ID   SCOC_BRUMA              Reviewed;         122 AA.
AC   A8NJZ7;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Short coiled-coil protein homolog;
GN   ORFNames=Bm1_04115;
OS   Brugia malayi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=6279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17885136; DOI=10.1126/science.1145406;
RA   Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA   Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA   Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA   Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA   Pop M., White O., Barton G.J., Carlow C.K.S., Crawford M.J., Daub J.,
RA   Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA   Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.-W.,
RA   Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA   McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA   Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA   Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA   Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA   Blaxter M.L., Scott A.L.;
RT   "Draft genome of the filarial nematode parasite Brugia malayi.";
RL   Science 317:1756-1760(2007).
CC   -!- FUNCTION: Positive regulator of amino acid starvation-induced
CC       autophagy. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Cytoplasmic side
CC       {ECO:0000250}. Golgi apparatus, trans-Golgi network {ECO:0000250}.
CC       Cytoplasm, cytosol {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SCOC family. {ECO:0000305}.
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DR   EMBL; DS237409; EDP38868.1; -; Genomic_DNA.
DR   RefSeq; XP_001892311.1; XM_001892276.1.
DR   AlphaFoldDB; A8NJZ7; -.
DR   SMR; A8NJZ7; -.
DR   STRING; 6279.A8NJZ7; -.
DR   GeneID; 6095763; -.
DR   KEGG; bmy:BM_BM5628; -.
DR   CTD; 6095763; -.
DR   WormBase; Bm5628a; BM33824; WBGene00225889; Bma-unc-69.
DR   InParanoid; A8NJZ7; -.
DR   OrthoDB; 1581498at2759; -.
DR   Proteomes; UP000006672; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019357; SCOC.
DR   PANTHER; PTHR21614; PTHR21614; 1.
DR   Pfam; PF10224; DUF2205; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Golgi apparatus; Membrane; Reference proteome.
FT   CHAIN           1..122
FT                   /note="Short coiled-coil protein homolog"
FT                   /id="PRO_0000334169"
FT   REGION          17..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          53..95
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        17..37
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   122 AA;  13625 MW;  7A468CF14A8F8E5A CRC64;
     MVEINCFRLM STDTTVTNET DNFPLVDDES QGSSIDTGGR IPRPAQPLPR DESDDQEEKA
     RLISQVLELQ NTLDDLSQRV DSVKEESLKL RSENQVLGQY IQNLMASSAV FQPAQSKAPQ
     TK