SCOB_XANCB
ID SCOB_XANCB Reviewed; 213 AA.
AC B0RVK3; O34263;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Succinyl-CoA:3-ketoacid coenzyme A transferase subunit B;
DE EC=2.8.3.5;
DE AltName: Full=OXCT B;
DE AltName: Full=Succinyl-CoA:3-oxoacid CoA-transferase;
GN Name=lpsJ; Synonyms=wxcJ; OrderedLocusNames=xcc-b100_3727;
OS Xanthomonas campestris pv. campestris (strain B100).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=509169;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RX PubMed=9385134; DOI=10.1007/s002030050520;
RA Steinmann D., Koeplin R., Puehler A., Niehaus K.;
RT "Xanthomonas campestris pv. campestris lpsI and lpsJ genes encoding
RT putative proteins with sequence similarity to the alpha- and beta-subunits
RT of 3-oxoacid CoA-transferases are involved in LPS biosynthesis.";
RL Arch. Microbiol. 168:441-447(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B100;
RX PubMed=18304669; DOI=10.1016/j.jbiotec.2007.12.013;
RA Vorhoelter F.-J., Schneiker S., Goesmann A., Krause L., Bekel T.,
RA Kaiser O., Linke B., Patschkowski T., Rueckert C., Schmid J., Sidhu V.K.,
RA Sieber V., Tauch A., Watt S.A., Weisshaar B., Becker A., Niehaus K.,
RA Puehler A.;
RT "The genome of Xanthomonas campestris pv. campestris B100 and its use for
RT the reconstruction of metabolic pathways involved in xanthan
RT biosynthesis.";
RL J. Biotechnol. 134:33-45(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate;
CC Xref=Rhea:RHEA:24564, ChEBI:CHEBI:30031, ChEBI:CHEBI:35973,
CC ChEBI:CHEBI:57292, ChEBI:CHEBI:90726; EC=2.8.3.5;
CC Evidence={ECO:0000255|PROSITE-ProRule:PRU10034};
CC -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC biosynthesis.
CC -!- SUBUNIT: Heterodimer of a subunit A and a subunit B. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the 3-oxoacid CoA-transferase subunit B family.
CC {ECO:0000305}.
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DR EMBL; AF204145; AAK53493.1; -; Genomic_DNA.
DR EMBL; AM920689; CAP53094.1; -; Genomic_DNA.
DR AlphaFoldDB; B0RVK3; -.
DR SMR; B0RVK3; -.
DR KEGG; xca:xcc-b100_3727; -.
DR HOGENOM; CLU_019942_4_1_6; -.
DR OMA; VAMMHTN; -.
DR UniPathway; UPA00030; -.
DR Proteomes; UP000001188; Chromosome.
DR GO; GO:0008260; F:3-oxoacid CoA-transferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR012791; 3-oxoacid_CoA-transf_B.
DR InterPro; IPR004165; CoA_trans_fam_I.
DR InterPro; IPR004164; CoA_transf_AS.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR13707; PTHR13707; 1.
DR Pfam; PF01144; CoA_trans; 1.
DR SMART; SM00882; CoA_trans; 1.
DR SUPFAM; SSF100950; SSF100950; 1.
DR TIGRFAMs; TIGR02428; pcaJ_scoB_fam; 1.
DR PROSITE; PS01274; COA_TRANSF_2; 1.
PE 3: Inferred from homology;
KW Lipopolysaccharide biosynthesis; Transferase.
FT CHAIN 1..213
FT /note="Succinyl-CoA:3-ketoacid coenzyme A transferase
FT subunit B"
FT /id="PRO_0000333182"
FT ACT_SITE 47
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10034"
FT CONFLICT 12..13
FT /note="AA -> P (in Ref. 1; AAK53493)"
FT /evidence="ECO:0000305"
FT CONFLICT 107..114
FT /note="VTDRGDLA -> SPTAATSP (in Ref. 1; AAK53493)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 213 AA; 22328 MW; 6380A78477AAD020 CRC64;
MAWTRDQMAA RAARELTDGA YVNLGIGLPT LVANHIPDGV DVWLQSENGL LGIGPFPGED
EVDADLINAG KQTVTARAGA SYFGSHDSFA MIRGGHIDLA ILGAMQVTDR GDLANWMVPG
KMVKGMGGAM DLVAGVKRVV VLMEHVAKDG THKILPQCDL PLTGVGVVDR IITDLAVFDV
TDGGLVLVEA AEGVGLEELR AKTGVAFVVQ TRG
