.
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DR   EMBL; FO080843; CCD67161.1; -; Genomic_DNA.
DR   EMBL; FO080843; CCD67162.1; -; Genomic_DNA.
DR   RefSeq; NP_491348.1; NM_058947.5.
DR   AlphaFoldDB; Q9N4V4; -.
DR   SMR; Q9N4V4; -.
DR   BioGRID; 37502; 1.
DR   IntAct; Q9N4V4; 1.
DR   STRING; 6239.Y47D9A.2b; -.
DR   EPD; Q9N4V4; -.
DR   EnsemblMetazoa; Y47D9A.2a.1; Y47D9A.2a.1; WBGene00021629. [Q9N4V4-1]
DR   GeneID; 172032; -.
DR   UCSC; Y47D9A.2b; c. elegans. [Q9N4V4-1]
DR   CTD; 172032; -.
DR   WormBase; Y47D9A.2a; CE22072; WBGene00021629; scpl-3. [Q9N4V4-1]
DR   eggNOG; KOG1605; Eukaryota.
DR   GeneTree; ENSGT01040000240503; -.
DR   HOGENOM; CLU_020262_4_1_1; -.
DR   InParanoid; Q9N4V4; -.
DR   OrthoDB; 1176152at2759; -.
DR   PhylomeDB; Q9N4V4; -.
DR   PRO; PR:Q9N4V4; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   Bgee; WBGene00021629; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   ExpressionAtlas; Q9N4V4; baseline and differential.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.40.50.1000; -; 1.
DR   InterPro; IPR011948; Dullard_phosphatase.
DR   InterPro; IPR004274; FCP1_dom.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR023214; HAD_sf.
DR   Pfam; PF03031; NIF; 1.
DR   SMART; SM00577; CPDc; 1.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   TIGRFAMs; TIGR02251; HIF-SF_euk; 1.
DR   PROSITE; PS50969; FCP1; 1.
PE   3: Inferred from homology;
KW   Alternative splicing; Hydrolase; Protein phosphatase; Reference proteome.
FT   CHAIN           1..287
FT                   /note="CTD small phosphatase-like protein 3"
FT                   /id="PRO_0000331474"
FT   DOMAIN          60..219
FT                   /note="FCP1 homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00336"
FT   VAR_SEQ         222
FT                   /note="L -> LVNFHFEIKVKTNSICLAILSSNNFQ (in isoform b)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_033225"
SQ   SEQUENCE   287 AA;  33163 MW;  ADE2F57CB4FF1F41 CRC64;
     MSNVTPKLVW PEDDYVDESL LEDHQGPARL EYDALVMLAN LPPLTEEIMS RCPALPVKTR
     STPEYTLVLD LDETLVHCSL TPLDNATMVF PVVFQNITYQ VYVRLRPHLR TFLSRMAKTF
     EIIIFTASKK VYANKLCDIL DPRKNHIRHR LFREHCVCVF GNYVKDLTIL GRDPSKTMIL
     DNAVQSFAYQ LDNGIPIESW FHDRNDTELL KLCSFLEAIP TLGRDVREIL RHKYRLRDHI
     PFYSIIHQQE GPGRLPLLEV APPPVTEPND EQLITQVVQK HPQLVQG